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The map label for this gene is tadA [H]

Identifier: 121998459

GI number: 121998459

Start: 1833812

End: 1834240

Strand: Reverse

Name: tadA [H]

Synonym: Hhal_1680

Alternate gene names: 121998459

Gene position: 1834240-1833812 (Counterclockwise)

Preceding gene: 121998460

Following gene: 121998458

Centisome position: 68.48

GC content: 70.63

Gene sequence:

>429_bases
ATGGCGCGAGCGCTGGAGTTGGCGCGATATGCCGCGGACCAGGGCGAGGTGCCCGTGGGGGCGGTGGTGGTCCGCGACGG
GGTACTGCTCGGCGAAGGGAGGAACCAGCCGATCGTCAGCCGCGATCCAACCGCCCATGCCGAGATCAACGCGCTGCGCG
CGGCCGGTCAGGCCGCGGGGGCGTATCGCCTCCCCGGGGCAACGCTCTACGTCACCCTCGAGCCGTGCTTCATGTGTGCC
GGGGCATTGATCCACGCCCGCATCGAGCGCCTGGTCTACGGCGCCGCGGATCCCAAAACCGGTGCCTGTGGGGGGCAGTT
CGACCTGCTCGGTCTGCCCGGGCATAACCATCGGGTGGAGGTGACCGCTGGCGTCTCCGGCGAGGCGGCCGCCGGGCTGC
TGCGTGAATTCTTTCGCGCCCGGCGTTAA

Upstream 100 bases:

>100_bases
ACGAGATCGACGGCATCTCCCGCGTTGTCTACGACATCTCGGGCAAACCTCCGGCGACCATCGAGTGGGAGTGAGTGGGG
CGCGCGCCGATGCGGCCTGG

Downstream 100 bases:

>100_bases
CCCCGGCCGCGTCGACGGTCTGGCTCCGGCGCGGCTATAGTCAGAACATGCACGACGACGCCACGACCATCGTTCCGTTC
CGTGGGGGCGCGCTGGAGCG

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARALELARYAADQGEVPVGAVVVRDGVLLGEGRNQPIVSRDPTAHAEINALRAAGQAAGAYRLPGATLYVTLEPCFMCA
GALIHARIERLVYGAADPKTGACGGQFDLLGLPGHNHRVEVTAGVSGEAAAGLLREFFRARR

Sequences:

>Translated_142_residues
MARALELARYAADQGEVPVGAVVVRDGVLLGEGRNQPIVSRDPTAHAEINALRAAGQAAGAYRLPGATLYVTLEPCFMCA
GALIHARIERLVYGAADPKTGACGGQFDLLGLPGHNHRVEVTAGVSGEAAAGLLREFFRARR
>Mature_141_residues
ARALELARYAADQGEVPVGAVVVRDGVLLGEGRNQPIVSRDPTAHAEINALRAAGQAAGAYRLPGATLYVTLEPCFMCAG
ALIHARIERLVYGAADPKTGACGGQFDLLGLPGHNHRVEVTAGVSGEAAAGLLREFFRARR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=148, Percent_Identity=31.7567567567568, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI19923945, Length=72, Percent_Identity=50, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI145693172, Length=142, Percent_Identity=59.1549295774648, Blast_Score=166, Evalue=4e-43,
Organism=Escherichia coli, GI1786616, Length=150, Percent_Identity=36.6666666666667, Blast_Score=64, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=40.2061855670103, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17555996, Length=79, Percent_Identity=43.0379746835443, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=151, Percent_Identity=33.7748344370861, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=35.8620689655172, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 14861; Mature: 14730

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARALELARYAADQGEVPVGAVVVRDGVLLGEGRNQPIVSRDPTAHAEINALRAAGQAAG
CCHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCC
AYRLPGATLYVTLEPCFMCAGALIHARIERLVYGAADPKTGACGGQFDLLGLPGHNHRVE
EEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEE
VTAGVSGEAAAGLLREFFRARR
EEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARALELARYAADQGEVPVGAVVVRDGVLLGEGRNQPIVSRDPTAHAEINALRAAGQAAG
CHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCC
AYRLPGATLYVTLEPCFMCAGALIHARIERLVYGAADPKTGACGGQFDLLGLPGHNHRVE
EEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEE
VTAGVSGEAAAGLLREFFRARR
EEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]