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The map label for this gene is argS

Identifier: 121999194

GI number: 121999194

Start: 2650699

End: 2652453

Strand: Reverse

Name: argS

Synonym: Hhal_2416

Alternate gene names: 121999194

Gene position: 2652453-2650699 (Counterclockwise)

Preceding gene: 121999195

Following gene: 121999193

Centisome position: 99.03

GC content: 70.66

Gene sequence:

>1755_bases
ATGAAGCGACACGTGGCCAGTCTCCTGGCGCAGGCCCTGAAGGCCATGCGCGAGGCCGGCGAACTGCCGGCGGACCTCGA
GCTGCCCGAGGTACAGGTGGAGCGCGCCCGCGACCGCGCCCACGGTGATTACGCCGCCAACACCGCGATGGTCCTGGCCA
AGCCCGCGCGGCAGAAACCGCGGGACCTGGCCGAGACCATCCGCAGCCGCCTGCCGGCCTCCGAGGCCATCGCCGGCGTG
GAGATCGCCGGCCCCGGCTTCCTGAACTTCACCCTGACCACCGCGGCACGTCAGGAGAGCGTCCGCGTGGCCCTGCGCCA
GGGCGCCGAGTACGGGCGCAGCGACGTGGGGGCGGGGCATCGGGTGCATATCGAGTTCGTCTCCGCCAACCCCACCGGTC
CGCTGCACGTGGGCCACGGGCGGGGGGCCGCCTTCGGCGACGCCCTGGCCAGCGTTCTCGAGGCGGCCGGCTACCACGTC
CACCGCGAGTACTACGTCAACGACGCCGGGCGGCAGATGGACATCCTGGCCGCCTCGCTGTGGCTGCGCTACCTCGAGGC
CGCCGGCGAGCCGGTCTCTTTCCCGAACAAGGGGTACCAGGGGGATTACATCGTCACCCACGCCCGCGAACTGTTCGAGG
CCGACGGCCGCGAACACGTGCGGACCGCCGCCGAGCTCGGTGCCGGGCTGCCGGCGGAGGACGATGACCCGGAGGGGTAT
CTCGACGCCCTGGTGGCCCGTTCCCGCGAGCTCCTCGGCGAGACCGCCTATCGGCGCGTCCTCGACTTTGCCCTGGAGGC
CATCCTCGGGGACATCCGCGCCGATCTGGACGCCTTCGGGGTCCACTACCATCGCTACTTCTCCGAGCGGCAGCTGGTCG
ATCAGGGCCGTATCGAGCATGCCCTGGAGCGGCTCGATCAGGCCGGCTACACCTACCGGGCCGACGGCGCCCTGTGGTTC
CAGGCCTCGGTATTCGGCGACGACAAGGACCGGGTCCTGCGCCGGGACAACGGCCTGACGACGTACTTCGCCGCCGACGT
CGCCTACCACCTGGACAAGATCGAGCGCGGCTTCGACACCCTGGTCAACGTCTGGGGGGCCGACCACCACGGTTACGTGC
CGCGGGTCCAGGCCGCCCTGAAGGCGCTGGGGGTGGATGCGGAGCGCCTGGATGTGCGCCTGGTGCAGTTCGCCATCCTC
TACCGCGGCGGCGAGAAGCTGCCCATGTCCACCCGTTCGGGGGAGTTCGTCACCCTGCGCGAGCTGCGAGACGAGGTGGG
CAAGGACGCGGCGCGGTTCTTCTATGTCATGCGCCGCTCGGAGCAGCACATGGACTTCGACCTGGACCTGGCCAAGTCGG
AGTCGGCGGACAACCCCGTCTACTACTGCCAGTACGCCCACGCGCGCATCTGCAGCGTCTTCCGCCAGCTCGAGGAGCGC
GGCCTGGCCTGCCGCGTCACTCCCGACGAGGCGGCGCTGGAACGCCTCGACGCCGAGCACGAGGCGATCCTCCTCGATCT
CCTCGGCCGGTACCCGGAGGTGATCGAATCGGCGGCGCTGGCGCGGGAGCCGCACCAGGTGGCGCAGTACCTGCGCGAGC
TGGCTGCCGCCTTCCACACCTACTACAACGCGGTGCCGTTCATCATCGACGACGAGGCGCTGCGTGACGCCCGCCTGACG
CTGGTGCAGGCCACCCGGCAGGTCCTGGCCAACGGCCTGGGGCTGCTCGGTGTCGACGCCCCGCAGAGCATGTAG

Upstream 100 bases:

>100_bases
TTATCGCCCCTGGCGGCGAATAATCCGCCCTCCGGCTTGGCATTTTGCCCGGCGCGGCGGGATAATACCGGGCTTTTCCT
GACCCGAGCGGAGACCCTCC

Downstream 100 bases:

>100_bases
CGACGGACCATGGCGCAGAAGAGCACCAAGCCCCGGGGCAACACGCGCAGCAAGGCCCGCACCCCCGCCCGCAGCCGCGG
TGGCGGGGCCCAGGCACGGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKRHVASLLAQALKAMREAGELPADLELPEVQVERARDRAHGDYAANTAMVLAKPARQKPRDLAETIRSRLPASEAIAGV
EIAGPGFLNFTLTTAARQESVRVALRQGAEYGRSDVGAGHRVHIEFVSANPTGPLHVGHGRGAAFGDALASVLEAAGYHV
HREYYVNDAGRQMDILAASLWLRYLEAAGEPVSFPNKGYQGDYIVTHARELFEADGREHVRTAAELGAGLPAEDDDPEGY
LDALVARSRELLGETAYRRVLDFALEAILGDIRADLDAFGVHYHRYFSERQLVDQGRIEHALERLDQAGYTYRADGALWF
QASVFGDDKDRVLRRDNGLTTYFAADVAYHLDKIERGFDTLVNVWGADHHGYVPRVQAALKALGVDAERLDVRLVQFAIL
YRGGEKLPMSTRSGEFVTLRELRDEVGKDAARFFYVMRRSEQHMDFDLDLAKSESADNPVYYCQYAHARICSVFRQLEER
GLACRVTPDEAALERLDAEHEAILLDLLGRYPEVIESAALAREPHQVAQYLRELAAAFHTYYNAVPFIIDDEALRDARLT
LVQATRQVLANGLGLLGVDAPQSM

Sequences:

>Translated_584_residues
MKRHVASLLAQALKAMREAGELPADLELPEVQVERARDRAHGDYAANTAMVLAKPARQKPRDLAETIRSRLPASEAIAGV
EIAGPGFLNFTLTTAARQESVRVALRQGAEYGRSDVGAGHRVHIEFVSANPTGPLHVGHGRGAAFGDALASVLEAAGYHV
HREYYVNDAGRQMDILAASLWLRYLEAAGEPVSFPNKGYQGDYIVTHARELFEADGREHVRTAAELGAGLPAEDDDPEGY
LDALVARSRELLGETAYRRVLDFALEAILGDIRADLDAFGVHYHRYFSERQLVDQGRIEHALERLDQAGYTYRADGALWF
QASVFGDDKDRVLRRDNGLTTYFAADVAYHLDKIERGFDTLVNVWGADHHGYVPRVQAALKALGVDAERLDVRLVQFAIL
YRGGEKLPMSTRSGEFVTLRELRDEVGKDAARFFYVMRRSEQHMDFDLDLAKSESADNPVYYCQYAHARICSVFRQLEER
GLACRVTPDEAALERLDAEHEAILLDLLGRYPEVIESAALAREPHQVAQYLRELAAAFHTYYNAVPFIIDDEALRDARLT
LVQATRQVLANGLGLLGVDAPQSM
>Mature_584_residues
MKRHVASLLAQALKAMREAGELPADLELPEVQVERARDRAHGDYAANTAMVLAKPARQKPRDLAETIRSRLPASEAIAGV
EIAGPGFLNFTLTTAARQESVRVALRQGAEYGRSDVGAGHRVHIEFVSANPTGPLHVGHGRGAAFGDALASVLEAAGYHV
HREYYVNDAGRQMDILAASLWLRYLEAAGEPVSFPNKGYQGDYIVTHARELFEADGREHVRTAAELGAGLPAEDDDPEGY
LDALVARSRELLGETAYRRVLDFALEAILGDIRADLDAFGVHYHRYFSERQLVDQGRIEHALERLDQAGYTYRADGALWF
QASVFGDDKDRVLRRDNGLTTYFAADVAYHLDKIERGFDTLVNVWGADHHGYVPRVQAALKALGVDAERLDVRLVQFAIL
YRGGEKLPMSTRSGEFVTLRELRDEVGKDAARFFYVMRRSEQHMDFDLDLAKSESADNPVYYCQYAHARICSVFRQLEER
GLACRVTPDEAALERLDAEHEAILLDLLGRYPEVIESAALAREPHQVAQYLRELAAAFHTYYNAVPFIIDDEALRDARLT
LVQATRQVLANGLGLLGVDAPQSM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=604, Percent_Identity=24.8344370860927, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1788184, Length=637, Percent_Identity=26.2166405023548, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71985061, Length=590, Percent_Identity=22.7118644067797, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985068, Length=554, Percent_Identity=22.5631768953069, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320548, Length=561, Percent_Identity=25.668449197861, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859963, Length=591, Percent_Identity=23.8578680203046, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_HALHL (A1WZR7)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003981.1
- ProteinModelPortal:   A1WZR7
- STRING:   A1WZR7
- GeneID:   4710936
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2416
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   HHAL349124:HHAL_2416-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64911; Mature: 64911

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHVASLLAQALKAMREAGELPADLELPEVQVERARDRAHGDYAANTAMVLAKPARQKP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHCCCEEEEECCCCCCH
RDLAETIRSRLPASEAIAGVEIAGPGFLNFTLTTAARQESVRVALRQGAEYGRSDVGAGH
HHHHHHHHHHCCHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHHHHCHHCCCHHCCCCC
RVHIEFVSANPTGPLHVGHGRGAAFGDALASVLEAAGYHVHREYYVNDAGRQMDILAASL
EEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEHEEEECCCCCHHHHHHHHH
WLRYLEAAGEPVSFPNKGYQGDYIVTHARELFEADGREHVRTAAELGAGLPAEDDDPEGY
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHH
LDALVARSRELLGETAYRRVLDFALEAILGDIRADLDAFGVHYHRYFSERQLVDQGRIEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALERLDQAGYTYRADGALWFQASVFGDDKDRVLRRDNGLTTYFAADVAYHLDKIERGFDT
HHHHHHHCCCEEEECCEEEEEEEECCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
LVNVWGADHHGYVPRVQAALKALGVDAERLDVRLVQFAILYRGGEKLPMSTRSGEFVTLR
HHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHH
ELRDEVGKDAARFFYVMRRSEQHMDFDLDLAKSESADNPVYYCQYAHARICSVFRQLEER
HHHHHHCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHC
GLACRVTPDEAALERLDAEHEAILLDLLGRYPEVIESAALAREPHQVAQYLRELAAAFHT
CCEEEECCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YYNAVPFIIDDEALRDARLTLVQATRQVLANGLGLLGVDAPQSM
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MKRHVASLLAQALKAMREAGELPADLELPEVQVERARDRAHGDYAANTAMVLAKPARQKP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHCCCEEEEECCCCCCH
RDLAETIRSRLPASEAIAGVEIAGPGFLNFTLTTAARQESVRVALRQGAEYGRSDVGAGH
HHHHHHHHHHCCHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHHHHCHHCCCHHCCCCC
RVHIEFVSANPTGPLHVGHGRGAAFGDALASVLEAAGYHVHREYYVNDAGRQMDILAASL
EEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEHEEEECCCCCHHHHHHHHH
WLRYLEAAGEPVSFPNKGYQGDYIVTHARELFEADGREHVRTAAELGAGLPAEDDDPEGY
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHH
LDALVARSRELLGETAYRRVLDFALEAILGDIRADLDAFGVHYHRYFSERQLVDQGRIEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALERLDQAGYTYRADGALWFQASVFGDDKDRVLRRDNGLTTYFAADVAYHLDKIERGFDT
HHHHHHHCCCEEEECCEEEEEEEECCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
LVNVWGADHHGYVPRVQAALKALGVDAERLDVRLVQFAILYRGGEKLPMSTRSGEFVTLR
HHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHH
ELRDEVGKDAARFFYVMRRSEQHMDFDLDLAKSESADNPVYYCQYAHARICSVFRQLEER
HHHHHHCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHC
GLACRVTPDEAALERLDAEHEAILLDLLGRYPEVIESAALAREPHQVAQYLRELAAAFHT
CCEEEECCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YYNAVPFIIDDEALRDARLTLVQATRQVLANGLGLLGVDAPQSM
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA