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The map label for this gene is efp [H]

Identifier: 123967562

GI number: 123967562

Start: 27219

End: 27779

Strand: Direct

Name: efp [H]

Synonym: A9601_00251

Alternate gene names: 123967562

Gene position: 27219-27779 (Clockwise)

Preceding gene: 123967559

Following gene: 123967563

Centisome position: 1.63

GC content: 38.86

Gene sequence:

>561_bases
ATGATTTCCAGTAACGATTTTCGCACAGGTACAACCATCGAATTGGATGGACAAGTTTGGCGTGTTGTAGAATTTCTACA
TGTCAAGCCTGGTAAGGGTTCTGCTTTCGTGCGAACAAAATTAAAATCAGTTCAAAGCGGCAACGTGGTTGAAAAAACTT
TTCGAGCCGGAGAACAAGTACAGCAGGCTATCCTTGAGAAGTCTAACCTGCAACATACTTATGTGGAGTCTGGTGATTAT
GTTTTTATGGATATGACGAGTTTTGAAGAGACAAGTCTGACCTCTGAACAAATCGGTAAAGGTGCAAAGTATTTGAAAGA
GGGAATGGAGGTTAATGTAATTTTTCATAATGGTAAAGTTTTAGAAGTAGAACTTCCAATATCTATTACTTTGAAAGTTA
CAGAGACTGATCCTGGAGTTAAAGGCGATACTGCTAGTGGGGGCACAAAACCAGCTATTCTAGAGACAGGTGCTCAAGTT
ATGGTTCCTTTATTTATTTCTGTGGGAGAAATGATTAGAGTTGATACTCGTAATGACAGTTACCTAGGACGTGAAAATTA
A

Upstream 100 bases:

>100_bases
AATTGCGATTGATAGAATTAATAAAAGTTTGTTCTGATTTGATAAGAATTTTTGCATAGCACTCTTGCAGGTTTATGATC
CATGAGGATTTAATACAGGA

Downstream 100 bases:

>100_bases
TGGCTATGAAATTAGATCATGAAGACTTAAATCGCTTAATAGAGAAAATCTCTGCAAGTGATATACAAGAGTTCTCGCTA
GAGGGAGAAGATTTTAAACT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQSGNVVEKTFRAGEQVQQAILEKSNLQHTYVESGDY
VFMDMTSFEETSLTSEQIGKGAKYLKEGMEVNVIFHNGKVLEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQV
MVPLFISVGEMIRVDTRNDSYLGREN

Sequences:

>Translated_186_residues
MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQSGNVVEKTFRAGEQVQQAILEKSNLQHTYVESGDY
VFMDMTSFEETSLTSEQIGKGAKYLKEGMEVNVIFHNGKVLEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQV
MVPLFISVGEMIRVDTRNDSYLGREN
>Mature_186_residues
MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQSGNVVEKTFRAGEQVQQAILEKSNLQHTYVESGDY
VFMDMTSFEETSLTSEQIGKGAKYLKEGMEVNVIFHNGKVLEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQV
MVPLFISVGEMIRVDTRNDSYLGREN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=44.1988950276243, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=30.5263157894737, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20464; Mature: 20464

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQSGNVVEKTFRAGEQV
CCCCCCCCCCCEEEECCHHEEEEHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
QQAILEKSNLQHTYVESGDYVFMDMTSFEETSLTSEQIGKGAKYLKEGMEVNVIFHNGKV
HHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCHHHHCCCHHHHHCCCEEEEEEECCEE
LEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQVMVPLFISVGEMIRVDTRNDS
EEEEECEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHCCCCEEEEECCCCC
YLGREN
CCCCCC
>Mature Secondary Structure
MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQSGNVVEKTFRAGEQV
CCCCCCCCCCCEEEECCHHEEEEHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
QQAILEKSNLQHTYVESGDYVFMDMTSFEETSLTSEQIGKGAKYLKEGMEVNVIFHNGKV
HHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCHHHHCCCHHHHHCCCEEEEEEECCEE
LEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQVMVPLFISVGEMIRVDTRNDS
EEEEECEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHCCCCEEEEECCCCC
YLGREN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA