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The map label for this gene is rimO [H]

Identifier: 123967655

GI number: 123967655

Start: 117120

End: 118484

Strand: Direct

Name: rimO [H]

Synonym: A9601_01181

Alternate gene names: 123967655

Gene position: 117120-118484 (Clockwise)

Preceding gene: 123967653

Following gene: 123967661

Centisome position: 7.01

GC content: 31.72

Gene sequence:

>1365_bases
GTGAAACAAAATAGTCTCAATGTAAAAGAAAAAAAACTATCTAAGGTTGCATTCAGTCATGTTGGCTGTGAGAAAAATCT
TGTTGATACTGAACATATGCAAGGCTTATTAGATAAAGAGGGTTATGAAGTTGACAGCAATATAAATGATGCAAATGTTG
TTGTTGTAAATACTTGCAGTTTTATTGAAACAGCTAGAGAAGAATCTATAAGAAAAATTCTAGAATATACAAATCAAGGA
AAGGAAGTAATAGTTGCAGGCTGTATGGCTCAGCATTTTAAAGATGAGCTTATAAGAGAAATCCCTGAAATAAAAGGTTT
GGTTGGAACAGGAGATTATCAAAAGATAGCCAAGGTTTTAGACAGAGTAGAACAAGGGGAAATCGTTAATGAAGTTTCAA
AAATACCCGAATTTATCGCAGATGAGGAAATGCCTCGTTTTGTAGATAAAAATAAATTTGTTGCTTATCTTCGCATCGCT
GAAGGCTGCAACTACAATTGCGCTTTTTGTATTATTCCTAAGTTGAGAGGTCCTCAAAGAAGTAGAACAATAGAATCTAT
AGTATCAGAAGCCAAAAGTCTTGCAAAAAAGGGTATTCAAGAAATCATATTAATTAGTCAAATAACAACTAATTATGGTC
AAGATATTTATGGAAAACCATCATTAGCCAAACTTTTGAATGAGCTTTCTAAAGTTTCAATTCCTTGGATAAGGATACAT
TATGCTTATCCAACAGGTTTAACTGATGAAGTTATTAGAGCTTTCAAAGATTCAAAGAATATAGTACCTTACTTTGATTT
GCCACTTCAGCATAGTCATCCCGATGTGTTGAAGAGTATGAATAGACCTTGGCAAGCTTCTTTGAATGAATCAATTTTGG
AGAAAATTAGAGAAGAAATTCCATCTGCTGTGTTAAGAACTAGTCTCATTGTTGGTTTCCCAGGAGAAAAAAAAGAACAT
TTTGAACATCTTCTCCAATTTTTGGATAGGCACAAATTTGATCATGTTGGAGTGTTTATTTTTTCTCCTGAGGAAGGAAC
TACAGCTTTTCATTTACCAAATAAAGTATCTCTAGAGGTTGCAGAGGCAAGAAAAGATAACGTTATTTCAGTTCAACAAA
ATATCTCTAAAGATAAAAATCAGACATATGTTGGTTCAAAAATGAAGATTTTGGTAGAAAAAATATCAGACAATAACGAA
TTAATAGGTCGGTCCTATAATTTCGCTCCTGAAATTGATGGAACTGTAATTTTATCTGTTAAAGATAAAATTGATTTGAA
AAATTATATTGGTAAATTTGTTGAAGCAAATATTACTTTTGCAGATGAATATGATTTGTATGGTGAGATTATTAAAATTT
TGTAG

Upstream 100 bases:

>100_bases
AAGAAGGTTTGTTATTTACATTATCTATCCTAATATTATCTTGGCATGAGAGTTATATACGAAATGCTGTTTAAATCTTT
TAATTCTTATTTTTTAAGTT

Downstream 100 bases:

>100_bases
TTTTTTAAATTAATTTAACTGCTCTTAAGAGCTTATCTAATGCGAAAGCAGCTCCAAAACCAAAACCAATAAATGCAAAA
TAGAAAATGATGTTCATTAA

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINDANVVVVNTCSFIETAREESIRKILEYTNQG
KEVIVAGCMAQHFKDELIREIPEIKGLVGTGDYQKIAKVLDRVEQGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIA
EGCNYNCAFCIIPKLRGPQRSRTIESIVSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVSIPWIRIH
YAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEH
FEHLLQFLDRHKFDHVGVFIFSPEEGTTAFHLPNKVSLEVAEARKDNVISVQQNISKDKNQTYVGSKMKILVEKISDNNE
LIGRSYNFAPEIDGTVILSVKDKIDLKNYIGKFVEANITFADEYDLYGEIIKIL

Sequences:

>Translated_454_residues
MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINDANVVVVNTCSFIETAREESIRKILEYTNQG
KEVIVAGCMAQHFKDELIREIPEIKGLVGTGDYQKIAKVLDRVEQGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIA
EGCNYNCAFCIIPKLRGPQRSRTIESIVSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVSIPWIRIH
YAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEH
FEHLLQFLDRHKFDHVGVFIFSPEEGTTAFHLPNKVSLEVAEARKDNVISVQQNISKDKNQTYVGSKMKILVEKISDNNE
LIGRSYNFAPEIDGTVILSVKDKIDLKNYIGKFVEANITFADEYDLYGEIIKIL
>Mature_454_residues
MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINDANVVVVNTCSFIETAREESIRKILEYTNQG
KEVIVAGCMAQHFKDELIREIPEIKGLVGTGDYQKIAKVLDRVEQGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIA
EGCNYNCAFCIIPKLRGPQRSRTIESIVSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVSIPWIRIH
YAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEH
FEHLLQFLDRHKFDHVGVFIFSPEEGTTAFHLPNKVSLEVAEARKDNVISVQQNISKDKNQTYVGSKMKILVEKISDNNE
LIGRSYNFAPEIDGTVILSVKDKIDLKNYIGKFVEANITFADEYDLYGEIIKIL

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=486, Percent_Identity=28.3950617283951, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI28872782, Length=486, Percent_Identity=28.3950617283951, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI93277076, Length=453, Percent_Identity=24.2825607064018, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787057, Length=446, Percent_Identity=39.6860986547085, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1786882, Length=447, Percent_Identity=27.7404921700224, Blast_Score=162, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553146, Length=471, Percent_Identity=25.0530785562633, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71996771, Length=290, Percent_Identity=26.551724137931, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356207, Length=424, Percent_Identity=26.4150943396226, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI19922432, Length=454, Percent_Identity=25.3303964757709, Blast_Score=124, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR012340
- InterPro:   IPR007197
- InterPro:   IPR005840
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51523; Mature: 51523

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINDANVVVVNTCS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECHH
FIETAREESIRKILEYTNQGKEVIVAGCMAQHFKDELIREIPEIKGLVGTGDYQKIAKVL
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
DRVEQGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIAEGCNYNCAFCIIPKLRGPQR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCHH
SRTIESIVSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVSIPWIRIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
YAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEI
EECCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHH
PSAVLRTSLIVGFPGEKKEHFEHLLQFLDRHKFDHVGVFIFSPEEGTTAFHLPNKVSLEV
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEEE
AEARKDNVISVQQNISKDKNQTYVGSKMKILVEKISDNNELIGRSYNFAPEIDGTVILSV
HHCCCCCEEEHHHHCCCCCCCEECCCHHHHHHHHHCCCCCEECCCCCCCCCCCCEEEEEE
KDKIDLKNYIGKFVEANITFADEYDLYGEIIKIL
CCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHC
>Mature Secondary Structure
MKQNSLNVKEKKLSKVAFSHVGCEKNLVDTEHMQGLLDKEGYEVDSNINDANVVVVNTCS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECHH
FIETAREESIRKILEYTNQGKEVIVAGCMAQHFKDELIREIPEIKGLVGTGDYQKIAKVL
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
DRVEQGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIAEGCNYNCAFCIIPKLRGPQR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCHH
SRTIESIVSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVSIPWIRIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
YAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEI
EECCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHH
PSAVLRTSLIVGFPGEKKEHFEHLLQFLDRHKFDHVGVFIFSPEEGTTAFHLPNKVSLEV
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEEE
AEARKDNVISVQQNISKDKNQTYVGSKMKILVEKISDNNELIGRSYNFAPEIDGTVILSV
HHCCCCCEEEHHHHCCCCCCCEECCCHHHHHHHHHCCCCCEECCCCCCCCCCCCEEEEEE
KDKIDLKNYIGKFVEANITFADEYDLYGEIIKIL
CCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA