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The map label for this gene is cobL [H]

Identifier: 123968999

GI number: 123968999

Start: 1251327

End: 1252601

Strand: Direct

Name: cobL [H]

Synonym: A9601_14671

Alternate gene names: 123968999

Gene position: 1251327-1252601 (Clockwise)

Preceding gene: 123968991

Following gene: 123969002

Centisome position: 74.93

GC content: 29.1

Gene sequence:

>1275_bases
ATGACTGAAAAAAAAAGAAAAATTCATGTAGTAGGAATTAATTCTTATAAATTTGAGGATCTATCTTTCAAATTACAAAA
TCTATTTTTAGAAACAGAAAATATTGCAGTTCCAAATTCATATTTTGAAAAAATAAAATCATGGAGCGAAAATGGTTTAG
AAAAAAATAAATTATTTTTTTCGAGCAACAGTAATCAGGAACTTGTTAACTGGCTTAGATCACAAAAAACTGATGTTATT
TTAATTTCAAGAGGAGATCCTCTCTGGTTTGGAATTGGGAGAATACTACTAGAAAATTTTTCAAAAGATGAATTAAGTTT
CTACCCTGCAAATACTTGCATTCAATTAGCATTTAGTAAGTTAAAGTTCCCATGGCAAGATACTGTTAATGTGAGTATTC
ACGGAAGAGATTCGACTAAGTTAATTGAAGCTCTTAAAGCAAGACCGTCAAATTTGGCTGTCATTACAGATTCAAATAAC
AAAAGTCTAGAAATAATCAAAAAAAATTTATCAGAACTTGATCTGATTGACATCTATGATTTTTGGCTCTGTGAAGAAAT
AGGCTTCGAAAATGAAAAAATCAGGAAATTAAATCTTAAAGAGTCATTGCCCTCAGATATATCAAATTTGAATATTGCTA
TTCTTTCAAAAAAAAAGGAAAATTATTCGAACAACAATCTTCCTCTATTCGGAATCAATGACAATGTTTTTAAGACTTTT
GATGATAGACCAAATTTATTAACTAAGAGAGAAGTTCGCATTCAAATATTAGCTGCTTTAGAGCTCCCAAGAAATGGTGT
CATTTGGGATATAGGAGCAGGTTGTGGATCAATTGGTTTAGAGGCATTAAAGCTAAGGCCTAATTTGGATTTGTTTTGTT
TCGATAAAAGGATTGGCTCAAAAGAATTAATACTAGAAAACTCAAAAAGGCTTGACGTCAACCCAAAATTTATTTTTGAG
GAAGACATAAATCACACCTTGAATGCGAGAAATTTAAGTTCTTTTGAAAACCCTAATAGATTAATAATTGGAGGATGTGA
TAAAAAAACTAAACTCCAGATTATTAATAAAATTGCACAAGATATGGATATTGGAGACATTATCGTTATCCCAATAATAA
ATATTCAAACTATTAAAGAATTGAAAGAGGAATTAGAAGATAAAAATTTCAAAACAAATTTAAATTTAATTCAGACCTAT
AAAAGCTTAAGTATTGCGGAGGGAATGAGACTAGAACCAAATAATCCTGTTTTTCTATTAACAGGGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTCTTCTTTCAGACAATTGATTTATTATGGAAGTTCGAATAATCATAAGATAATTTAATAAAACATTCAAATAAATAAG
TTTCTTTTAATTAAATATTC

Downstream 100 bases:

>100_bases
ATTCAAATAATTGTTATTTTTCAGGTTTAGCCACATGGGGTAAACCCCAACCAAGTTTATTTCTTAAAACTTGGAAAAAT
TCGTGATCTTCAAGTCTAAT

Product: putative precorrin-6y methylase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTEKKRKIHVVGINSYKFEDLSFKLQNLFLETENIAVPNSYFEKIKSWSENGLEKNKLFFSSNSNQELVNWLRSQKTDVI
LISRGDPLWFGIGRILLENFSKDELSFYPANTCIQLAFSKLKFPWQDTVNVSIHGRDSTKLIEALKARPSNLAVITDSNN
KSLEIIKKNLSELDLIDIYDFWLCEEIGFENEKIRKLNLKESLPSDISNLNIAILSKKKENYSNNNLPLFGINDNVFKTF
DDRPNLLTKREVRIQILAALELPRNGVIWDIGAGCGSIGLEALKLRPNLDLFCFDKRIGSKELILENSKRLDVNPKFIFE
EDINHTLNARNLSSFENPNRLIIGGCDKKTKLQIINKIAQDMDIGDIIVIPIINIQTIKELKEELEDKNFKTNLNLIQTY
KSLSIAEGMRLEPNNPVFLLTGKK

Sequences:

>Translated_424_residues
MTEKKRKIHVVGINSYKFEDLSFKLQNLFLETENIAVPNSYFEKIKSWSENGLEKNKLFFSSNSNQELVNWLRSQKTDVI
LISRGDPLWFGIGRILLENFSKDELSFYPANTCIQLAFSKLKFPWQDTVNVSIHGRDSTKLIEALKARPSNLAVITDSNN
KSLEIIKKNLSELDLIDIYDFWLCEEIGFENEKIRKLNLKESLPSDISNLNIAILSKKKENYSNNNLPLFGINDNVFKTF
DDRPNLLTKREVRIQILAALELPRNGVIWDIGAGCGSIGLEALKLRPNLDLFCFDKRIGSKELILENSKRLDVNPKFIFE
EDINHTLNARNLSSFENPNRLIIGGCDKKTKLQIINKIAQDMDIGDIIVIPIINIQTIKELKEELEDKNFKTNLNLIQTY
KSLSIAEGMRLEPNNPVFLLTGKK
>Mature_423_residues
TEKKRKIHVVGINSYKFEDLSFKLQNLFLETENIAVPNSYFEKIKSWSENGLEKNKLFFSSNSNQELVNWLRSQKTDVIL
ISRGDPLWFGIGRILLENFSKDELSFYPANTCIQLAFSKLKFPWQDTVNVSIHGRDSTKLIEALKARPSNLAVITDSNNK
SLEIIKKNLSELDLIDIYDFWLCEEIGFENEKIRKLNLKESLPSDISNLNIAILSKKKENYSNNNLPLFGINDNVFKTFD
DRPNLLTKREVRIQILAALELPRNGVIWDIGAGCGSIGLEALKLRPNLDLFCFDKRIGSKELILENSKRLDVNPKFIFEE
DINHTLNARNLSSFENPNRLIIGGCDKKTKLQIINKIAQDMDIGDIIVIPIINIQTIKELKEELEDKNFKTNLNLIQTYK
SLSIAEGMRLEPNNPVFLLTGKK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 48639; Mature: 48507

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKRKIHVVGINSYKFEDLSFKLQNLFLETENIAVPNSYFEKIKSWSENGLEKNKLFF
CCCCCCEEEEEECCCEEECHHHEEEEHEEEEECCEECCHHHHHHHHHHHHCCCCCCEEEE
SSNSNQELVNWLRSQKTDVILISRGDPLWFGIGRILLENFSKDELSFYPANTCIQLAFSK
ECCCCHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
LKFPWQDTVNVSIHGRDSTKLIEALKARPSNLAVITDSNNKSLEIIKKNLSELDLIDIYD
HCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEHHH
FWLCEEIGFENEKIRKLNLKESLPSDISNLNIAILSKKKENYSNNNLPLFGINDNVFKTF
HHHHHHHCCCCCCEEEECCHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCEECC
DDRPNLLTKREVRIQILAALELPRNGVIWDIGAGCGSIGLEALKLRPNLDLFCFDKRIGS
CCCCCCCCCHHEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCC
KELILENSKRLDVNPKFIFEEDINHTLNARNLSSFENPNRLIIGGCDKKTKLQIINKIAQ
CEEEEECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
DMDIGDIIVIPIINIQTIKELKEELEDKNFKTNLNLIQTYKSLSIAEGMRLEPNNPVFLL
HCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEE
TGKK
ECCC
>Mature Secondary Structure 
TEKKRKIHVVGINSYKFEDLSFKLQNLFLETENIAVPNSYFEKIKSWSENGLEKNKLFF
CCCCCEEEEEECCCEEECHHHEEEEHEEEEECCEECCHHHHHHHHHHHHCCCCCCEEEE
SSNSNQELVNWLRSQKTDVILISRGDPLWFGIGRILLENFSKDELSFYPANTCIQLAFSK
ECCCCHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
LKFPWQDTVNVSIHGRDSTKLIEALKARPSNLAVITDSNNKSLEIIKKNLSELDLIDIYD
HCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEHHH
FWLCEEIGFENEKIRKLNLKESLPSDISNLNIAILSKKKENYSNNNLPLFGINDNVFKTF
HHHHHHHCCCCCCEEEECCHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCEECC
DDRPNLLTKREVRIQILAALELPRNGVIWDIGAGCGSIGLEALKLRPNLDLFCFDKRIGS
CCCCCCCCCHHEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCC
KELILENSKRLDVNPKFIFEEDINHTLNARNLSSFENPNRLIIGGCDKKTKLQIINKIAQ
CEEEEECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
DMDIGDIIVIPIINIQTIKELKEELEDKNFKTNLNLIQTYKSLSIAEGMRLEPNNPVFLL
HCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEE
TGKK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]