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The map label for this gene is htpG

Identifier: 121998371

GI number: 121998371

Start: 1730162

End: 1732063

Strand: Reverse

Name: htpG

Synonym: Hhal_1592

Alternate gene names: 121998371

Gene position: 1732063-1730162 (Counterclockwise)

Preceding gene: 121998372

Following gene: 121998370

Centisome position: 64.67

GC content: 63.72

Gene sequence:

>1902_bases
ATGAGCGCAGATACGCAGAGCGAGACCCTCGAATTCCAGGCCGAGGTTCAGCAGCTGCTGAGCCTGATGATTCACTCGGT
GTACTCGAACCGGGAGGTCTTCCTCCGCGAGCTCATCTCCAACGCCTCGGATGCCATCGATAAGCTGCGCTTCGAGGCGC
TTCAGCAGGAATCCCTCTACGAAGACGATCCGGAACTCAAGATCCGCGTCGAGGCCGATCCAGAGGCCCGCACCGTCACC
GTGATCGACAACGGCATCGGCATGAGTCGCGAGGATGTGATCGAAAACCTCGGGACCATCGCCCACTCGGGGACCCGCCG
TTTCCTTGAGCAGCTGACGGGTGATCAGCACAAGGATGCGCAGCTGATCGGCCAGTTCGGTGTCGGATTTTATTCGGCCT
TTGTGGTCGCCGACCGGGTTGAGGTCTACACCCGCAAGGCCGGCGCCGCTGCAGCTGAGGGCGTGCGCTGGAGTTCTGAT
GGCCAGGGGGCCTACACCGTCGACACCGTCGAGCGCGCCGAGCGCGGCACCGCCGTGGTGCTGCACCTCCCCGAGGCGCA
GCAGGAGTTCTGCGACGACATGCGCCTGCGCCAGATCATCCGCAAGTACTCCGACCATATCTCGGTCCCCATCGAGATGC
CGGTGCGCAACGCGGACCAGGGTGATGACGCGGACAGTGAGGCCGAGGCCCCGCAGTGGGAGATCGTCAACCGCGCCTCG
GCGCTGTGGATGCGGCCGAAGAGCGAGATCTCCGAGGAAGATTATCAAGAGCTGTACAAGCACGTCGCCCACGACTTCGA
CGATCCCCTGACCTGGATCCACAACCATGTCGAGGGGCGCCAGTCCTATGTCTCGTTGCTCTACATCCCCAAGCGCCCTC
CGTTCGATCTCTACGAGCAGAAGCCGGCCCACGGGGTCAAGCTCTATGTGCGGCGCGTCTTCATCACCGAGGATACGGAG
CACCTGCTGCCGCGCTACCTGCGTTTCGTCCGGGGCGTCATCGACTCGGACGATCTGCCGCTGAACATCTCCCGGGAGAT
GTTGCAGCACAACCCGATGATCAGCTCGCTGCGTTCGGCCTCGGTCAAGCGCATCCTCGACCGGCTCGAGTGCATGGCGA
AGAACGAGCCGGAGGACTACGCCACCTTCTGGCAGGCCTTTGGGCGGGTCTTCAAGGAGGGCATCGCCGAGGATCCGGGC
AACCGGGAGCGCATCGCGCGGCTGCTGCGCTTCTCCTCGACCCACGAAGAGAAGGAGACGCCGGACGTCAGTCTGGACGA
CTACGTCGCCCGGATGAAGGACGGCCAGGAGAAGATCTACTACGTAACGGCGGAGAGCTTCAACGCCGCGCGGAATAGCC
CGCATCTGGAGATCTTCCGTCGCCACGGCATCGAGGTCCTGCTGCTCCCGGATCCCGTCGACGAGTGGTTGGTGGCCCAT
CTGCACGAGTACGATGGCAAGCAGCTGGCGTCGGTGGCCAAGGGTGAGCTCGATCTGGAGGCCCTCGGCGAAGAGGACGA
CAAGCAGGCGCGGCAGGAGAAGGAGCAGGCCTACGAAGACCTCTGTAAGCGTCTGGGTGAGACCCTGGGTGAGCGGGTCA
GCGAGGTCCGGGTCAGCCACCGCCTGACCGATTCGCCGGCCTGCCTGGTCGTCGGCGAGTACGATTTCGGCATGGGCATG
CAGCGCCTGTTGCAGGCTGCCGGGCATCAGCTTCCTGCAGGTCAACCGGCGCTGGAGGTTAATCCGGATCACTCCGTGAT
TGAGCGATTGGCGACGGAGTCGGGACAGCGCTTCGAAGACTGGGCCTTGACGCTCTACGAGCAGTCGCTGCTCGCCGAGG
GAGGGCAGCTGGAGGATCCAGCCGCGTATGTCCGACGTGTTAATAACCTCCTGGCTGGCTAG

Upstream 100 bases:

>100_bases
AAAGCCGGTCAGGCGTTCCCACATCCGGTCGACACAACCCGCCGCCGGGATCCGGCGAGCGAGCCCACGTGTTCAACGAG
AGGAGCAGGGGATCCCATCC

Downstream 100 bases:

>100_bases
GGGAGTGTGAGGATGGCATCGAGACCTCCGGACGAGCCGTCGACGGCGGCCTTTGAACTCAAGGGCCGCATGGCGACGCT
GACCGTGGTCCGGGTCCTGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLYEDDPELKIRVEADPEARTVT
VIDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDAQLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSD
GQGAYTVDTVERAERGTAVVLHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRAS
ALWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQKPAHGVKLYVRRVFITEDTE
HLLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSASVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPG
NRERIARLLRFSSTHEEKETPDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAH
LHEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSHRLTDSPACLVVGEYDFGMGM
QRLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFEDWALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG

Sequences:

>Translated_633_residues
MSADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLYEDDPELKIRVEADPEARTVT
VIDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDAQLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSD
GQGAYTVDTVERAERGTAVVLHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRAS
ALWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQKPAHGVKLYVRRVFITEDTE
HLLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSASVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPG
NRERIARLLRFSSTHEEKETPDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAH
LHEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSHRLTDSPACLVVGEYDFGMGM
QRLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFEDWALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG
>Mature_632_residues
SADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLYEDDPELKIRVEADPEARTVTV
IDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDAQLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSDG
QGAYTVDTVERAERGTAVVLHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRASA
LWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQKPAHGVKLYVRRVFITEDTEH
LLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSASVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPGN
RERIARLLRFSSTHEEKETPDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAHL
HEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSHRLTDSPACLVVGEYDFGMGMQ
RLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFEDWALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=683, Percent_Identity=38.506588579795, Blast_Score=462, Evalue=1e-130,
Organism=Homo sapiens, GI4507677, Length=682, Percent_Identity=35.9237536656891, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=36.2363919129082, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=39.7560975609756, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=39.7560975609756, Blast_Score=297, Evalue=2e-80,
Organism=Escherichia coli, GI1786679, Length=627, Percent_Identity=55.0239234449761, Blast_Score=712, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=670, Percent_Identity=38.5074626865672, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=35.8518518518519, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=34.6811819595645, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI115535167, Length=430, Percent_Identity=37.2093023255814, Blast_Score=280, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6325016, Length=690, Percent_Identity=38.1159420289855, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6323840, Length=685, Percent_Identity=38.2481751824818, Blast_Score=477, Evalue=1e-135,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=38.4502923976608, Blast_Score=490, Evalue=1e-138,
Organism=Drosophila melanogaster, GI21357739, Length=683, Percent_Identity=36.4568081991215, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24586016, Length=644, Percent_Identity=36.4906832298137, Blast_Score=391, Evalue=1e-109,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_HALHL (A1WXE4)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003158.1
- ProteinModelPortal:   A1WXE4
- STRING:   A1WXE4
- GeneID:   4709082
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1592
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   A1WXE4
- ProtClustDB:   PRK05218
- BioCyc:   HHAL349124:HHAL_1592-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71996; Mature: 71865

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EDDPELKIRVEADPEARTVTVIDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDA
CCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSDGQGAYTVDTVERAERGTAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEECCCCCCCEEHHHHHHHCCCCEEE
LHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRAS
EECCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
ALWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQ
HHHCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHC
KPAHGVKLYVRRVFITEDTEHLLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSA
CCCCCCEEHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHH
SVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPGNRERIARLLRFSSTHEEKET
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
PDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAH
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHH
LHEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSH
HHHCCCHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTDSPACLVVGEYDFGMGMQRLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFED
HCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHH
WALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EDDPELKIRVEADPEARTVTVIDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDA
CCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSDGQGAYTVDTVERAERGTAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEECCCCCCCEEHHHHHHHCCCCEEE
LHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRAS
EECCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
ALWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQ
HHHCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHC
KPAHGVKLYVRRVFITEDTEHLLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSA
CCCCCCEEHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHH
SVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPGNRERIARLLRFSSTHEEKET
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
PDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAH
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHH
LHEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSH
HHHCCCHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTDSPACLVVGEYDFGMGMQRLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFED
HCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHH
WALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA