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The map label for this gene is glcB [H]

Identifier: 121999026

GI number: 121999026

Start: 2466855

End: 2469038

Strand: Reverse

Name: glcB [H]

Synonym: Hhal_2247

Alternate gene names: 121999026

Gene position: 2469038-2466855 (Counterclockwise)

Preceding gene: 121999027

Following gene: 121999025

Centisome position: 92.18

GC content: 66.94

Gene sequence:

>2184_bases
ATGAGCGAACGGGTTCAAGTCGGTGGCCTGCAGGTGGCGCGTGAACTCCACGACCTGGTGGCCAACGAGATCGTGCCGGG
GACCGGCATCGACGCCGACACCGTGTGGGACGAGCTCGGCGGCATCGTCCGCGATCTGGCTCCGCGCAACCGCGAGTTGC
TGGAACAGCGCGAGAACTTGCAGCGGCAGATCGACGACTGGCATCGGAACCATCGTGGCCAGTTCTCGGTATCCGATCAC
AAGGCGTTCCTTGAGCAGATCGGCTACCTGGAACCCGAAGTGGACGCGTTCGAGATCACCACCACCGGGGTCGACCCGGA
GATCGCCACCGTGGCCGGGCCGCAGCTGGTGGTGCCGGTCGATAACGCGCGATTCGCGCTCAACGCGGCCAACGCGCGCT
GGGGCAGCCTGTTCGATGCCCTCTACGGCACCGACATGATCCCCGAGAGCGACGGGCTAGCCAAGGGCAAGACGTACAAT
CCCGCTCGCGGTAAAAAGGTCATGGAGTTGGCCGCCGAGACCCTGGACGAGGTGGCCCCGCTGGCCCATGGGCTCCACGC
CGAGGTTACCGCCTACCGGCTGAGCGACGGCAACCCGCGCCAGCTGGTCATCACCCTGGCCGACGGCAGTGAGACCGAAC
TGGCCGATCCGACCCGCTTCGTCGGCTTCACCGGCGAGCCGGATCGCCCCGCCACCCTCCTGCTGCGCCACAACGGCCTC
CACGCCGAGATCGTCATCGACCCGAACGACCCGATCGGTCAGGATCACCCGGCCGGCGTCAAGGACGTGGTCATGGAGTC
GGCGCTGACCGCCATCCAGGACTGCGAGGACTCCGTGGCCGCGGTGGACGCCGAGGACAAGGTGCGCGTCTACCGCAACT
GGTTGGGCCTGATGAAAGGCGACCTAGAGACGTCGGTGAGCAAGGGCGGCGAGACCTTTACGCGGCGGCTCAACCCGGAT
CGCACCTACACGGCCCCGGACGGCGGCTCGCTGACCCTGCCGGGCCGCTCGCTCATGCTGGTGCGCAATGTCGGTCACCT
GATGACCACACCGGCGGTCCTCGACGGCGACGGCAACGAGATCCCCGAGGGCATGCTCGACGCCATGATGACCGTCCTCT
GCGCGGTCCACGACCTCAAGGGGCTCGGACAGGTATGCAACTCGAAGACCGGCAGCGTCTACATCGTCAAGCCGAAGATG
CACGGTCCCGAGGAGGTGGCGCTGACCGTGAACCTGTTCGAGCGCGTCGAGGACGCCCTGGGTCTGGCGCGTGCCACCCT
CAAGGTGGGCATCATGGATGAGGAGCGGCGCACTACGGTCAACCTGCGTGCCTGCATCCAGCAGGCCCGGGATCGGGTGA
TCTTCATCAACACCGGCTTCCTCGACCGCACTGGCGACGAGATCCACACCGCCATGGAGGCCGGCGCGGTGATCCGCAAG
GCGGACATGAAGGGGGCCGCCTTCATGACCACCTACGAGGACTGGAACGTCGATGTCGGCCTGGCTTCCGGCTTCAAGGG
CAAGGCCCAGATCGGCAAGGGCATGTGGCCGAAGCCGGACAAGATGCGCGAGATGTTCGACACCAAGGCTGGCCACCCCA
AGGCAGGCGCGAACTGTGCCTGGGTGCCGTCGCCGACGGCGGCGACCCTGCACGCTGTGCACTACCACCAGGTGGACGTG
GCTGGCGTCCAGGCCGAGATCGCCCGGGAGGGGTGGCGTTCCGACCTGAGCCGGATCCTCACCGTGCCGCTGGCGCCGAG
CACCGACTGGAGCGCCGAGGAGATCCAGCAGGAGGTGGACAACAACTGCCAGGGCATCCTCGGCTATGTGGTGCGCTGGA
TCGACCAGGGCATTGGCTGCTCCAAGGTCCCGGACGTCAATAACGTGGGGCTGATGGAGGATCGCGCCACGCTGCGCATC
TCCAGCCAGCACGTGGCCAACTGGCTCTACCACGGCGTGGTGACCGAGGAGCAGGTCATGGACAGCCTCAAGCGCATGGC
CCAGGTGGTCGACGAGCAGAACGCCGGCGACCCGAACTACCGCCCCATGGCCGAAGACTTCGACGGCAGCGTCGCCTTCC
AGGCGGCCTGTGATCTGGTCTTCAAGGGGCGGGAGCAGCCCTCCGGTTACACCGAGCCGGTGCTCCATCGCCGTCGGCAG
GAGGCGAAGGCGAAGTACGCCTGA

Upstream 100 bases:

>100_bases
AACGCTGAGCGGGGCGGCGTACGGCGGATGATCAGGCTGACTTGGATGCGTTACTATCGCGGCTTATCCGCGGATCGCGA
AGCTGAATAGGGAGACTTCC

Downstream 100 bases:

>100_bases
TTCCGCCGCCTGAACGACATCCCGTGAACCGTACCGGCGTCGGCAGCCCCCGGGCTGTCGGCGCCGTCTTGTCTCTGGAA
GCCTGACCGTGCGCGAACCG

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MSERVQVGGLQVARELHDLVANEIVPGTGIDADTVWDELGGIVRDLAPRNRELLEQRENLQRQIDDWHRNHRGQFSVSDH
KAFLEQIGYLEPEVDAFEITTTGVDPEIATVAGPQLVVPVDNARFALNAANARWGSLFDALYGTDMIPESDGLAKGKTYN
PARGKKVMELAAETLDEVAPLAHGLHAEVTAYRLSDGNPRQLVITLADGSETELADPTRFVGFTGEPDRPATLLLRHNGL
HAEIVIDPNDPIGQDHPAGVKDVVMESALTAIQDCEDSVAAVDAEDKVRVYRNWLGLMKGDLETSVSKGGETFTRRLNPD
RTYTAPDGGSLTLPGRSLMLVRNVGHLMTTPAVLDGDGNEIPEGMLDAMMTVLCAVHDLKGLGQVCNSKTGSVYIVKPKM
HGPEEVALTVNLFERVEDALGLARATLKVGIMDEERRTTVNLRACIQQARDRVIFINTGFLDRTGDEIHTAMEAGAVIRK
ADMKGAAFMTTYEDWNVDVGLASGFKGKAQIGKGMWPKPDKMREMFDTKAGHPKAGANCAWVPSPTAATLHAVHYHQVDV
AGVQAEIAREGWRSDLSRILTVPLAPSTDWSAEEIQQEVDNNCQGILGYVVRWIDQGIGCSKVPDVNNVGLMEDRATLRI
SSQHVANWLYHGVVTEEQVMDSLKRMAQVVDEQNAGDPNYRPMAEDFDGSVAFQAACDLVFKGREQPSGYTEPVLHRRRQ
EAKAKYA

Sequences:

>Translated_727_residues
MSERVQVGGLQVARELHDLVANEIVPGTGIDADTVWDELGGIVRDLAPRNRELLEQRENLQRQIDDWHRNHRGQFSVSDH
KAFLEQIGYLEPEVDAFEITTTGVDPEIATVAGPQLVVPVDNARFALNAANARWGSLFDALYGTDMIPESDGLAKGKTYN
PARGKKVMELAAETLDEVAPLAHGLHAEVTAYRLSDGNPRQLVITLADGSETELADPTRFVGFTGEPDRPATLLLRHNGL
HAEIVIDPNDPIGQDHPAGVKDVVMESALTAIQDCEDSVAAVDAEDKVRVYRNWLGLMKGDLETSVSKGGETFTRRLNPD
RTYTAPDGGSLTLPGRSLMLVRNVGHLMTTPAVLDGDGNEIPEGMLDAMMTVLCAVHDLKGLGQVCNSKTGSVYIVKPKM
HGPEEVALTVNLFERVEDALGLARATLKVGIMDEERRTTVNLRACIQQARDRVIFINTGFLDRTGDEIHTAMEAGAVIRK
ADMKGAAFMTTYEDWNVDVGLASGFKGKAQIGKGMWPKPDKMREMFDTKAGHPKAGANCAWVPSPTAATLHAVHYHQVDV
AGVQAEIAREGWRSDLSRILTVPLAPSTDWSAEEIQQEVDNNCQGILGYVVRWIDQGIGCSKVPDVNNVGLMEDRATLRI
SSQHVANWLYHGVVTEEQVMDSLKRMAQVVDEQNAGDPNYRPMAEDFDGSVAFQAACDLVFKGREQPSGYTEPVLHRRRQ
EAKAKYA
>Mature_726_residues
SERVQVGGLQVARELHDLVANEIVPGTGIDADTVWDELGGIVRDLAPRNRELLEQRENLQRQIDDWHRNHRGQFSVSDHK
AFLEQIGYLEPEVDAFEITTTGVDPEIATVAGPQLVVPVDNARFALNAANARWGSLFDALYGTDMIPESDGLAKGKTYNP
ARGKKVMELAAETLDEVAPLAHGLHAEVTAYRLSDGNPRQLVITLADGSETELADPTRFVGFTGEPDRPATLLLRHNGLH
AEIVIDPNDPIGQDHPAGVKDVVMESALTAIQDCEDSVAAVDAEDKVRVYRNWLGLMKGDLETSVSKGGETFTRRLNPDR
TYTAPDGGSLTLPGRSLMLVRNVGHLMTTPAVLDGDGNEIPEGMLDAMMTVLCAVHDLKGLGQVCNSKTGSVYIVKPKMH
GPEEVALTVNLFERVEDALGLARATLKVGIMDEERRTTVNLRACIQQARDRVIFINTGFLDRTGDEIHTAMEAGAVIRKA
DMKGAAFMTTYEDWNVDVGLASGFKGKAQIGKGMWPKPDKMREMFDTKAGHPKAGANCAWVPSPTAATLHAVHYHQVDVA
GVQAEIAREGWRSDLSRILTVPLAPSTDWSAEEIQQEVDNNCQGILGYVVRWIDQGIGCSKVPDVNNVGLMEDRATLRIS
SQHVANWLYHGVVTEEQVMDSLKRMAQVVDEQNAGDPNYRPMAEDFDGSVAFQAACDLVFKGREQPSGYTEPVLHRRRQE
AKAKYA

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=731, Percent_Identity=55.6771545827633, Blast_Score=839, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79617; Mature: 79486

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVQVGGLQVARELHDLVANEIVPGTGIDADTVWDELGGIVRDLAPRNRELLEQRENL
CCCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QRQIDDWHRNHRGQFSVSDHKAFLEQIGYLEPEVDAFEITTTGVDPEIATVAGPQLVVPV
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCCEEEEEE
DNARFALNAANARWGSLFDALYGTDMIPESDGLAKGKTYNPARGKKVMELAAETLDEVAP
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAHGLHAEVTAYRLSDGNPRQLVITLADGSETELADPTRFVGFTGEPDRPATLLLRHNGL
HHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEEEEECCC
HAEIVIDPNDPIGQDHPAGVKDVVMESALTAIQDCEDSVAAVDAEDKVRVYRNWLGLMKG
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHC
DLETSVSKGGETFTRRLNPDRTYTAPDGGSLTLPGRSLMLVRNVGHLMTTPAVLDGDGNE
CHHHHHHCCCHHHHHCCCCCCCEECCCCCEEECCCCCEEEEHHCCHHHCCCEEECCCCCC
IPEGMLDAMMTVLCAVHDLKGLGQVCNSKTGSVYIVKPKMHGPEEVALTVNLFERVEDAL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHH
GLARATLKVGIMDEERRTTVNLRACIQQARDRVIFINTGFLDRTGDEIHTAMEAGAVIRK
HHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
ADMKGAAFMTTYEDWNVDVGLASGFKGKAQIGKGMWPKPDKMREMFDTKAGHPKAGANCA
CCCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEE
WVPSPTAATLHAVHYHQVDVAGVQAEIAREGWRSDLSRILTVPLAPSTDWSAEEIQQEVD
ECCCCCHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHC
NNCQGILGYVVRWIDQGIGCSKVPDVNNVGLMEDRATLRISSQHVANWLYHGVVTEEQVM
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHH
DSLKRMAQVVDEQNAGDPNYRPMAEDFDGSVAFQAACDLVFKGREQPSGYTEPVLHRRRQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EAKAKYA
HHHCCCC
>Mature Secondary Structure 
SERVQVGGLQVARELHDLVANEIVPGTGIDADTVWDELGGIVRDLAPRNRELLEQRENL
CCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QRQIDDWHRNHRGQFSVSDHKAFLEQIGYLEPEVDAFEITTTGVDPEIATVAGPQLVVPV
HHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCCEEEEEE
DNARFALNAANARWGSLFDALYGTDMIPESDGLAKGKTYNPARGKKVMELAAETLDEVAP
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAHGLHAEVTAYRLSDGNPRQLVITLADGSETELADPTRFVGFTGEPDRPATLLLRHNGL
HHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEEEEECCC
HAEIVIDPNDPIGQDHPAGVKDVVMESALTAIQDCEDSVAAVDAEDKVRVYRNWLGLMKG
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHC
DLETSVSKGGETFTRRLNPDRTYTAPDGGSLTLPGRSLMLVRNVGHLMTTPAVLDGDGNE
CHHHHHHCCCHHHHHCCCCCCCEECCCCCEEECCCCCEEEEHHCCHHHCCCEEECCCCCC
IPEGMLDAMMTVLCAVHDLKGLGQVCNSKTGSVYIVKPKMHGPEEVALTVNLFERVEDAL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHH
GLARATLKVGIMDEERRTTVNLRACIQQARDRVIFINTGFLDRTGDEIHTAMEAGAVIRK
HHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
ADMKGAAFMTTYEDWNVDVGLASGFKGKAQIGKGMWPKPDKMREMFDTKAGHPKAGANCA
CCCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEE
WVPSPTAATLHAVHYHQVDVAGVQAEIAREGWRSDLSRILTVPLAPSTDWSAEEIQQEVD
ECCCCCHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHC
NNCQGILGYVVRWIDQGIGCSKVPDVNNVGLMEDRATLRISSQHVANWLYHGVVTEEQVM
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHH
DSLKRMAQVVDEQNAGDPNYRPMAEDFDGSVAFQAACDLVFKGREQPSGYTEPVLHRRRQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EAKAKYA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA