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The map label for this gene is lytB [H]

Identifier: 123967823

GI number: 123967823

Start: 264180

End: 265376

Strand: Direct

Name: lytB [H]

Synonym: A9601_02861

Alternate gene names: 123967823

Gene position: 264180-265376 (Clockwise)

Preceding gene: 123967822

Following gene: 123967824

Centisome position: 15.82

GC content: 33.08

Gene sequence:

>1197_bases
ATGGATACTCAAGCTTTTAGAAGATCTCTTCATCATTCTGATAGATACAATAGAAGGGGTTTCGATTCTCCAACAAAAAG
AGCTCAAGCGTTAGAAGAAGCTTACCAAAGTGATTTGATAAGTTCTATCAGAGATAATGGTTTTACTTATACTAAAGGCA
GACTAAATATAAAGTTGGCCCAAGCCTTCGGTTTCTGTTGGGGAGTTGAAAGAGCTGTAGCAATGGCTTATGAAACCAGA
AGACATTACCCTAATGAGAATATTTGGATAACAAACGAAATAATTCATAATCCCTCGGTTAATGATCATTTAAGAAAAAT
GAATGTGAAATTCATTTCAGCTAAAAATGGAATCAAAGATTTTTCTTTAGTTTCTAATGGAGATGTTGTTATACTTCCTG
CTTTTGGAGCGACTGTTCAAGAAATGAAACTCTTACATGAGAAAGGTTGTCATATTATTGATACAACATGTCCATGGGTT
TCTAAGGTTTGGCATACGGTTGAAAAACATAAAAAACATGTTTTCACATCTATAATTCATGGAAAATTTAAGCATGAAGA
GACTCTTGCTACAAGTTCATTTGCAGGTAAATATTTAGTTGTACTTGATCTAGAAGAAGCAAACTACGTATCTGAATACA
TTCTGGGGAAAGGAAATAGAAATGAGTTTATGAATAAATTCTCTAAAGCTTTTTCTAATGGATTTGATCCTGATAAAGAT
TTAGATAGAGTGGGTGTTGCAAATCAGACAACTATGCTTAAGAGCGAGACTGAGGAAATTGGTAAGGTCTTTGAAAGGAC
GATGTTAAAAAAATTTGGGCCAGAAAACTTAAATAGTCACTTCTTAGCTTTTAATACTATTTGTGATGCAACTGAAGAAA
GACAAGATGCAATGTTCTCTTTGGTTGATGAAGACCTTGATATTTTAGTAGTTATTGGAGGCTTCAATTCTTCCAATACT
ACTCACTTACAGGAAATAGCAATTACTAAAAATATTTCTTCTTTTCATATTGATACGCCTGAGAGAATATCAGTTAAAGA
AAACTCAATATTTCACAAGCCATTAGGATCAGAATTAGAACTTAAAAAAAATTTTCTACCTAGTGGAAAAATTAATGTTG
GAATTACCTCAGGTGCTTCCACTCCTGATAAGGTCGTGGCAGATGTTATTGAAAAGTTAATTGATATTGCTTCCTGA

Upstream 100 bases:

>100_bases
TCTGCTAAATAATCTAACTAAAAATTAATTTAAGAAACCTGACTTATGTCAGGTTTCTTTTTTTTACGAAAAATTATTTA
AAACGTTGTAATATAGGAAA

Downstream 100 bases:

>100_bases
ATTTGTTATTCATTTATAAATTTGCTTAGTTTTTTAAATTTATTAGTCAGATAATTCCAAAAGATCAACTTTATTAACTA
GAATAATGAAAACTTAATGA

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYTKGRLNIKLAQAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYVSEYILGKGNRNEFMNKFSKAFSNGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFERTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNISSFHIDTPERISVKENSIFHKPLGSELELKKNFLPSGKINVGITSGASTPDKVVADVIEKLIDIAS

Sequences:

>Translated_398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYTKGRLNIKLAQAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYVSEYILGKGNRNEFMNKFSKAFSNGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFERTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNISSFHIDTPERISVKENSIFHKPLGSELELKKNFLPSGKINVGITSGASTPDKVVADVIEKLIDIAS
>Mature_398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYTKGRLNIKLAQAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYVSEYILGKGNRNEFMNKFSKAFSNGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFERTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNISSFHIDTPERISVKENSIFHKPLGSELELKKNFLPSGKINVGITSGASTPDKVVADVIEKLIDIAS

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=344, Percent_Identity=25.8720930232558, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 44964; Mature: 44964

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYTKGRLNIKLA
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEHH
QAFGFCWGVERAVAMAYETRRHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHEECCCCHHHHHHHHCEEEEECCCCCCC
FSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWVSKVWHTVEKHKKHVFTSIIH
CEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKFKHEETLATSSFAGKYLVVLDLEEANYVSEYILGKGNRNEFMNKFSKAFSNGFDPDKD
HHHCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
LDRVGVANQTTMLKSETEEIGKVFERTMLKKFGPENLNSHFLAFNTICDATEERQDAMFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
LVDEDLDILVVIGGFNSSNTTHLQEIAITKNISSFHIDTPERISVKENSIFHKPLGSELE
HHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEECCCCCCEEECCCCEECCCCCCCHH
LKKNFLPSGKINVGITSGASTPDKVVADVIEKLIDIAS
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYTKGRLNIKLA
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEHH
QAFGFCWGVERAVAMAYETRRHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHEECCCCHHHHHHHHCEEEEECCCCCCC
FSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWVSKVWHTVEKHKKHVFTSIIH
CEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKFKHEETLATSSFAGKYLVVLDLEEANYVSEYILGKGNRNEFMNKFSKAFSNGFDPDKD
HHHCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
LDRVGVANQTTMLKSETEEIGKVFERTMLKKFGPENLNSHFLAFNTICDATEERQDAMFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
LVDEDLDILVVIGGFNSSNTTHLQEIAITKNISSFHIDTPERISVKENSIFHKPLGSELE
HHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEECCCCCCEEECCCCEECCCCCCCHH
LKKNFLPSGKINVGITSGASTPDKVVADVIEKLIDIAS
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA