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The map label for this gene is prmA

Identifier: 121998782

GI number: 121998782

Start: 2207745

End: 2208626

Strand: Reverse

Name: prmA

Synonym: Hhal_2003

Alternate gene names: 121998782

Gene position: 2208626-2207745 (Counterclockwise)

Preceding gene: 121998783

Following gene: 121998781

Centisome position: 82.46

GC content: 70.86

Gene sequence:

>882_bases
GTGGCGCAGTTGCAAGTCACGCTGGAGGTGGCGGCCGGCGACCTCGACGCCGTGGATGGCGCACTGGAGTTGGCCGGGGC
GCTGTCCCAGACCTATCAGGCCGACGACGGCACCGTGCTCCTCGAGCCCGGGGTGGGCGAGCACCCGCTGTGGGAGCAGG
TGCGGGTCGATGCGCTTTTTCCCCCTGAGACCGACCCCGATGCCCTGCACACCTTGCTGGCCGGGCAGCTGGGGGAGCGG
CTGCGGGGCTGGCAGGCCGAGACGCTGGAGGACCGTGCCTGGGAGCGTGAGTGGCTGGACCACTTTCGGCCGATGGCCTT
CGGCGAGCGCCTGTGGATCGTCCCCACCGGGGCCGAGCCCGAGCTGCCTGCCGGCGCGGTGCCGATCCACCTCGATCCGG
GCCTGGCCTTCGGTACCGGGACCCATGAGACCACGGCGCTGTGCCTGGAGTGGCTGGACGGCGAGCCCATAGCGGGGCGC
AACGGCCTGGATTACGGCGCCGGATCCGGCATCCTGGCCGTGGCGGCGGTGCGTCTGGGGGCGGCCTGCTGCATGGCCGT
CGATAACGATCCTCAGGCGGTGGTCGCCAGCCGCGAGAATGCCGAGCGCAACGGCGTGGCCGAGGATGTCCCGTCTTATG
CCGTCGATCAGCGTCCGGCGTATTGCGCCGATTTCCTTGTCGCCAATATCCTTGCCTCGACGCTGGTGGATCTGGCCGAT
GAGCTGCGCGATGGGGTCCGTGTCGGCGGACGCCTGGCGCTCTCCGGGATCCTCCGGGGGCAGGAGCAGCAGGTCATGGA
TGCCTTCCAGGGCGGCATCGCCTGGGATGCGCCGCGGTGCTGCGGCGACTGGGTGCTGGTCAGCGGCACCCGTACCGCCT
GA

Upstream 100 bases:

>100_bases
GCGCGTGGTCTCGGGGTTCGAGCGCGATGGCTGCTTCTACACCCGTGAGCAGGCCGCCTGCTTCGTGGTCCCGCCCACTC
CGCGACAAGGCTCCTGACTC

Downstream 100 bases:

>100_bases
ACGTCGGTCTCCGGATTCTCCAACAACGAGGGAAGCCCGTGTACACCCAGTGCCCTGGATGCGGGACGATCTTCGCGCTG
CGTGCCTGGCAGCTCCGTCA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAQLQVTLEVAAGDLDAVDGALELAGALSQTYQADDGTVLLEPGVGEHPLWEQVRVDALFPPETDPDALHTLLAGQLGER
LRGWQAETLEDRAWEREWLDHFRPMAFGERLWIVPTGAEPELPAGAVPIHLDPGLAFGTGTHETTALCLEWLDGEPIAGR
NGLDYGAGSGILAVAAVRLGAACCMAVDNDPQAVVASRENAERNGVAEDVPSYAVDQRPAYCADFLVANILASTLVDLAD
ELRDGVRVGGRLALSGILRGQEQQVMDAFQGGIAWDAPRCCGDWVLVSGTRTA

Sequences:

>Translated_293_residues
MAQLQVTLEVAAGDLDAVDGALELAGALSQTYQADDGTVLLEPGVGEHPLWEQVRVDALFPPETDPDALHTLLAGQLGER
LRGWQAETLEDRAWEREWLDHFRPMAFGERLWIVPTGAEPELPAGAVPIHLDPGLAFGTGTHETTALCLEWLDGEPIAGR
NGLDYGAGSGILAVAAVRLGAACCMAVDNDPQAVVASRENAERNGVAEDVPSYAVDQRPAYCADFLVANILASTLVDLAD
ELRDGVRVGGRLALSGILRGQEQQVMDAFQGGIAWDAPRCCGDWVLVSGTRTA
>Mature_292_residues
AQLQVTLEVAAGDLDAVDGALELAGALSQTYQADDGTVLLEPGVGEHPLWEQVRVDALFPPETDPDALHTLLAGQLGERL
RGWQAETLEDRAWEREWLDHFRPMAFGERLWIVPTGAEPELPAGAVPIHLDPGLAFGTGTHETTALCLEWLDGEPIAGRN
GLDYGAGSGILAVAAVRLGAACCMAVDNDPQAVVASRENAERNGVAEDVPSYAVDQRPAYCADFLVANILASTLVDLADE
LRDGVRVGGRLALSGILRGQEQQVMDAFQGGIAWDAPRCCGDWVLVSGTRTA

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=300, Percent_Identity=43.3333333333333, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_HALHL (A1WYK5)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003569.1
- ProteinModelPortal:   A1WYK5
- SMR:   A1WYK5
- STRING:   A1WYK5
- GeneID:   4711370
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2003
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   DERTELP
- PhylomeDB:   A1WYK5
- ProtClustDB:   CLSK727186
- BioCyc:   HHAL349124:HHAL_2003-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31158; Mature: 31027

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLQVTLEVAAGDLDAVDGALELAGALSQTYQADDGTVLLEPGVGEHPLWEQVRVDALF
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHEEEEEC
PPETDPDALHTLLAGQLGERLRGWQAETLEDRAWEREWLDHFRPMAFGERLWIVPTGAEP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCEEEEEECCCCC
ELPAGAVPIHLDPGLAFGTGTHETTALCLEWLDGEPIAGRNGLDYGAGSGILAVAAVRLG
CCCCCCEEEEECCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AACCMAVDNDPQAVVASRENAERNGVAEDVPSYAVDQRPAYCADFLVANILASTLVDLAD
HHHEEEECCCCCEEEECCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ELRDGVRVGGRLALSGILRGQEQQVMDAFQGGIAWDAPRCCGDWVLVSGTRTA
HHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
AQLQVTLEVAAGDLDAVDGALELAGALSQTYQADDGTVLLEPGVGEHPLWEQVRVDALF
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHEEEEEC
PPETDPDALHTLLAGQLGERLRGWQAETLEDRAWEREWLDHFRPMAFGERLWIVPTGAEP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCEEEEEECCCCC
ELPAGAVPIHLDPGLAFGTGTHETTALCLEWLDGEPIAGRNGLDYGAGSGILAVAAVRLG
CCCCCCEEEEECCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AACCMAVDNDPQAVVASRENAERNGVAEDVPSYAVDQRPAYCADFLVANILASTLVDLAD
HHHEEEECCCCCEEEECCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ELRDGVRVGGRLALSGILRGQEQQVMDAFQGGIAWDAPRCCGDWVLVSGTRTA
HHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA