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The map label for this gene is aroK [H]

Identifier: 123967661

GI number: 123967661

Start: 121889

End: 122446

Strand: Direct

Name: aroK [H]

Synonym: A9601_01241

Alternate gene names: 123967661

Gene position: 121889-122446 (Clockwise)

Preceding gene: 123967655

Following gene: 123967663

Centisome position: 7.3

GC content: 29.03

Gene sequence:

>558_bases
ATGGAACAAACCATTATCAAAAAAACAGTTCTTACTTTAAAGGGCAGAAGCATATTTTTAATAGGAATGATGGGTTCAGG
CAAGTCAAAAACTGGTTTGAAGTTGGCTGAATTATTGAAGTATAAATACATTGATTTAGATTCATTAATAGAGAAGTTGG
CAAAAAAATCTATTAATCAAATTTTTAATGATGAAGGAGAAGAGAAATTCCGTGAATTAGAAGCAAACTGCCTTAAAGAA
ACTATCAAAATTCCTTCATTAGTAATCTCAACTGGGGGAGGAATAGTTACCAAATCGGAAAACTGGGGAATCTTAAGACA
GGGAATAATTGCTTGGATAGATCTAGACAAAGATATAGCAATTGAAAGATTGAAAAATGAAATTGAAAATAGACCACTTC
TTCAGGGAAAGAATCTAAATGATTTATATATGAGCATTTTTCAATCTAGAGAAAATTTGTATTCTCAAGCAGATTTAAGA
ATTCAAGTAAAAAGGGAAAATATTGAAGAAGTAGCTATGAAAATAATTAATGCAATTCATAAAGAAATAATTAGTTAA

Upstream 100 bases:

>100_bases
ACGCATTCACGTCCTTTTCCATGTAATGGTTTGGATTGTGTAGAAGTCATACCTTTCTGCGATAATACTATCTTAAGGTT
TTAAATACGCTTTTGTCTTT

Downstream 100 bases:

>100_bases
TCTGGTTCAATTCTTACTGCAAACCATTTGATAACGTATCCTAATTTTATTTCTAATTCATAAGTGCTTTCTAATAATTC
TTCAAAAAATTCCTGATCAG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MEQTIIKKTVLTLKGRSIFLIGMMGSGKSKTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEEKFRELEANCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSIFQSRENLYSQADLR
IQVKRENIEEVAMKIINAIHKEIIS

Sequences:

>Translated_185_residues
MEQTIIKKTVLTLKGRSIFLIGMMGSGKSKTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEEKFRELEANCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSIFQSRENLYSQADLR
IQVKRENIEEVAMKIINAIHKEIIS
>Mature_185_residues
MEQTIIKKTVLTLKGRSIFLIGMMGSGKSKTGLKLAELLKYKYIDLDSLIEKLAKKSINQIFNDEGEEKFRELEANCLKE
TIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIAIERLKNEIENRPLLQGKNLNDLYMSIFQSRENLYSQADLR
IQVKRENIEEVAMKIINAIHKEIIS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=31.5151515151515, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786587, Length=144, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21107; Mature: 21107

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTIIKKTVLTLKGRSIFLIGMMGSGKSKTGLKLAELLKYKYIDLDSLIEKLAKKSINQ
CCCHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IFNDEGEEKFRELEANCLKETIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIA
HHCCCHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCHHHHHHHHEEECCHHHH
IERLKNEIENRPLLQGKNLNDLYMSIFQSRENLYSQADLRIQVKRENIEEVAMKIINAIH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
KEIIS
HHHCC
>Mature Secondary Structure
MEQTIIKKTVLTLKGRSIFLIGMMGSGKSKTGLKLAELLKYKYIDLDSLIEKLAKKSINQ
CCCHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IFNDEGEEKFRELEANCLKETIKIPSLVISTGGGIVTKSENWGILRQGIIAWIDLDKDIA
HHCCCHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCHHHHHHHHEEECCHHHH
IERLKNEIENRPLLQGKNLNDLYMSIFQSRENLYSQADLRIQVKRENIEEVAMKIINAIH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
KEIIS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA