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The map label for this gene is frr

Identifier: 121998245

GI number: 121998245

Start: 1579188

End: 1579745

Strand: Reverse

Name: frr

Synonym: Hhal_1463

Alternate gene names: 121998245

Gene position: 1579745-1579188 (Counterclockwise)

Preceding gene: 121998246

Following gene: 121998244

Centisome position: 58.98

GC content: 63.62

Gene sequence:

>558_bases
GTGATCGAAGATATCCAGGAAGACGCCGATCGCCGGATGGCCAAGGCCGTCGAGAGCCTCAAGCACGACCTGGCTCGGCT
GCGCACCGGGCGCGCCCACACCAGCCTGCTTGACCAGGTCAATGTCGAGTATTACGGCATGGAGGTGCCCATCAAGCAGG
CGGCCAATGTCAGCGTGGAGGATTCGCGTACGCTGGCCGTTACACCCTTCGAGAAGCACATGGTGCCTGCCATTGAGAAG
GCGATCATGGCCTCGAACCTGGGGCTGAGTCCAGTCTCGGCCGGGCAGGTCATCCGGGTGCCGCTGCCCTCACTGACCGA
AGACCGCCGCAAGGAGATGGTCCGCTTGGTCAAGAACGAGGCCGAGCAGGCCCGTGTCGCCATCCGCAACGTCCGCCGGG
ATGCCAATTCGGACCTTAAGGACCTCGCCAAGGGCAAGGACATCACCGAGGACGAGGAGCGCCGCGCCCAGGAGGCCATC
CAGAAGCTCACCGACCGGTATGTGGCGCAAGTCGACGACCTGCTCGAGGAGAAAGAACGCGAGCTCATGGAGGTCTGA

Upstream 100 bases:

>100_bases
TTGATATCACCAGCCCGGGTACCATGGTTGCCGCGGCCCGTGGCGAGCCGGTGGGTACCGTGGTCGATCCGGGCCTGCCC
AGCGCCCAGGAGGAATCATC

Downstream 100 bases:

>100_bases
GCGGGTCGTATGGCGGATACGAATGGGCCAGCCCAGATCAGTGAGCGGCTAGCCGGTGTCGAGTTGCCGCGCCATATCGC
CATCGTCATGGATGGCAACG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIEDIQEDADRRMAKAVESLKHDLARLRTGRAHTSLLDQVNVEYYGMEVPIKQAANVSVEDSRTLAVTPFEKHMVPAIEK
AIMASNLGLSPVSAGQVIRVPLPSLTEDRRKEMVRLVKNEAEQARVAIRNVRRDANSDLKDLAKGKDITEDEERRAQEAI
QKLTDRYVAQVDDLLEEKERELMEV

Sequences:

>Translated_185_residues
MIEDIQEDADRRMAKAVESLKHDLARLRTGRAHTSLLDQVNVEYYGMEVPIKQAANVSVEDSRTLAVTPFEKHMVPAIEK
AIMASNLGLSPVSAGQVIRVPLPSLTEDRRKEMVRLVKNEAEQARVAIRNVRRDANSDLKDLAKGKDITEDEERRAQEAI
QKLTDRYVAQVDDLLEEKERELMEV
>Mature_185_residues
MIEDIQEDADRRMAKAVESLKHDLARLRTGRAHTSLLDQVNVEYYGMEVPIKQAANVSVEDSRTLAVTPFEKHMVPAIEK
AIMASNLGLSPVSAGQVIRVPLPSLTEDRRKEMVRLVKNEAEQARVAIRNVRRDANSDLKDLAKGKDITEDEERRAQEAI
QKLTDRYVAQVDDLLEEKERELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=31.3333333333333, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=56.7567567567568, Blast_Score=216, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_HALHL (A1WX18)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003032.1
- ProteinModelPortal:   A1WX18
- SMR:   A1WX18
- STRING:   A1WX18
- GeneID:   4709736
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1463
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1WX18
- BioCyc:   HHAL349124:HHAL_1463-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20989; Mature: 20989

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDIQEDADRRMAKAVESLKHDLARLRTGRAHTSLLDQVNVEYYGMEVPIKQAANVSVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCCCCHHHHCCCCCC
DSRTLAVTPFEKHMVPAIEKAIMASNLGLSPVSAGQVIRVPLPSLTEDRRKEMVRLVKNE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AEQARVAIRNVRRDANSDLKDLAKGKDITEDEERRAQEAIQKLTDRYVAQVDDLLEEKER
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIEDIQEDADRRMAKAVESLKHDLARLRTGRAHTSLLDQVNVEYYGMEVPIKQAANVSVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCCCCHHHHCCCCCC
DSRTLAVTPFEKHMVPAIEKAIMASNLGLSPVSAGQVIRVPLPSLTEDRRKEMVRLVKNE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AEQARVAIRNVRRDANSDLKDLAKGKDITEDEERRAQEAIQKLTDRYVAQVDDLLEEKER
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA