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The map label for this gene is cobU [H]

Identifier: 123968532

GI number: 123968532

Start: 869704

End: 870264

Strand: Direct

Name: cobU [H]

Synonym: A9601_09991

Alternate gene names: 123968532

Gene position: 869704-870264 (Clockwise)

Preceding gene: 123968531

Following gene: 123968533

Centisome position: 52.08

GC content: 30.12

Gene sequence:

>561_bases
ATGAATGCCAAGGTTTTAAATATTAGTGAATATTCATCTCATATAGTTTTAATTACAGGAGGGACAAAGAGTGGAAAAAG
TGAATTCGCGGAGCATCTTGCAAAGGGGGTAAAAAAATTATCATATGTTGCCTTATCTGAAAACAATTTGGATGATAAAG
AATGGCAAGATAAAATTAATTTACATCGAAAAAGAAGACCAAAAGATTGGAAATTAATAGAAACGACAGATCTATTAAAT
ACATTAAGGAATGAAGAAGGTCCATTATTAATAGATTCTATTGGGGGATTCGTTATGAAAAGTATTGGAAAGGAACAAAA
AGAATGGTTAACAAAAATGAATTCACTTATAAGTCTCTTAATGAAAAGAAAAAGCATAACAATTATTGTTGGAGAACAAG
TGGGTTGGAGTTTGGTCTCTGAATATAAAATTGGTAATACATATATTGAGAGAATCGGCGAAATTCAAAAGAGAATAACC
AAAATATCAAAAGATAATTGGCTGGCCATAAACGGCAGAGCAATCAAAATAGATGAAATAAGTATTGAAATACCTACTTA
A

Upstream 100 bases:

>100_bases
GAGAGTTCAACTGCTACTTATATAGTTGTAGGTTTGTTAATTGCTGCCACGATTATTCCTCTAGCAACATGGTGGTATTT
CTCTAAATAATAGAGAATTT

Downstream 100 bases:

>100_bases
AATTGGAAGTCGCTCTTTTTGAACCTAGAATCCCACAAAATACTGGTAATATTGCCAGATCATGTGCTGCATTTAATATA
CCTTTAAATCTTATAGAGCC

Product: putative cobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNAKVLNISEYSSHIVLITGGTKSGKSEFAEHLAKGVKKLSYVALSENNLDDKEWQDKINLHRKRRPKDWKLIETTDLLN
TLRNEEGPLLIDSIGGFVMKSIGKEQKEWLTKMNSLISLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGEIQKRIT
KISKDNWLAINGRAIKIDEISIEIPT

Sequences:

>Translated_186_residues
MNAKVLNISEYSSHIVLITGGTKSGKSEFAEHLAKGVKKLSYVALSENNLDDKEWQDKINLHRKRRPKDWKLIETTDLLN
TLRNEEGPLLIDSIGGFVMKSIGKEQKEWLTKMNSLISLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGEIQKRIT
KISKDNWLAINGRAIKIDEISIEIPT
>Mature_186_residues
MNAKVLNISEYSSHIVLITGGTKSGKSEFAEHLAKGVKKLSYVALSENNLDDKEWQDKINLHRKRRPKDWKLIETTDLLN
TLRNEEGPLLIDSIGGFVMKSIGKEQKEWLTKMNSLISLLMKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGEIQKRIT
KISKDNWLAINGRAIKIDEISIEIPT

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=24.3093922651934, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21179; Mature: 21179

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKVLNISEYSSHIVLITGGTKSGKSEFAEHLAKGVKKLSYVALSENNLDDKEWQDKIN
CCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
LHRKRRPKDWKLIETTDLLNTLRNEEGPLLIDSIGGFVMKSIGKEQKEWLTKMNSLISLL
HHHHCCCCCCEEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGEIQKRITKISKDNWLAINGRAIKIDEI
HHCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEE
SIEIPT
EEEECC
>Mature Secondary Structure
MNAKVLNISEYSSHIVLITGGTKSGKSEFAEHLAKGVKKLSYVALSENNLDDKEWQDKIN
CCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
LHRKRRPKDWKLIETTDLLNTLRNEEGPLLIDSIGGFVMKSIGKEQKEWLTKMNSLISLL
HHHHCCCCCCEEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MKRKSITIIVGEQVGWSLVSEYKIGNTYIERIGEIQKRITKISKDNWLAINGRAIKIDEI
HHCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEE
SIEIPT
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]