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The map label for this gene is mraW [H]

Identifier: 123967726

GI number: 123967726

Start: 174865

End: 175767

Strand: Reverse

Name: mraW [H]

Synonym: A9601_01891

Alternate gene names: 123967726

Gene position: 175767-174865 (Counterclockwise)

Preceding gene: 123967729

Following gene: 123967724

Centisome position: 10.53

GC content: 32.23

Gene sequence:

>903_bases
ATGCAAACTGACCTATCTGATTCATCTTTTTTCAATCATCAATCAGTTATGACAGATGAGATTATGGCCTCATTAGAGCA
TTACCCACTGATACATAACAATCAACTAAAGGGAATAGACGCAACTTTAGGTGGTGGCGGGCACTCTTATCATTTATTGA
GAAAATATTCGGATTTAAATATAATTGGACTTGATCAAGATCCATTCGCGAGAAAATCAGCATCAAAAAAACTTGATGAG
TTTAAAAACAGGATTGATATAAGGGCTTCAAATTTTGCGGATTTTGTACCAAAAGAAAAAGTTTCTTTTGTGATTGCAGA
TCTTGGAGTAAATAGTAACCAAATTGATGACCCTAAAAGAGGATTTAGTTTCCAGAAAGATGGTCCACTTGATATGCGCA
TGAATCCTTTTCTTGATGTTGATGCAGATAAATTAATTGAGGCTTTAAATGAAAAAGATCTAGCTAACCTAATCTATAAA
TACGGAGAGGAGAGATTATCAAGAAAGATTGCTAGAAAAATAAAATTGGATTTGAAGGAAAATGGGAAATATTCTGGAAC
AAAAGAGTTAGCTTATTCTATTGCAGGCTGCTTCCCACCAAAACAAAGATATAAAAAAATACATCCAGCAACAAGAACAT
TTCAAGCACTAAGAATTGCTGTTAATAAAGAAATTGAAGTATTAGAAAAATTTTTGCAAGTTGTACCTGAATGGCTTTTG
CCAGGGGGTATTATTTCTATTATTAGTTTTCATTCCCTTGAGGATAGATTAGTTAAGAGTTGTTTTAAGAATGATCAAAG
ACTAAAAAACCTGACAAAAAAGCCAATAACTCCTTCCGAACAAGAAATTGAACTAAATAAAAGAGCTAGAAGTGGAAAAT
TAAGAATTGCTCAATTAAATTAA

Upstream 100 bases:

>100_bases
GAGGGATGGTGAGGGCCAAAATTGACCACCATTGGTTCTGTTCTAGTCTCTAGCTGAGCCATTCCAAATTTAACTTCTAC
ACAAATCTTAGTCGAAAGTT

Downstream 100 bases:

>100_bases
AAGCAAATATTTTCCTATCGTAATGATCTGATCGTATTTGTAAGAATATGAATTGCTTGTTTTATATCTTTTGAATTAGT
ACTTAATCCAATACTTAGCC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MQTDLSDSSFFNHQSVMTDEIMASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLNIIGLDQDPFARKSASKKLDE
FKNRIDIRASNFADFVPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLDVDADKLIEALNEKDLANLIYK
YGEERLSRKIARKIKLDLKENGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQVVPEWLL
PGGIISIISFHSLEDRLVKSCFKNDQRLKNLTKKPITPSEQEIELNKRARSGKLRIAQLN

Sequences:

>Translated_300_residues
MQTDLSDSSFFNHQSVMTDEIMASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLNIIGLDQDPFARKSASKKLDE
FKNRIDIRASNFADFVPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLDVDADKLIEALNEKDLANLIYK
YGEERLSRKIARKIKLDLKENGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQVVPEWLL
PGGIISIISFHSLEDRLVKSCFKNDQRLKNLTKKPITPSEQEIELNKRARSGKLRIAQLN
>Mature_300_residues
MQTDLSDSSFFNHQSVMTDEIMASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLNIIGLDQDPFARKSASKKLDE
FKNRIDIRASNFADFVPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLDVDADKLIEALNEKDLANLIYK
YGEERLSRKIARKIKLDLKENGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQVVPEWLL
PGGIISIISFHSLEDRLVKSCFKNDQRLKNLTKKPITPSEQEIELNKRARSGKLRIAQLN

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=343, Percent_Identity=33.5276967930029, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI165377202, Length=177, Percent_Identity=35.5932203389831, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786270, Length=314, Percent_Identity=38.2165605095541, Blast_Score=182, Evalue=3e-47,
Organism=Drosophila melanogaster, GI62472493, Length=304, Percent_Identity=33.8815789473684, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571637, Length=304, Percent_Identity=33.8815789473684, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34222; Mature: 34222

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS01048 RIBOSOMAL_S6

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDLSDSSFFNHQSVMTDEIMASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLN
CCCCCCCCHHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCHHHHHHHCCCCE
IIGLDQDPFARKSASKKLDEFKNRIDIRASNFADFVPKEKVSFVIADLGVNSNQIDDPKR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHEEEEEECCCCCCCCCCHHH
GFSFQKDGPLDMRMNPFLDVDADKLIEALNEKDLANLIYKYGEERLSRKIARKIKLDLKE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
NGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQVVPEWLL
CCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PGGIISIISFHSLEDRLVKSCFKNDQRLKNLTKKPITPSEQEIELNKRARSGKLRIAQLN
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MQTDLSDSSFFNHQSVMTDEIMASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLN
CCCCCCCCHHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCHHHHHHHCCCCE
IIGLDQDPFARKSASKKLDEFKNRIDIRASNFADFVPKEKVSFVIADLGVNSNQIDDPKR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHEEEEEECCCCCCCCCCHHH
GFSFQKDGPLDMRMNPFLDVDADKLIEALNEKDLANLIYKYGEERLSRKIARKIKLDLKE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
NGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQVVPEWLL
CCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PGGIISIISFHSLEDRLVKSCFKNDQRLKNLTKKPITPSEQEIELNKRARSGKLRIAQLN
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA