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The map label for this gene is ubiE [H]

Identifier: 123968023

GI number: 123968023

Start: 421224

End: 421925

Strand: Direct

Name: ubiE [H]

Synonym: A9601_04861

Alternate gene names: 123968023

Gene position: 421224-421925 (Clockwise)

Preceding gene: 123968022

Following gene: 123968025

Centisome position: 25.22

GC content: 27.07

Gene sequence:

>702_bases
ATGAAATTTACAAAAACTATCGAAGTCAAAAATATATTTAATAAAATTTCCTATAAATATGACTTTTTAAATAATCTATT
AAGTTTTGGGCTGCACAGATTATGGAAAAGGAAATTGGTTAATTTATTGGAACCTTTAAATGGTGAAAATTGGGCTGATT
TATGCTGTGGAACTGGCGATTTAGCATTCTTAATTTCTGAGAGGGTTAGTCCAAGTGGTTCAATTACTGGGATTGACAGT
GCAGAAGATATTTTAAATATTGCGAAGAAAAAATCAGAGCTTAAAAAAAATAAATTTATTAAGTGGGAAATTAAAGATGT
ATTAGAAATTAATGATTATTCAAAAAATTTTGATGGGATTTGTATGTCATATGGACTAAGAAACTTGAATAATGTTGAAG
AAGGAATAAAAAAAGTTTTTGATCTTTTGAAGGATAAGGGAAGAGCAGGATTTTTGGATTTTAATCACTCAACAAGAAAT
TCTTTATCCAATATTTTTCAGAAAATTTATTTGAGATTAATCGTAGTAACCATTTCGCGGCTTTTTAATTTAGGTCCAGA
ATACGCATATATTGAAAAAAGTATTAGTAATTTTCCAAAGAAAAATGAACTTATAAATATTGCTAAGGAAGTTGGATTTA
AAAAAGCTGAATATAGGACTATTTTGGGAGGGCAAATGGGAATATTAATTTTAACTAAATAA

Upstream 100 bases:

>100_bases
AAAGAAATAAAAACTTTCCTCCTCGAAAAAAAACTCTCAATTAGACCATATGAATAAAAATTTTAATTAAATCCCAAAAA
AATAAGTTAAAAATTTAAAA

Downstream 100 bases:

>100_bases
AGAATTTAGTTTTTTATTTTTCTCCAACAAAAAGAACACTTTCCCCATCTTTTGATTTCGCCGTCAGGAGTAGGTGAATT
ACAAAGAGGACAAATGCACA

Product: ubiquinone/menaquinone biosynthesis methyltransferases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVNLLEPLNGENWADLCCGTGDLAFLISERVSPSGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEEGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNELINIAKEVGFKKAEYRTILGGQMGILILTK

Sequences:

>Translated_233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVNLLEPLNGENWADLCCGTGDLAFLISERVSPSGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEEGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNELINIAKEVGFKKAEYRTILGGQMGILILTK
>Mature_233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVNLLEPLNGENWADLCCGTGDLAFLISERVSPSGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEEGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNELINIAKEVGFKKAEYRTILGGQMGILILTK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=224, Percent_Identity=27.2321428571429, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17557039, Length=227, Percent_Identity=29.5154185022026, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323526, Length=249, Percent_Identity=26.9076305220884, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641702, Length=238, Percent_Identity=23.5294117647059, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 26732; Mature: 26732

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS01183 UBIE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVNLLEPLNGENWADLCCGTGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH
LAFLISERVSPSGSITGIDSAEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHH
CMSYGLRNLNNVEEGIKKVFDLLKDKGRAGFLDFNHSTRNSLSNIFQKIYLRLIVVTISR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLGPEYAYIEKSISNFPKKNELINIAKEVGFKKAEYRTILGGQMGILILTK
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVNLLEPLNGENWADLCCGTGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH
LAFLISERVSPSGSITGIDSAEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHH
CMSYGLRNLNNVEEGIKKVFDLLKDKGRAGFLDFNHSTRNSLSNIFQKIYLRLIVVTISR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLGPEYAYIEKSISNFPKKNELINIAKEVGFKKAEYRTILGGQMGILILTK
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]