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The map label for this gene is pdxA [H]

Identifier: 123967564

GI number: 123967564

Start: 28262

End: 29296

Strand: Reverse

Name: pdxA [H]

Synonym: A9601_00271

Alternate gene names: 123967564

Gene position: 29296-28262 (Counterclockwise)

Preceding gene: 123967565

Following gene: 123967561

Centisome position: 1.75

GC content: 33.43

Gene sequence:

>1035_bases
ATGAATTTTCAAAATACAAATAAACCATTAAAGGTAGTAATAAGCGTAGGAGATGAGTCAGGTATTGGACCCGAAATAAT
CTTAAAAGCACTTTGTTCTAATGAGATATCAGAAAATATTGAATTTAAGTTAGTTGGATCAAAAAAAAATTTACAAAATA
CATATGAACATCTTAGATCCTTAGGATTAGAAAACCTTGCAAATCCTAAAAATTTAAAGGTAATAGATCTCGAGATTTCT
CCATCAAATAATAACCCTAAATCAAATTATGGTGATTCAAGTTTCCAATATTTAAAAAAAGCAATTGAAATTGTAAAACA
ATATCCCAACTCAGCGCTAGTAACTGGGCCAATTTGCAAGAAATCATGGTCTCTAGCAGGGCATTACTTCTCTGGTCAAA
CCGAAGTACTAGCAAAATCATGTGGAGTAAAAAACGTTGGAATGTTATTCACAGCAAAATCACCAATTACAGGTTGGAGA
TTTAATACTTTACTAGCTACAACCCACATAGCACTTTGTGAGGTTCCAAAGATATTAACTACAGAATTAATACACTCTAA
ATTAGACCTTTTCAAAGATTTTTGTAATACCTTTATTGATAAACCTACTTTAAAAGTAGCAGGGCTGAACCCCCATGCCG
GCGAAGAGGGCATTTTAGGTCATGAAGAAAAAGATTGGCTTAATGACGCATTAATTACTTGGAGTAACAAGAATAGAGAT
ATAAAATTATTAGGACCTTTATCACCAGATAGTTGCTGGAATTCTTCCGTAAAAGCCTGGAGTGACAAAAATGCTGAAAA
GCATGATGGCATTCTTGCTATGTATCATGATCAAGGTTTAATACCAATGAAAGTCATAGCTTTTAATTACTCAGTCAATA
CCACAATCGGTTTACCCTTTATAAGAACATCTCCAGATCATGGAACGGGATTTGATATTGCTGGCAAAGGAATTGCTCAA
TCTCAAAGCATGATTGAGGCTATAAAGACTGCAATAGAAATGACTAAAAATTCAAGATTGCTTAACACGCATTAG

Upstream 100 bases:

>100_bases
TTTTATGCGAAACACTTGGATATAAGCTAATTTATAAAAACTATAAAATAGGCTTAAAAAACTGTTACCTAAATAGATAA
AAATATATTTAAAACTTTTT

Downstream 100 bases:

>100_bases
AACTTGACCAAATTCAACTGGCGTCCCATTTTCAACGAGAATCTCTACAATTTCAGCATTAAATTCAGATTCAATTTCAT
TCATTAACTTCATTGCTTCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNFQNTNKPLKVVISVGDESGIGPEIILKALCSNEISENIEFKLVGSKKNLQNTYEHLRSLGLENLANPKNLKVIDLEIS
PSNNNPKSNYGDSSFQYLKKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWR
FNTLLATTHIALCEVPKILTTELIHSKLDLFKDFCNTFIDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSNKNRD
IKLLGPLSPDSCWNSSVKAWSDKNAEKHDGILAMYHDQGLIPMKVIAFNYSVNTTIGLPFIRTSPDHGTGFDIAGKGIAQ
SQSMIEAIKTAIEMTKNSRLLNTH

Sequences:

>Translated_344_residues
MNFQNTNKPLKVVISVGDESGIGPEIILKALCSNEISENIEFKLVGSKKNLQNTYEHLRSLGLENLANPKNLKVIDLEIS
PSNNNPKSNYGDSSFQYLKKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWR
FNTLLATTHIALCEVPKILTTELIHSKLDLFKDFCNTFIDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSNKNRD
IKLLGPLSPDSCWNSSVKAWSDKNAEKHDGILAMYHDQGLIPMKVIAFNYSVNTTIGLPFIRTSPDHGTGFDIAGKGIAQ
SQSMIEAIKTAIEMTKNSRLLNTH
>Mature_344_residues
MNFQNTNKPLKVVISVGDESGIGPEIILKALCSNEISENIEFKLVGSKKNLQNTYEHLRSLGLENLANPKNLKVIDLEIS
PSNNNPKSNYGDSSFQYLKKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWR
FNTLLATTHIALCEVPKILTTELIHSKLDLFKDFCNTFIDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSNKNRD
IKLLGPLSPDSCWNSSVKAWSDKNAEKHDGILAMYHDQGLIPMKVIAFNYSVNTTIGLPFIRTSPDHGTGFDIAGKGIAQ
SQSMIEAIKTAIEMTKNSRLLNTH

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=339, Percent_Identity=31.858407079646, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37939; Mature: 37939

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQNTNKPLKVVISVGDESGIGPEIILKALCSNEISENIEFKLVGSKKNLQNTYEHLRS
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
LGLENLANPKNLKVIDLEISPSNNNPKSNYGDSSFQYLKKAIEIVKQYPNSALVTGPICK
CCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHH
KSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEVPKILT
CCCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHH
TELIHSKLDLFKDFCNTFIDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSNKNRD
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCC
IKLLGPLSPDSCWNSSVKAWSDKNAEKHDGILAMYHDQGLIPMKVIAFNYSVNTTIGLPF
EEEECCCCCCHHCCCCCCCCCCCCCCHHCCEEEEEECCCCCEEEEEEEEEEECCEECCCE
IRTSPDHGTGFDIAGKGIAQSQSMIEAIKTAIEMTKNSRLLNTH
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure
MNFQNTNKPLKVVISVGDESGIGPEIILKALCSNEISENIEFKLVGSKKNLQNTYEHLRS
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
LGLENLANPKNLKVIDLEISPSNNNPKSNYGDSSFQYLKKAIEIVKQYPNSALVTGPICK
CCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHH
KSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRFNTLLATTHIALCEVPKILT
CCCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHH
TELIHSKLDLFKDFCNTFIDKPTLKVAGLNPHAGEEGILGHEEKDWLNDALITWSNKNRD
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHCCEEEEECCCCCC
IKLLGPLSPDSCWNSSVKAWSDKNAEKHDGILAMYHDQGLIPMKVIAFNYSVNTTIGLPF
EEEECCCCCCHHCCCCCCCCCCCCCCHHCCEEEEEECCCCCEEEEEEEEEEECCEECCCE
IRTSPDHGTGFDIAGKGIAQSQSMIEAIKTAIEMTKNSRLLNTH
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA