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The map label for this gene is mdtA [H]

Identifier: 121998518

GI number: 121998518

Start: 1908673

End: 1909773

Strand: Reverse

Name: mdtA [H]

Synonym: Hhal_1739

Alternate gene names: 121998518

Gene position: 1909773-1908673 (Counterclockwise)

Preceding gene: 121998519

Following gene: 121998517

Centisome position: 71.3

GC content: 69.57

Gene sequence:

>1101_bases
ATGCGTCCCGCTTACCAGATCCTCTTCGCTGCCCTGCTGATTGCCGGGGTGGCTTTCGGCGGTTATTGGCTGACCCGCGG
CGAGCCGGCGTCCCAGGCAGGTCCCCCCGCAGGGCGCGAAGTGGTGGTGGAGGCCGCCGATGCCGAGCGGGCCGTGATCC
GGGACACCTTCCGGGCGACGGGAACCGCCCGTGCCCGGGAGGCCTTGGATGTGGTGACCGAAACGGCGGGCCGGATCACC
GCCATCGGTTTCGAGGAAGGCGCGGCAGTGGAAGCCGGGCAGATCCTGCTTGAGCTCGACGCCGAGCGCGAGCGGGCGGC
CCTGGAGGAGGCCCGGGCCCACCTAGAGGATGTGCAGGCACAGCTGCGTCGCGCTCGTACCTTGCGGGAGACCGGGGATG
TCACCGAGCAGGATGTGGACACCCTGGCAGCTGCTGTCGCCGTGGCCAGTGCCCAGGTCCGGGTGGCCGAGGTCCAACTC
CGCGAGCGCCGCATTCACGCCCCTTTCGCGGGCGTGGTCGGTATGCGCGGGCTGAGCCTCGGTGCCTACGTCGACCCGCA
GACCGTGGTGACCACCCTGGATGATACCGAGATCCTGCGGCTTGTCTTTACCGTTCCCGAGCGCCTGCTCGGGCGACTCG
AGACCGGCCTGGCGGTGACGGCCGGCAGTGCCGGATTTCCCGAGCACCGTTTCTCCGGGGTACTGCACCGGATCGACAGC
CGGATCGATCCGGTGACCCGGACCCTGCGCCTGGAGTCCGAGATCGACAACCGGGACGGCCGCCTCAAACCCGGGATGTT
CCTGCAGGTGGAGCTGGAACTCGATCGCCGCCAGGCCGTTGTCATCCCGGAAGAGGCTCTGATCCTCGACGGGCCCCGAC
GCTACGTCTACCGCATCACCGACGGTGTCGCCCGGCAGGTGGATGTGGAGATCGGGCAGCGTCAGAACGGCCGGGTGGAG
ATCAGCGCCGGACTCGAGCCCGCGGATCGGGTGGTCGCCCTGGGCCACCAGCGTCTGAGTGACGGCACCCGGGTCCGGGT
ACGTAACCGTCCGGCCGGTGATGCGGCGAATGGCAGTGGCTTGGCCGAGGCGGCCCGTTGA

Upstream 100 bases:

>100_bases
CCAAGCTTTCATCCAGTGAGCGGGTGGAGCGCGTATGGCGCGGCACATAAGGGGCGGCTAATATAGCCGTGGCCATCCAC
GGCCCCGGCCAGGAGTCACC

Downstream 100 bases:

>100_bases
TCCTCTCCGACATTGCGATCCGTCGTCCCGTCCTGGCCACCGTGGCCAGCGTGTTGATCGTCGTCCTCGGCATCGCCTCC
CTCGCTCAGTTGCCGGTACG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRPAYQILFAALLIAGVAFGGYWLTRGEPASQAGPPAGREVVVEAADAERAVIRDTFRATGTARAREALDVVTETAGRIT
AIGFEEGAAVEAGQILLELDAERERAALEEARAHLEDVQAQLRRARTLRETGDVTEQDVDTLAAAVAVASAQVRVAEVQL
RERRIHAPFAGVVGMRGLSLGAYVDPQTVVTTLDDTEILRLVFTVPERLLGRLETGLAVTAGSAGFPEHRFSGVLHRIDS
RIDPVTRTLRLESEIDNRDGRLKPGMFLQVELELDRRQAVVIPEEALILDGPRRYVYRITDGVARQVDVEIGQRQNGRVE
ISAGLEPADRVVALGHQRLSDGTRVRVRNRPAGDAANGSGLAEAAR

Sequences:

>Translated_366_residues
MRPAYQILFAALLIAGVAFGGYWLTRGEPASQAGPPAGREVVVEAADAERAVIRDTFRATGTARAREALDVVTETAGRIT
AIGFEEGAAVEAGQILLELDAERERAALEEARAHLEDVQAQLRRARTLRETGDVTEQDVDTLAAAVAVASAQVRVAEVQL
RERRIHAPFAGVVGMRGLSLGAYVDPQTVVTTLDDTEILRLVFTVPERLLGRLETGLAVTAGSAGFPEHRFSGVLHRIDS
RIDPVTRTLRLESEIDNRDGRLKPGMFLQVELELDRRQAVVIPEEALILDGPRRYVYRITDGVARQVDVEIGQRQNGRVE
ISAGLEPADRVVALGHQRLSDGTRVRVRNRPAGDAANGSGLAEAAR
>Mature_366_residues
MRPAYQILFAALLIAGVAFGGYWLTRGEPASQAGPPAGREVVVEAADAERAVIRDTFRATGTARAREALDVVTETAGRIT
AIGFEEGAAVEAGQILLELDAERERAALEEARAHLEDVQAQLRRARTLRETGDVTEQDVDTLAAAVAVASAQVRVAEVQL
RERRIHAPFAGVVGMRGLSLGAYVDPQTVVTTLDDTEILRLVFTVPERLLGRLETGLAVTAGSAGFPEHRFSGVLHRIDS
RIDPVTRTLRLESEIDNRDGRLKPGMFLQVELELDRRQAVVIPEEALILDGPRRYVYRITDGVARQVDVEIGQRQNGRVE
ISAGLEPADRVVALGHQRLSDGTRVRVRNRPAGDAANGSGLAEAAR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=336, Percent_Identity=30.952380952381, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081796, Length=359, Percent_Identity=26.7409470752089, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789929, Length=311, Percent_Identity=24.4372990353698, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786668, Length=339, Percent_Identity=24.4837758112094, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39664; Mature: 39664

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAYQILFAALLIAGVAFGGYWLTRGEPASQAGPPAGREVVVEAADAERAVIRDTFRAT
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHC
GTARAREALDVVTETAGRITAIGFEEGAAVEAGQILLELDAERERAALEEARAHLEDVQA
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
QLRRARTLRETGDVTEQDVDTLAAAVAVASAQVRVAEVQLRERRIHAPFAGVVGMRGLSL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
GAYVDPQTVVTTLDDTEILRLVFTVPERLLGRLETGLAVTAGSAGFPEHRFSGVLHRIDS
CCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
RIDPVTRTLRLESEIDNRDGRLKPGMFLQVELELDRRQAVVIPEEALILDGPRRYVYRIT
HCCHHHHHEEEHHHCCCCCCCCCCCEEEEEEEEECCCEEEEECCCEEEEECCCCEEEEEC
DGVARQVDVEIGQRQNGRVEISAGLEPADRVVALGHQRLSDGTRVRVRNRPAGDAANGSG
CCHHHEEEHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LAEAAR
HHHHCC
>Mature Secondary Structure
MRPAYQILFAALLIAGVAFGGYWLTRGEPASQAGPPAGREVVVEAADAERAVIRDTFRAT
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHC
GTARAREALDVVTETAGRITAIGFEEGAAVEAGQILLELDAERERAALEEARAHLEDVQA
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
QLRRARTLRETGDVTEQDVDTLAAAVAVASAQVRVAEVQLRERRIHAPFAGVVGMRGLSL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
GAYVDPQTVVTTLDDTEILRLVFTVPERLLGRLETGLAVTAGSAGFPEHRFSGVLHRIDS
CCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHH
RIDPVTRTLRLESEIDNRDGRLKPGMFLQVELELDRRQAVVIPEEALILDGPRRYVYRIT
HCCHHHHHEEEHHHCCCCCCCCCCCEEEEEEEEECCCEEEEECCCEEEEECCCCEEEEEC
DGVARQVDVEIGQRQNGRVEISAGLEPADRVVALGHQRLSDGTRVRVRNRPAGDAANGSG
CCHHHEEEHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LAEAAR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA