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The map label for this gene is rtcB [C]

Identifier: 121999133

GI number: 121999133

Start: 2581473

End: 2582933

Strand: Reverse

Name: rtcB [C]

Synonym: Hhal_2355

Alternate gene names: 121999133

Gene position: 2582933-2581473 (Counterclockwise)

Preceding gene: 121999142

Following gene: 121999130

Centisome position: 96.43

GC content: 70.77

Gene sequence:

>1461_bases
ATGGTCAAGCGTATCGAGGCCGCTGAAGGTCTGGAGTTGGAACGGCTCGACAGTTGCCGCTGGCGGTTGCCGCGGCAGGG
GCGGATGCAGGTAGACGGGTTGATCTTCGCCAACGACGCGTTGATTGAGGACATCCGCGATACCGAGGCCGTGCGCCAGG
TGGCCAATGTGGCCTGCCTCCCCGGGGTGGTCGGGCGGTCCATCGGCATGCCGGATATCCATTGGGGGTTCGGCTTCCCC
ATCGGAGGCGTGGCCGCCTTCGATCCGGACCAGGGGGGCGTGATCTCGCCCGGAGGGGTGGGCTACGACATCAACTGCGG
AGTCCGGCTGCTGCGGACGCCGCTACAGGCCGAGGACCTGGGCGCCCACCTGCCGCGCCTGATGGATCGACTCTTCGAAC
GCATCCCGGCCGGCATGGGCCGTGGGTACGGCGACACCCTGCTGCGCAACCGGGATATGCGCCGGTTGCTGCGCGAGGGG
GCGGCGTGGGCCGTGGAGGTGGGGCTGGGCGAGCCCGAGGATCTGGCCCGGATCGAGGACCGTGGGTGCCTGCCCGGCGC
CGACCCCGAGGCGGTCAGCGATCGGGCCATCCAGCGCGGACGGGATCAGGTCGGTACGGTGGGATCCGGCAACCACTTCA
TCGAGATCGGCTGTGTGGACGATGTCTACGACGAAGCCGCTGCCCGCCGCCTGGGGCTCGAGGCGGGGACGCTGACCGTG
ATGATCCACTCCGGGTCACGCGGGCTCGGTCACCAGGTCTGCGATGACTTTCTGGTGACCATGGAGCGGATCACCGGGCG
CAACGGCATCGAGCTGCCCGACCGTCAGCTGGCCTGCGCGCCGCTGAGCTGCTCCGCCGCCCGGGACTACCTGGGGGCCA
TGCAGGCCGCCGCCAACTTCGCCTACGTCAACCGCCAGGCGATGACCCAGCAGGTGCGCCGGGTCTTCGCCGAGGTGCTG
GGGGAGGAGGCGCACCTGGAGCTGGTCTACGACGTCTCCCACAACATCGCCAAGTTCGAGCGCCATCGGGTCGACGGTGA
GGAGCGCGAGGTCTGCGTCCACCGCAAGGGCGCCACCCGCGCCTTCCCGCCCGGCCACCCGGAACTCCCCGAGGATCTGC
GCGGGCTCGGGCAGCCGGTGCTGCTGCCCGGCGACATGACCCGCTACTCCTACGTCCTGCTCGGCACCCAGGGCGCCTAC
GCCGAGACCTTCGGCTCCTGCGCCCACGGCGCCGGACGCCGTCTCAGCCGGCGCCAGGCCAAACGCGCCGCTGAGGGGCG
GGACTTGGATGCCGAGCTGGCCGAGGCTGGTATCGAGGTGCGCGCCTCGTCCCGGCAGACGGTGGCCGAGGAGCTGGCCG
AGGCGTACAAGGACGTGTCCGATGTGGTGGACGTGGTGGCCCACGCCGGCATTGGCCGCCGGGTGGCCCGCCTGCGTCCG
CTGGGGGTGCTCAAGGGGTGA

Upstream 100 bases:

>100_bases
TCGGGCAGGCTAACCTTGCCGGAGGGGGAGGCCGTCACCGTCCGGGCCGGTGGGCTTGGTACGGTGATCGGGCAACGGGT
GCAACCGCTAGGAGACGGGG

Downstream 100 bases:

>100_bases
GGAGAGGGCGGGGGCTGCGCTAGCGCAGCACCCCGCGCTCCTCCAGGGCGGTGAGGATCTTGCGCACCGAGGTCTCCAGG
TCCTCGGCCACCGTGTCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MVKRIEAAEGLELERLDSCRWRLPRQGRMQVDGLIFANDALIEDIRDTEAVRQVANVACLPGVVGRSIGMPDIHWGFGFP
IGGVAAFDPDQGGVISPGGVGYDINCGVRLLRTPLQAEDLGAHLPRLMDRLFERIPAGMGRGYGDTLLRNRDMRRLLREG
AAWAVEVGLGEPEDLARIEDRGCLPGADPEAVSDRAIQRGRDQVGTVGSGNHFIEIGCVDDVYDEAAARRLGLEAGTLTV
MIHSGSRGLGHQVCDDFLVTMERITGRNGIELPDRQLACAPLSCSAARDYLGAMQAAANFAYVNRQAMTQQVRRVFAEVL
GEEAHLELVYDVSHNIAKFERHRVDGEEREVCVHRKGATRAFPPGHPELPEDLRGLGQPVLLPGDMTRYSYVLLGTQGAY
AETFGSCAHGAGRRLSRRQAKRAAEGRDLDAELAEAGIEVRASSRQTVAEELAEAYKDVSDVVDVVAHAGIGRRVARLRP
LGVLKG

Sequences:

>Translated_486_residues
MVKRIEAAEGLELERLDSCRWRLPRQGRMQVDGLIFANDALIEDIRDTEAVRQVANVACLPGVVGRSIGMPDIHWGFGFP
IGGVAAFDPDQGGVISPGGVGYDINCGVRLLRTPLQAEDLGAHLPRLMDRLFERIPAGMGRGYGDTLLRNRDMRRLLREG
AAWAVEVGLGEPEDLARIEDRGCLPGADPEAVSDRAIQRGRDQVGTVGSGNHFIEIGCVDDVYDEAAARRLGLEAGTLTV
MIHSGSRGLGHQVCDDFLVTMERITGRNGIELPDRQLACAPLSCSAARDYLGAMQAAANFAYVNRQAMTQQVRRVFAEVL
GEEAHLELVYDVSHNIAKFERHRVDGEEREVCVHRKGATRAFPPGHPELPEDLRGLGQPVLLPGDMTRYSYVLLGTQGAY
AETFGSCAHGAGRRLSRRQAKRAAEGRDLDAELAEAGIEVRASSRQTVAEELAEAYKDVSDVVDVVAHAGIGRRVARLRP
LGVLKG
>Mature_486_residues
MVKRIEAAEGLELERLDSCRWRLPRQGRMQVDGLIFANDALIEDIRDTEAVRQVANVACLPGVVGRSIGMPDIHWGFGFP
IGGVAAFDPDQGGVISPGGVGYDINCGVRLLRTPLQAEDLGAHLPRLMDRLFERIPAGMGRGYGDTLLRNRDMRRLLREG
AAWAVEVGLGEPEDLARIEDRGCLPGADPEAVSDRAIQRGRDQVGTVGSGNHFIEIGCVDDVYDEAAARRLGLEAGTLTV
MIHSGSRGLGHQVCDDFLVTMERITGRNGIELPDRQLACAPLSCSAARDYLGAMQAAANFAYVNRQAMTQQVRRVFAEVL
GEEAHLELVYDVSHNIAKFERHRVDGEEREVCVHRKGATRAFPPGHPELPEDLRGLGQPVLLPGDMTRYSYVLLGTQGAY
AETFGSCAHGAGRRLSRRQAKRAAEGRDLDAELAEAGIEVRASSRQTVAEELAEAYKDVSDVVDVVAHAGIGRRVARLRP
LGVLKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=495, Percent_Identity=46.2626262626263, Blast_Score=432, Evalue=1e-121,
Organism=Escherichia coli, GI2367224, Length=449, Percent_Identity=30.5122494432071, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17506665, Length=495, Percent_Identity=45.0505050505051, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24585217, Length=507, Percent_Identity=47.1400394477318, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 52850; Mature: 52850

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRIEAAEGLELERLDSCRWRLPRQGRMQVDGLIFANDALIEDIRDTEAVRQVANVACL
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECCEEEECHHHHHHHHHHHHHHHHHHHHHH
PGVVGRSIGMPDIHWGFGFPIGGVAAFDPDQGGVISPGGVGYDINCGVRLLRTPLQAEDL
HHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCEECCCCHHHHHCCCCHHHH
GAHLPRLMDRLFERIPAGMGRGYGDTLLRNRDMRRLLREGAAWAVEVGLGEPEDLARIED
HHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
RGCLPGADPEAVSDRAIQRGRDQVGTVGSGNHFIEIGCVDDVYDEAAARRLGLEAGTLTV
CCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEE
MIHSGSRGLGHQVCDDFLVTMERITGRNGIELPDRQLACAPLSCSAARDYLGAMQAAANF
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
AYVNRQAMTQQVRRVFAEVLGEEAHLELVYDVSHNIAKFERHRVDGEEREVCVHRKGATR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHEEEECCCCCC
AFPPGHPELPEDLRGLGQPVLLPGDMTRYSYVLLGTQGAYAETFGSCAHGAGRRLSRRQA
CCCCCCCCCCHHHHHCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
KRAAEGRDLDAELAEAGIEVRASSRQTVAEELAEAYKDVSDVVDVVAHAGIGRRVARLRP
HHHHCCCCCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
LGVLKG
CCCCCC
>Mature Secondary Structure
MVKRIEAAEGLELERLDSCRWRLPRQGRMQVDGLIFANDALIEDIRDTEAVRQVANVACL
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECCEEEECHHHHHHHHHHHHHHHHHHHHHH
PGVVGRSIGMPDIHWGFGFPIGGVAAFDPDQGGVISPGGVGYDINCGVRLLRTPLQAEDL
HHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEECCCCCCEECCCCHHHHHCCCCHHHH
GAHLPRLMDRLFERIPAGMGRGYGDTLLRNRDMRRLLREGAAWAVEVGLGEPEDLARIED
HHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
RGCLPGADPEAVSDRAIQRGRDQVGTVGSGNHFIEIGCVDDVYDEAAARRLGLEAGTLTV
CCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEE
MIHSGSRGLGHQVCDDFLVTMERITGRNGIELPDRQLACAPLSCSAARDYLGAMQAAANF
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
AYVNRQAMTQQVRRVFAEVLGEEAHLELVYDVSHNIAKFERHRVDGEEREVCVHRKGATR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHEEEECCCCCC
AFPPGHPELPEDLRGLGQPVLLPGDMTRYSYVLLGTQGAYAETFGSCAHGAGRRLSRRQA
CCCCCCCCCCHHHHHCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
KRAAEGRDLDAELAEAGIEVRASSRQTVAEELAEAYKDVSDVVDVVAHAGIGRRVARLRP
HHHHCCCCCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
LGVLKG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]