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The map label for this gene is ppa [H]

Identifier: 121998784

GI number: 121998784

Start: 2209058

End: 2209588

Strand: Reverse

Name: ppa [H]

Synonym: Hhal_2005

Alternate gene names: 121998784

Gene position: 2209588-2209058 (Counterclockwise)

Preceding gene: 121998789

Following gene: 121998783

Centisome position: 82.49

GC content: 64.6

Gene sequence:

>531_bases
ATGAGCCTCGATTCCGTGCCCGCCGGGCGGTCGATTCCGGACGATATTAACGTCGTCATCGAGATCCCGCTCCACGGCGG
CCCCGTGAAGTACGAAGTGGATAAAGAGACGGGCACCCTCACCGTCGATCGCATCATGGCCACGGCGATGCACTACCCGT
GCAACTACGGCTTCGTGCCGCAGACGCTGGCGGATGACGGCGACCCGGTGGACGCGCTGGTGATCACCCCGCTGCCGCTG
GTGGCCGGCTCGGTGATCCGCTGCCGTCCGGTGGGCGTGCTGGAAATGGCCGATGAGTCGGGGGAGGACGCCAAGCTGAT
CGCTGTGCCGGTGGACAAGCTGACCACCGATTATAGCGAGGTGAAGGGCCCCGACGACCTGTCGCCGCGCCTGTTGCAGG
AGATCAGCCATTTCTTCGAGCACTATAAGGATCTCGAGCCCGGGAAGTGGGTGCAGGTGCGCGACTGGAAGGGTGCCGAC
GCCGCGCGAGCCGAGATCGAGCACGCGGTGTCCAACTACCAGAATCAGTAG

Upstream 100 bases:

>100_bases
CCGTAACGCCGGTTGCCGCGGCGCAGCAACGGCGTTAAAGTTCGCCCCTGTCTGGCCGTTCCATGGTCATAAACAGTCCT
CTACTGAACGGAGAAACTGC

Downstream 100 bases:

>100_bases
CAGCGCAGGAGCGTTGCCCGGCTCAGGGGGCCAGCGGAGCGGCCGATCACCCTTGAAGCGGTATCGACGTTCGGAGGTGG
TGAGCGATGGCTCGCGCCCT

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSLDSVPAGRSIPDDINVVIEIPLHGGPVKYEVDKETGTLTVDRIMATAMHYPCNYGFVPQTLADDGDPVDALVITPLPL
VAGSVIRCRPVGVLEMADESGEDAKLIAVPVDKLTTDYSEVKGPDDLSPRLLQEISHFFEHYKDLEPGKWVQVRDWKGAD
AARAEIEHAVSNYQNQ

Sequences:

>Translated_176_residues
MSLDSVPAGRSIPDDINVVIEIPLHGGPVKYEVDKETGTLTVDRIMATAMHYPCNYGFVPQTLADDGDPVDALVITPLPL
VAGSVIRCRPVGVLEMADESGEDAKLIAVPVDKLTTDYSEVKGPDDLSPRLLQEISHFFEHYKDLEPGKWVQVRDWKGAD
AARAEIEHAVSNYQNQ
>Mature_175_residues
SLDSVPAGRSIPDDINVVIEIPLHGGPVKYEVDKETGTLTVDRIMATAMHYPCNYGFVPQTLADDGDPVDALVITPLPLV
AGSVIRCRPVGVLEMADESGEDAKLIAVPVDKLTTDYSEVKGPDDLSPRLLQEISHFFEHYKDLEPGKWVQVRDWKGADA
ARAEIEHAVSNYQNQ

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=176, Percent_Identity=60.7954545454545, Blast_Score=226, Evalue=7e-61,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19296; Mature: 19165

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDSVPAGRSIPDDINVVIEIPLHGGPVKYEVDKETGTLTVDRIMATAMHYPCNYGFVP
CCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCC
QTLADDGDPVDALVITPLPLVAGSVIRCRPVGVLEMADESGEDAKLIAVPVDKLTTDYSE
CHHCCCCCCCCEEEECCCHHHHCCEEEECCCCEEEECCCCCCCCEEEEEEHHHHHCCHHH
VKGPDDLSPRLLQEISHFFEHYKDLEPGKWVQVRDWKGADAARAEIEHAVSNYQNQ
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLDSVPAGRSIPDDINVVIEIPLHGGPVKYEVDKETGTLTVDRIMATAMHYPCNYGFVP
CCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCC
QTLADDGDPVDALVITPLPLVAGSVIRCRPVGVLEMADESGEDAKLIAVPVDKLTTDYSE
CHHCCCCCCCCEEEECCCHHHHCCEEEECCCCEEEECCCCCCCCEEEEEEHHHHHCCHHH
VKGPDDLSPRLLQEISHFFEHYKDLEPGKWVQVRDWKGADAARAEIEHAVSNYQNQ
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]