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The map label for this gene is dsbD [H]

Identifier: 121999116

GI number: 121999116

Start: 2563347

End: 2565176

Strand: Reverse

Name: dsbD [H]

Synonym: Hhal_2338

Alternate gene names: 121999116

Gene position: 2565176-2563347 (Counterclockwise)

Preceding gene: 121999117

Following gene: 121999115

Centisome position: 95.77

GC content: 69.73

Gene sequence:

>1830_bases
ATGACGGGCAGGATGCGATTCGACCGAGGTGGCCTGGTCGCCGCGCTGTGGCTGGCGTTGGGTCTGCTGGTGGCGGCCAC
CCCGGCACAGGGAATGGTGGATCAACAGGAGATCTTCCCGTTCACCGTCGAGCAGGTGGGCGAGGATCGCCTGGTCGCTC
GCTGGGATGTGGCCGAGGACCACTACCTCTATCGCCACGCCTTCGACTTCGAGCTGCGCGACGGCGACAACGAGATCATC
GAGGTCTCCTACCCCAGTGGCGAGGCCTTCTCCGATGAGTTCTTCGGGGATGTGGTCATCTACCGGGGTACGCTGCAGGT
GCACCTGCAGACCGCCGAACCGGTCGGCGAGGGGGCGCAGCTCTACGCCGAGTTCCAGGGCTGCAACGAGCCCGAATCCC
TCTGCTATCCGCCGAGCAGTCTGGAAGCCGAGATCGCCTCCGGCGCGGTACAGTACAGCGATGGCTCCGGCGGTGCCGGT
GCCGCCGGGGGCGGCGGCCAGGGCCCCATGGGCGAGCTGGAGGCGCTGCTCGGTGGGGGGAATCTGTGGGCCATCCTCGG
CGGTTTCTTTGCCGCCGGGCTGTTGCTGGCCTTCACCGCCTGCATCTACCCGATGATCCCCATCCTCTCGGGGCTGATCG
TCGGTAGCCAGCCGGGCGGCGGGCGGCCGGGTACCGGTCGAGCGCTCTGGCTGTCCTTCGTCTATGTCCAGGGCATGGCG
ATCACCTACGCCCTGGCCGGTGCATTGGCCGGACTCTCCGGGCGGGCCATCCAGGCCGATCTGCAGGGGCCGGTGGTTAC
CGTGGCCTTCAGTGCCCTGTTCGTCGCCCTGGCGCTGGCGATGTTCGGCCTCTACAACCTGCAGATGCCGGCGTCGGTCC
AGGGGCGGCTGCAGGCCGCCTCCAGCCGTCTGCCCGGCGGGCAGGTGGCGGGCGTGGCAGCCATGGGTGTGCTCTCCACG
CTGATCGTCGGTGCCTGCTCGGGGCCGGCGCTGGTGGCCGCCCTGGCATTCATCGGCAACACCGGTGAGGTGGTGCTGGG
CGCCGGCGCGCTCTACATCATGGCCCTGGGTATGGGGGCGCCGTTGCTGGCGGTCGGCACGGCCGCCGGGCGCTGGATGC
CGCGCTCGGGTCCGTGGATGGAGTCGGTCAAGCAGGTCTTCGGCTTCATCTTCCTCGGCGTGGCGTGGTGGATGTCGTCC
CGGCTGATGCCGGATGGGCTGGTGCTCGCTGGTTGGGCGGTGTTGCTGCTGGCGGCTGCGGTGTGGCTGGCCTGGCGGCT
GCTGCGCAGTCGCGGCACCGGTGGTTCGGTGCCGGCCCGGGGCGCCGGGGCCACGCTGGCGGCCGTGCTGGCGGTAGCCG
GTGCTGCCCAGGTCCTCGGGGCGGTCACCGGTGCCGGTGACCCGCTGCGCCCCTGGGTGGGGATCACCGGCGACCCATAC
GCCCAGGCCCGCGCCCAGGTGCTCGAGGAGTGGCGGCACGTCGAGACCCTCGATGAGCTTGAGGAGCTGCTTGACGAGGC
CCGCGAGGCGGGGCGCCCGGTGGTGATCGACTTCTCGGCCGAGTGGTGCGTCTACTGTGTCCAGCTTGAGGAGCGTACGC
TTCCGGATGACCGGGTCCAGGCGGCCCTTGAAGGCGCCGAGAAGGTACGCATCGACGTCACCGACATGACCGATGCTGAT
CGGGAACTGATGGAGGCCTACGGCGTCTATCTGCCTCCCGCGATCCTGTTCTACAACGGCGAGGGCGAGGAGCAATCGGA
GTACCGGGTGGCCGGCTTCAAGGACGCCGAGGCGTTTGCCGAGCGCACGCGCGAGGCCTTCGGTGGGTGA

Upstream 100 bases:

>100_bases
CCTATGAACTTCCGGAGGTGATCGCGGTCGGCATCGAAAAGGGCCTGTCAGGGTTCCTGGACTGGATACGTGAAGAAACC
CGGTAGGAGGGCATGACTCG

Downstream 100 bases:

>100_bases
CCGGGGGGTCTGGGACGTTGCGGTCCACGCCGGCCGGGGTAGCCGGCCGGCGTGGACGGTGGGCGTGGACAATCGGTCGC
AGGCATCCCCGGCGAAACGG

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MTGRMRFDRGGLVAALWLALGLLVAATPAQGMVDQQEIFPFTVEQVGEDRLVARWDVAEDHYLYRHAFDFELRDGDNEII
EVSYPSGEAFSDEFFGDVVIYRGTLQVHLQTAEPVGEGAQLYAEFQGCNEPESLCYPPSSLEAEIASGAVQYSDGSGGAG
AAGGGGQGPMGELEALLGGGNLWAILGGFFAAGLLLAFTACIYPMIPILSGLIVGSQPGGGRPGTGRALWLSFVYVQGMA
ITYALAGALAGLSGRAIQADLQGPVVTVAFSALFVALALAMFGLYNLQMPASVQGRLQAASSRLPGGQVAGVAAMGVLST
LIVGACSGPALVAALAFIGNTGEVVLGAGALYIMALGMGAPLLAVGTAAGRWMPRSGPWMESVKQVFGFIFLGVAWWMSS
RLMPDGLVLAGWAVLLLAAAVWLAWRLLRSRGTGGSVPARGAGATLAAVLAVAGAAQVLGAVTGAGDPLRPWVGITGDPY
AQARAQVLEEWRHVETLDELEELLDEAREAGRPVVIDFSAEWCVYCVQLEERTLPDDRVQAALEGAEKVRIDVTDMTDAD
RELMEAYGVYLPPAILFYNGEGEEQSEYRVAGFKDAEAFAERTREAFGG

Sequences:

>Translated_609_residues
MTGRMRFDRGGLVAALWLALGLLVAATPAQGMVDQQEIFPFTVEQVGEDRLVARWDVAEDHYLYRHAFDFELRDGDNEII
EVSYPSGEAFSDEFFGDVVIYRGTLQVHLQTAEPVGEGAQLYAEFQGCNEPESLCYPPSSLEAEIASGAVQYSDGSGGAG
AAGGGGQGPMGELEALLGGGNLWAILGGFFAAGLLLAFTACIYPMIPILSGLIVGSQPGGGRPGTGRALWLSFVYVQGMA
ITYALAGALAGLSGRAIQADLQGPVVTVAFSALFVALALAMFGLYNLQMPASVQGRLQAASSRLPGGQVAGVAAMGVLST
LIVGACSGPALVAALAFIGNTGEVVLGAGALYIMALGMGAPLLAVGTAAGRWMPRSGPWMESVKQVFGFIFLGVAWWMSS
RLMPDGLVLAGWAVLLLAAAVWLAWRLLRSRGTGGSVPARGAGATLAAVLAVAGAAQVLGAVTGAGDPLRPWVGITGDPY
AQARAQVLEEWRHVETLDELEELLDEAREAGRPVVIDFSAEWCVYCVQLEERTLPDDRVQAALEGAEKVRIDVTDMTDAD
RELMEAYGVYLPPAILFYNGEGEEQSEYRVAGFKDAEAFAERTREAFGG
>Mature_608_residues
TGRMRFDRGGLVAALWLALGLLVAATPAQGMVDQQEIFPFTVEQVGEDRLVARWDVAEDHYLYRHAFDFELRDGDNEIIE
VSYPSGEAFSDEFFGDVVIYRGTLQVHLQTAEPVGEGAQLYAEFQGCNEPESLCYPPSSLEAEIASGAVQYSDGSGGAGA
AGGGGQGPMGELEALLGGGNLWAILGGFFAAGLLLAFTACIYPMIPILSGLIVGSQPGGGRPGTGRALWLSFVYVQGMAI
TYALAGALAGLSGRAIQADLQGPVVTVAFSALFVALALAMFGLYNLQMPASVQGRLQAASSRLPGGQVAGVAAMGVLSTL
IVGACSGPALVAALAFIGNTGEVVLGAGALYIMALGMGAPLLAVGTAAGRWMPRSGPWMESVKQVFGFIFLGVAWWMSSR
LMPDGLVLAGWAVLLLAAAVWLAWRLLRSRGTGGSVPARGAGATLAAVLAVAGAAQVLGAVTGAGDPLRPWVGITGDPYA
QARAQVLEEWRHVETLDELEELLDEAREAGRPVVIDFSAEWCVYCVQLEERTLPDDRVQAALEGAEKVRIDVTDMTDADR
ELMEAYGVYLPPAILFYNGEGEEQSEYRVAGFKDAEAFAERTREAFGG

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=575, Percent_Identity=34.4347826086956, Blast_Score=304, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64003; Mature: 63872

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRMRFDRGGLVAALWLALGLLVAATPAQGMVDQQEIFPFTVEQVGEDRLVARWDVAED
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCEEEEECCCCC
HYLYRHAFDFELRDGDNEIIEVSYPSGEAFSDEFFGDVVIYRGTLQVHLQTAEPVGEGAQ
CEEEEEEEEEEEECCCCCEEEEECCCCCCCCHHHCCCEEEEEEEEEEEEEECCCCCCCHH
LYAEFQGCNEPESLCYPPSSLEAEIASGAVQYSDGSGGAGAAGGGGQGPMGELEALLGGG
HHHHHCCCCCCHHCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCC
NLWAILGGFFAAGLLLAFTACIYPMIPILSGLIVGSQPGGGRPGTGRALWLSFVYVQGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ITYALAGALAGLSGRAIQADLQGPVVTVAFSALFVALALAMFGLYNLQMPASVQGRLQAA
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SSRLPGGQVAGVAAMGVLSTLIVGACSGPALVAALAFIGNTGEVVLGAGALYIMALGMGA
HCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCC
PLLAVGTAAGRWMPRSGPWMESVKQVFGFIFLGVAWWMSSRLMPDGLVLAGWAVLLLAAA
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VWLAWRLLRSRGTGGSVPARGAGATLAAVLAVAGAAQVLGAVTGAGDPLRPWVGITGDPY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AQARAQVLEEWRHVETLDELEELLDEAREAGRPVVIDFSAEWCVYCVQLEERTLPDDRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEHHCCCCCHHHHH
AALEGAEKVRIDVTDMTDADRELMEAYGVYLPPAILFYNGEGEEQSEYRVAGFKDAEAFA
HHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEECCCCHHHHHH
ERTREAFGG
HHHHHHHCC
>Mature Secondary Structure 
TGRMRFDRGGLVAALWLALGLLVAATPAQGMVDQQEIFPFTVEQVGEDRLVARWDVAED
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCEEEEECCCCC
HYLYRHAFDFELRDGDNEIIEVSYPSGEAFSDEFFGDVVIYRGTLQVHLQTAEPVGEGAQ
CEEEEEEEEEEEECCCCCEEEEECCCCCCCCHHHCCCEEEEEEEEEEEEEECCCCCCCHH
LYAEFQGCNEPESLCYPPSSLEAEIASGAVQYSDGSGGAGAAGGGGQGPMGELEALLGGG
HHHHHCCCCCCHHCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCC
NLWAILGGFFAAGLLLAFTACIYPMIPILSGLIVGSQPGGGRPGTGRALWLSFVYVQGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ITYALAGALAGLSGRAIQADLQGPVVTVAFSALFVALALAMFGLYNLQMPASVQGRLQAA
HHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SSRLPGGQVAGVAAMGVLSTLIVGACSGPALVAALAFIGNTGEVVLGAGALYIMALGMGA
HCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCC
PLLAVGTAAGRWMPRSGPWMESVKQVFGFIFLGVAWWMSSRLMPDGLVLAGWAVLLLAAA
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VWLAWRLLRSRGTGGSVPARGAGATLAAVLAVAGAAQVLGAVTGAGDPLRPWVGITGDPY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AQARAQVLEEWRHVETLDELEELLDEAREAGRPVVIDFSAEWCVYCVQLEERTLPDDRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEHHCCCCCHHHHH
AALEGAEKVRIDVTDMTDADRELMEAYGVYLPPAILFYNGEGEEQSEYRVAGFKDAEAFA
HHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEECCCCHHHHHH
ERTREAFGG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]