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The map label for this gene is hisC2 [H]

Identifier: 121998890

GI number: 121998890

Start: 2316090

End: 2317187

Strand: Reverse

Name: hisC2 [H]

Synonym: Hhal_2111

Alternate gene names: 121998890

Gene position: 2317187-2316090 (Counterclockwise)

Preceding gene: 121998891

Following gene: 121998888

Centisome position: 86.51

GC content: 70.13

Gene sequence:

>1098_bases
GTGACTGAGGTCGAGGCGCGGGTCGCCCGCTGGGTGCGGCCACAGGTGCAGGCCCTGGAGGCCTATCAGGTGGCCGAGCC
GGGCAAGGCCATCAAGCTCGATGCCATGGAGAGCCCATGGGCCTGGCCCGGGGCCCTGGAAGAGGCCTGGCTGGAGCGCA
TGCGTTCGGTGTCCGTGAACCGCTATCCGGACCCGGCGGCCCGGCGGCTCAAGCCCCTGCTGCGCGAGGGGTTGGGGGTC
CCCGAGGGGGCAGAGCTGTTGCTCGGCAACGGCTCCGATGAGCTCATCCAGCTCATCGATCTGGCCGTGGCTGGCAGTGG
GCGCACGGTGATGGCCCCGGGGCCGAGTTTTGCCATGTACCGGATCATCGCCGAGTATACCGGCGCCGAATACGTCGAGG
TGCCGCTCGATGCGGAGTTCGGGCTGGATCTCGCCGCCACCCGGGAGGCGGTGTCGGCGTACAACCCGGCGGTCACCTAC
CTGGCGCACCCGAACAACCCCACCGGCAATGGCCTCGATCTGGACGCCGTGGCGGAGCTGGTGGCGCAGAGCGACGGCCT
GGTGGTAGTCGATGAGGCCTACGCCCCCTACGCCGACAGCAGCTTCCTGCCGCGGGTGCTGGAGTTCCCCAACTGCCTGG
TGCTGCGCACGCTCTCTAAGGTCGGTCTGGCGGGCCTGCGGGTCGGGGTGCTGATCGGCCATCCGGCCTGGATCGACCAG
CTGGAGAAGTGTCGCCTGCCCTACAACCTGGGCAGCCTGGCCCAGGCCAGTGCGGCATTCGCCGTCGAGCACCAGGAGGC
CCTGGATCGCTGTGTGGCCCACGTGCTCGGCGAACGGGCGCGGCTGGTCGAGGAGCTGCCGGCGGTCCCCGGTGTCGAGC
AGGTCTGGCCGACGCAGACCAACTTCCTCACCTTCCGGGTGCCGCAGGGCAGTGCCGATGCCGTGCACCGTGGTCTGCTC
GATCGAGGGGTCCTGATCAAGCGCCTGCACGGCAGCCATCCGCGGCTGGAGGACTGCCTGCGGGTGACGGTCGGTCGCCC
CGAGGAGAACAACCGCTTCCTCGAGGCGCTGGCCGAGACCCTCGCCGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCAGCACTGGCCGGGACCGCCGCGGTGATGGCACGGGGCGAGGGACTGACCGCCCATGCCCGCTCAGCGGAGTACCGCGG
CCAGGGGGAGGAGCGCAGCG

Downstream 100 bases:

>100_bases
GCCGCGGCTGCCCCAGCGCCGGCCAGTCTGGCCGGGGCGTTGTCGATTAGCGCCGCCCGGGGTGGCTGGGCTGCTGCATG
TCCGGCCGCTCACCGAGGGT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTEVEARVARWVRPQVQALEAYQVAEPGKAIKLDAMESPWAWPGALEEAWLERMRSVSVNRYPDPAARRLKPLLREGLGV
PEGAELLLGNGSDELIQLIDLAVAGSGRTVMAPGPSFAMYRIIAEYTGAEYVEVPLDAEFGLDLAATREAVSAYNPAVTY
LAHPNNPTGNGLDLDAVAELVAQSDGLVVVDEAYAPYADSSFLPRVLEFPNCLVLRTLSKVGLAGLRVGVLIGHPAWIDQ
LEKCRLPYNLGSLAQASAAFAVEHQEALDRCVAHVLGERARLVEELPAVPGVEQVWPTQTNFLTFRVPQGSADAVHRGLL
DRGVLIKRLHGSHPRLEDCLRVTVGRPEENNRFLEALAETLAVAA

Sequences:

>Translated_365_residues
MTEVEARVARWVRPQVQALEAYQVAEPGKAIKLDAMESPWAWPGALEEAWLERMRSVSVNRYPDPAARRLKPLLREGLGV
PEGAELLLGNGSDELIQLIDLAVAGSGRTVMAPGPSFAMYRIIAEYTGAEYVEVPLDAEFGLDLAATREAVSAYNPAVTY
LAHPNNPTGNGLDLDAVAELVAQSDGLVVVDEAYAPYADSSFLPRVLEFPNCLVLRTLSKVGLAGLRVGVLIGHPAWIDQ
LEKCRLPYNLGSLAQASAAFAVEHQEALDRCVAHVLGERARLVEELPAVPGVEQVWPTQTNFLTFRVPQGSADAVHRGLL
DRGVLIKRLHGSHPRLEDCLRVTVGRPEENNRFLEALAETLAVAA
>Mature_364_residues
TEVEARVARWVRPQVQALEAYQVAEPGKAIKLDAMESPWAWPGALEEAWLERMRSVSVNRYPDPAARRLKPLLREGLGVP
EGAELLLGNGSDELIQLIDLAVAGSGRTVMAPGPSFAMYRIIAEYTGAEYVEVPLDAEFGLDLAATREAVSAYNPAVTYL
AHPNNPTGNGLDLDAVAELVAQSDGLVVVDEAYAPYADSSFLPRVLEFPNCLVLRTLSKVGLAGLRVGVLIGHPAWIDQL
EKCRLPYNLGSLAQASAAFAVEHQEALDRCVAHVLGERARLVEELPAVPGVEQVWPTQTNFLTFRVPQGSADAVHRGLLD
RGVLIKRLHGSHPRLEDCLRVTVGRPEENNRFLEALAETLAVAA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=325, Percent_Identity=33.8461538461538, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788722, Length=210, Percent_Identity=29.0476190476191, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322075, Length=385, Percent_Identity=30.6493506493506, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39644; Mature: 39512

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVEARVARWVRPQVQALEAYQVAEPGKAIKLDAMESPWAWPGALEEAWLERMRSVSVN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
RYPDPAARRLKPLLREGLGVPEGAELLLGNGSDELIQLIDLAVAGSGRTVMAPGPSFAMY
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCHHHH
RIIAEYTGAEYVEVPLDAEFGLDLAATREAVSAYNPAVTYLAHPNNPTGNGLDLDAVAEL
HHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHH
VAQSDGLVVVDEAYAPYADSSFLPRVLEFPNCLVLRTLSKVGLAGLRVGVLIGHPAWIDQ
HHCCCCEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCHHHHEEEEEECCHHHHHH
LEKCRLPYNLGSLAQASAAFAVEHQEALDRCVAHVLGERARLVEELPAVPGVEQVWPTQT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
NFLTFRVPQGSADAVHRGLLDRGVLIKRLHGSHPRLEDCLRVTVGRPEENNRFLEALAET
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
LAVAA
HHHCC
>Mature Secondary Structure 
TEVEARVARWVRPQVQALEAYQVAEPGKAIKLDAMESPWAWPGALEEAWLERMRSVSVN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
RYPDPAARRLKPLLREGLGVPEGAELLLGNGSDELIQLIDLAVAGSGRTVMAPGPSFAMY
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCHHHH
RIIAEYTGAEYVEVPLDAEFGLDLAATREAVSAYNPAVTYLAHPNNPTGNGLDLDAVAEL
HHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHH
VAQSDGLVVVDEAYAPYADSSFLPRVLEFPNCLVLRTLSKVGLAGLRVGVLIGHPAWIDQ
HHCCCCEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCHHHHEEEEEECCHHHHHH
LEKCRLPYNLGSLAQASAAFAVEHQEALDRCVAHVLGERARLVEELPAVPGVEQVWPTQT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
NFLTFRVPQGSADAVHRGLLDRGVLIKRLHGSHPRLEDCLRVTVGRPEENNRFLEALAET
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
LAVAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA