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The map label for this gene is gap2 [H]

Identifier: 123967559

GI number: 123967559

Start: 24082

End: 25104

Strand: Direct

Name: gap2 [H]

Synonym: A9601_00221

Alternate gene names: 123967559

Gene position: 24082-25104 (Clockwise)

Preceding gene: 123967555

Following gene: 123967562

Centisome position: 1.44

GC content: 37.34

Gene sequence:

>1023_bases
ATGACTTTGCGTGTTGCAATTAACGGCTTTGGCAGAATTGGTCGAAACTTTATGCGTTGTTGGCTTAGTAGAGGGGCTTA
CACCAATATTGAGGTAGTTGGGATTAATGTTACCTCTGATCCTAAGACTAATGCTCATTTATTGAAATATGACTCAGTCC
TTGGTCAACTGGATGGTGTTGATATTCAATACACTGACGATACTTTTGTAATTAATAACAAGACAATTAAATGTTTCTCT
GATAGAAACCCTATGAACCTCCCTTGGAAAGAATGGGGTGTAGATTTGGTTATTGAATCTACTGGAGTATTTAATACAGA
CGTAGGTGCAAGTAAGCACTTAGAGGTAGGAGCAAAAAAAGTAATCTTAACTGCTCCCGGTAAAGGCGATGGTGTTGGTA
CTTATGTAGTTGGAGTTAATGCTGATACATATAAACATAAAGATTATGATATTTTGAGTAATGCTAGTTGTACAACGAAC
TGTTTAGCTCCAGTAGTTAAAGTTTTAGACCAAACTTTTGGGATTAATAAAGGTTTGATGACTACAATTCATAGTTATAC
AGGGGATCAAAGAATTTTAGATAATAGTCATAGAGATCTAAGAAGGGCTAGAGCCGCAGCTACAAACATTGTTCCTACTT
CTACAGGAGCTGCAAAAGCAGTAGCTCTGGTATACCCAGAAATGAAAGGCAAATTAACAGGAATTGCAATGAGAGTTCCA
ACTCCTAATGTTTCAGCAGTAGATTTTGTTTTTGAATCTTCTAAATCTGTCACAGCTGAAGAAGTCAACACTGCTCTCAA
GGAAGCATCTTTAGGCTCAATGAAAGGAATTATTAAGTATGGAGATGAACCATTAGTTTCAAGCGATTATGCAGGTACCA
ATGAATCATCAATTGTAGATAGCGACCTCACTATGTGTATCGGCGACAATCTTGTTAAGGTCCTTGCTTGGTATGACAAC
GAGTGGGGCTATAGTCAAAGGGTTGTTGATTTAGCAGAGATTGTTGCTAAAAATTGGGAATAA

Upstream 100 bases:

>100_bases
AACTAGACTGATTTGCTTAATAAATTAAAAAAACCTTACGTTATTGCACAAAATTCAGTATGATCAGCAACTTAGGTTAA
TCATTTAGAAATTATTAGTT

Downstream 100 bases:

>100_bases
TTAAAAGTGCTTGAAAGGTATATTTTTCAATAAATGATTTTTATTTTTATCTTTAAATTCTATTGATGGTTTACCATTAA
CGAAATAACCAATCTCGTAA

Product: glyceraldehyde 3-phosphate dehydrogenase(NADP+)(phosphorylating)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFS
DRNPMNLPWKEWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADTYKHKDYDILSNASCTTN
CLAPVVKVLDQTFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
TPNVSAVDFVFESSKSVTAEEVNTALKEASLGSMKGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDN
EWGYSQRVVDLAEIVAKNWE

Sequences:

>Translated_340_residues
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFS
DRNPMNLPWKEWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADTYKHKDYDILSNASCTTN
CLAPVVKVLDQTFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
TPNVSAVDFVFESSKSVTAEEVNTALKEASLGSMKGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDN
EWGYSQRVVDLAEIVAKNWE
>Mature_339_residues
TLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFSD
RNPMNLPWKEWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADTYKHKDYDILSNASCTTNC
LAPVVKVLDQTFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVPT
PNVSAVDFVFESSKSVTAEEVNTALKEASLGSMKGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDNE
WGYSQRVVDLAEIVAKNWE

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=44.1087613293051, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=43.4131736526946, Blast_Score=267, Evalue=1e-71,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=48.2248520710059, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=43.3333333333333, Blast_Score=288, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=44.1520467836257, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=44.1520467836257, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=43.2748538011696, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=43.2748538011696, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=48.377581120944, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6322468, Length=340, Percent_Identity=47.6470588235294, Blast_Score=308, Evalue=8e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=47.0588235294118, Blast_Score=303, Evalue=2e-83,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=45.3453453453453, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=45.3453453453453, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=45.6456456456456, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=45.6456456456456, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=44.3768996960486, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37018; Mature: 36887

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCC
DIQYTDDTFVINNKTIKCFSDRNPMNLPWKEWGVDLVIESTGVFNTDVGASKHLEVGAKK
EEEECCCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCEE
VILTAPGKGDGVGTYVVGVNADTYKHKDYDILSNASCTTNCLAPVVKVLDQTFGINKGLM
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
TTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
HHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC
TPNVSAVDFVFESSKSVTAEEVNTALKEASLGSMKGIIKYGDEPLVSSDYAGTNESSIVD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCCCCCEEC
SDLTMCIGDNLVKVLAWYDNEWGYSQRVVDLAEIVAKNWE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCC
DIQYTDDTFVINNKTIKCFSDRNPMNLPWKEWGVDLVIESTGVFNTDVGASKHLEVGAKK
EEEECCCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCEE
VILTAPGKGDGVGTYVVGVNADTYKHKDYDILSNASCTTNCLAPVVKVLDQTFGINKGLM
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
TTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
HHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC
TPNVSAVDFVFESSKSVTAEEVNTALKEASLGSMKGIIKYGDEPLVSSDYAGTNESSIVD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCCCCCEEC
SDLTMCIGDNLVKVLAWYDNEWGYSQRVVDLAEIVAKNWE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]