Click here to switch to the map view.

The map label for this gene is rrmA [C]

Identifier: 123968977

GI number: 123968977

Start: 1230158

End: 1230829

Strand: Direct

Name: rrmA [C]

Synonym: A9601_14451

Alternate gene names: 123968977

Gene position: 1230158-1230829 (Clockwise)

Preceding gene: 123968976

Following gene: 123968978

Centisome position: 73.67

GC content: 29.61

Gene sequence:

>672_bases
ATGAGAGAAATAGATTTCATGAGTTCACTTCATAAAAGTACAAAGAGAAATTATTTAGAAAGAGTAAATGACAAAGAATT
CCCAAAGTCTAAAGCAGCAACTCTAGCAAAAAAATTTGACTTTGATTACTGGGATGGAGACAGACGAATTAACTATGGCG
GATATAGTTACAAACCAGGCAGGTGGACAAAAGTTGCCCAAGAAATGATAAATACTTACAATTTAAAATCTGATTCAAAG
ATTCTTGATATTGGTTGTGGTAAGGGATACTTATTATATGAATTTAGAAAATTACTTCCAGAATGTGAAGTTTTTGGTAT
TGATATTTCAGAATATGCTATTAAAAATTCTCATGAAAAAGTAAGAGAAAATTTGAAATTAGGATCCGCCAATAATCTCC
CATTTAATTCAAAGATGTTTGATTTAGTAATTTCTATAAATACTCTACATAATTTATATTGTTTTGATCTTTTCTCGGCT
TTAAAAGAAATTGAGAGAGTTGCCAAAATAAATAAATATATATGTGTTGAAAGCTATAGGAATGAGGAGGAGAAAGCTAA
CCTTCTATACTGGCAAGTTACTTGTGAGGCGTTTAATAATCCAAAAGAATGGGAATGGTGGTTTAATCAAAGTGGATATA
CTGGGGATTATTCATATATATATTTTTCTTAA

Upstream 100 bases:

>100_bases
GTAATTCTCAAGGAAACTTTAATTTAAACGAAGATGAGAGATCAATATTCTTTTTAAAGTGAACATTAAAGTAAGATAAT
TAGATATACAAAAAGATAAT

Downstream 100 bases:

>100_bases
AAAAAGATTAATGTTATTATCTTAAAAAAAATTATGAATTCAAAAAGAAGTGAGCCCTGGTTTAATGAAAGACTAAATTC
AATTACTGGTCAGAAAAATT

Product: SAM-dependent methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: Methyltransferase Type; SAM-Dependent Methyltransferase; Protein-L-Isoaspartate(D-Aspartate) O-Methyltransferase; S-Adenosyl-L-Methionine-Dependent Methyltransferase

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MREIDFMSSLHKSTKRNYLERVNDKEFPKSKAATLAKKFDFDYWDGDRRINYGGYSYKPGRWTKVAQEMINTYNLKSDSK
ILDIGCGKGYLLYEFRKLLPECEVFGIDISEYAIKNSHEKVRENLKLGSANNLPFNSKMFDLVISINTLHNLYCFDLFSA
LKEIERVAKINKYICVESYRNEEEKANLLYWQVTCEAFNNPKEWEWWFNQSGYTGDYSYIYFS

Sequences:

>Translated_223_residues
MREIDFMSSLHKSTKRNYLERVNDKEFPKSKAATLAKKFDFDYWDGDRRINYGGYSYKPGRWTKVAQEMINTYNLKSDSK
ILDIGCGKGYLLYEFRKLLPECEVFGIDISEYAIKNSHEKVRENLKLGSANNLPFNSKMFDLVISINTLHNLYCFDLFSA
LKEIERVAKINKYICVESYRNEEEKANLLYWQVTCEAFNNPKEWEWWFNQSGYTGDYSYIYFS
>Mature_223_residues
MREIDFMSSLHKSTKRNYLERVNDKEFPKSKAATLAKKFDFDYWDGDRRINYGGYSYKPGRWTKVAQEMINTYNLKSDSK
ILDIGCGKGYLLYEFRKLLPECEVFGIDISEYAIKNSHEKVRENLKLGSANNLPFNSKMFDLVISINTLHNLYCFDLFSA
LKEIERVAKINKYICVESYRNEEEKANLLYWQVTCEAFNNPKEWEWWFNQSGYTGDYSYIYFS

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 26468; Mature: 26468

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIDFMSSLHKSTKRNYLERVNDKEFPKSKAATLAKKFDFDYWDGDRRINYGGYSYKPG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCCCC
RWTKVAQEMINTYNLKSDSKILDIGCGKGYLLYEFRKLLPECEVFGIDISEYAIKNSHEK
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCHHH
VRENLKLGSANNLPFNSKMFDLVISINTLHNLYCFDLFSALKEIERVAKINKYICVESYR
HHHHCCCCCCCCCCCCCCCEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHC
NEEEKANLLYWQVTCEAFNNPKEWEWWFNQSGYTGDYSYIYFS
CCCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEEC
>Mature Secondary Structure
MREIDFMSSLHKSTKRNYLERVNDKEFPKSKAATLAKKFDFDYWDGDRRINYGGYSYKPG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCCCC
RWTKVAQEMINTYNLKSDSKILDIGCGKGYLLYEFRKLLPECEVFGIDISEYAIKNSHEK
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCHHH
VRENLKLGSANNLPFNSKMFDLVISINTLHNLYCFDLFSALKEIERVAKINKYICVESYR
HHHHCCCCCCCCCCCCCCCEEHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHC
NEEEKANLLYWQVTCEAFNNPKEWEWWFNQSGYTGDYSYIYFS
CCCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA