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The map label for this gene is dhsS

Identifier: 123967571

GI number: 123967571

Start: 32388

End: 33551

Strand: Reverse

Name: dhsS

Synonym: A9601_00341

Alternate gene names: NA

Gene position: 33551-32388 (Counterclockwise)

Preceding gene: 123967574

Following gene: 123967569

Centisome position: 2.01

GC content: 32.9

Gene sequence:

>1164_bases
GTGGCCATACAACAAAAATTATCATTGATGATTCCTGGACCCACACCAGTTCCAGAAAAAGTATTACAAGCATTAAGTAA
ACATCCAATAGGCCATCGCAGCAAAGAATTCCAAGATCTCGTAGAGAGTACTACTAAAAATTTACAATGGCTTCATCAAA
CTCAAAATGATGTTCTAACAATTACTGGAAGTGGGACTGCCGCAATGGAGGCCGGAATAATAAATACCTTAAGTAGAGGA
GATAAAGTAATTTGTGGAGACAATGGAAAATTTGGAGAAAGATGGGTAAAAGTTGCTAAAGAATTTGGTCTAGAAGTAAT
AAAAATTGATTCAGAATGGGGTACTCCACTTGATCCAGAAAAATTCAAAAAGGTATTAGAAGAAGATACACAAAAAGAAA
TTAAAGCTGTTATTTTGACTCATTCTGAAACCTCAACAGGTGTAATTAATGACTTAAAAACCATAAGTTCATATATTCGC
AAACACAATACAGCTTTATCAATTGTTGATTGCGTTACAAGTCTTGGAGCTTGCAATGTTCCAGTAGATGAATGGGAATT
AGATATCGTTGCTTCAGGATCACAAAAAGGTTATATGATACCTCCAGGGCTTAGTTTTATAGCAATGAGCCAAAAAGCAT
GGGAAGCTGCAGAAAAATCTAATCTACCAAAATTTTATTTAAATTTAAAATCATACAAAAAAAGTCTTTTAAGTAACAGT
AACCCATATACTCCAGCAGTTAATTTGGTTTTTGCTTTAGATGAATCTTTAAAAATGATGAAAGAAGAAGGCTTAGATAA
CATTTTCTTCAGACACAATAAACATAAATTAGCAATGAGCAATGCTGTAAAGGCTTTAGATCTTAAATTATTTGCTGATG
AAAAATACTTGAGCCCATCAATTACTGCGGTAAAAACTGAAGGAATAGATGCTGAAGAATTTAGGAAAACTATAAAAAAT
AATTTTGATATTTTACTTGCTGGTGGTCAAGATCATATGAAAGGAAAAATATTTAGAGTCGGGCACTTAGGTTATGTTAA
TGATAGAGATATTATTACGGTGGTTTCTGCTATAAGTAATACACTTCTCAACCTCGGTAAAATTACAGCCAAACAAGCTG
GTGAAGCATTAAAAGTTGCTTCAAGATATCTAGCAGAGAATTAA

Upstream 100 bases:

>100_bases
CTCCAGCAACCCACAAAGGTAAAGAAAATCCTTTTTTCAAATCAAGTAATTGAAAAATATATAATGAGAACTAATCTAAG
AATGACCTATTTATCAAAAA

Downstream 100 bases:

>100_bases
GTTAAGTTCCTGGCTCTTCAATATTTCCGCCTAATTCAACAATCTTTTTTCTAAGAACAATTGATTTTTTTTCATCACCG
TTGGTTTGTGCGATTGCAAG

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVESTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRG
DKVICGDNGKFGERWVKVAKEFGLEVIKIDSEWGTPLDPEKFKKVLEEDTQKEIKAVILTHSETSTGVINDLKTISSYIR
KHNTALSIVDCVTSLGACNVPVDEWELDIVASGSQKGYMIPPGLSFIAMSQKAWEAAEKSNLPKFYLNLKSYKKSLLSNS
NPYTPAVNLVFALDESLKMMKEEGLDNIFFRHNKHKLAMSNAVKALDLKLFADEKYLSPSITAVKTEGIDAEEFRKTIKN
NFDILLAGGQDHMKGKIFRVGHLGYVNDRDIITVVSAISNTLLNLGKITAKQAGEALKVASRYLAEN

Sequences:

>Translated_387_residues
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVESTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRG
DKVICGDNGKFGERWVKVAKEFGLEVIKIDSEWGTPLDPEKFKKVLEEDTQKEIKAVILTHSETSTGVINDLKTISSYIR
KHNTALSIVDCVTSLGACNVPVDEWELDIVASGSQKGYMIPPGLSFIAMSQKAWEAAEKSNLPKFYLNLKSYKKSLLSNS
NPYTPAVNLVFALDESLKMMKEEGLDNIFFRHNKHKLAMSNAVKALDLKLFADEKYLSPSITAVKTEGIDAEEFRKTIKN
NFDILLAGGQDHMKGKIFRVGHLGYVNDRDIITVVSAISNTLLNLGKITAKQAGEALKVASRYLAEN
>Mature_386_residues
AIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVESTTKNLQWLHQTQNDVLTITGSGTAAMEAGIINTLSRGD
KVICGDNGKFGERWVKVAKEFGLEVIKIDSEWGTPLDPEKFKKVLEEDTQKEIKAVILTHSETSTGVINDLKTISSYIRK
HNTALSIVDCVTSLGACNVPVDEWELDIVASGSQKGYMIPPGLSFIAMSQKAWEAAEKSNLPKFYLNLKSYKKSLLSNSN
PYTPAVNLVFALDESLKMMKEEGLDNIFFRHNKHKLAMSNAVKALDLKLFADEKYLSPSITAVKTEGIDAEEFRKTIKNN
FDILLAGGQDHMKGKIFRVGHLGYVNDRDIITVVSAISNTLLNLGKITAKQAGEALKVASRYLAEN

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=357, Percent_Identity=31.0924369747899, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17536281, Length=374, Percent_Identity=29.9465240641711, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321079, Length=366, Percent_Identity=26.775956284153, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17530823, Length=374, Percent_Identity=26.7379679144385, Blast_Score=145, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42761; Mature: 42630

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVESTTKNLQWLHQTQNDVLT
CCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIINTLSRGDKVICGDNGKFGERWVKVAKEFGLEVIKIDSEWGTPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHH
KFKKVLEEDTQKEIKAVILTHSETSTGVINDLKTISSYIRKHNTALSIVDCVTSLGACNV
HHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PVDEWELDIVASGSQKGYMIPPGLSFIAMSQKAWEAAEKSNLPKFYLNLKSYKKSLLSNS
CCCCEEEEEEECCCCCCEECCCCCHHEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
NPYTPAVNLVFALDESLKMMKEEGLDNIFFRHNKHKLAMSNAVKALDLKLFADEKYLSPS
CCCCHHHHEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCC
ITAVKTEGIDAEEFRKTIKNNFDILLAGGQDHMKGKIFRVGHLGYVNDRDIITVVSAISN
CEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
TLLNLGKITAKQAGEALKVASRYLAEN
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIQQKLSLMIPGPTPVPEKVLQALSKHPIGHRSKEFQDLVESTTKNLQWLHQTQNDVLT
CCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIINTLSRGDKVICGDNGKFGERWVKVAKEFGLEVIKIDSEWGTPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHH
KFKKVLEEDTQKEIKAVILTHSETSTGVINDLKTISSYIRKHNTALSIVDCVTSLGACNV
HHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PVDEWELDIVASGSQKGYMIPPGLSFIAMSQKAWEAAEKSNLPKFYLNLKSYKKSLLSNS
CCCCEEEEEEECCCCCCEECCCCCHHEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
NPYTPAVNLVFALDESLKMMKEEGLDNIFFRHNKHKLAMSNAVKALDLKLFADEKYLSPS
CCCCHHHHEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCC
ITAVKTEGIDAEEFRKTIKNNFDILLAGGQDHMKGKIFRVGHLGYVNDRDIITVVSAISN
CEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
TLLNLGKITAKQAGEALKVASRYLAEN
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129525 [H]