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The map label for this gene is fabZ

Identifier: 121998239

GI number: 121998239

Start: 1571939

End: 1572430

Strand: Reverse

Name: fabZ

Synonym: Hhal_1457

Alternate gene names: 121998239

Gene position: 1572430-1571939 (Counterclockwise)

Preceding gene: 121998240

Following gene: 121998238

Centisome position: 58.71

GC content: 63.21

Gene sequence:

>492_bases
GTGACCGGATCTGAAGACGGAGGAGACAGCGTGAGCGAGCGTGACGCGCAAGGCGCAACGGACATCGAAGGCATCATGAA
CCTGCTGCCGCACCGGTATCCGCTGCTGCTGATCGACCGGGTGCTCGATTTCCAGCCCCACGAGCATCTGGCCAGCATCA
AGAATGTCACCATCAACGAGCCGTTCTTCGTCGGCCATTTCCCGCAGAAACCGGTGATGCCCGGCGTTCTGATCCTTGAA
TCGCTGGCCCAGGCCTGCGGCATGCTCGCGTTCAAGAGCGTCCAGGATACGCTGACCGACAACGACGTTCTCTATCTGGT
GGGGATCGATAAGGCGCGCTTCAAGCGCCCGGTTCAGCCCGGGGATCAGCTCCGCCACGACGTCTCGGTGCGCCGGGTGA
CGCGGGGCATCTGGATCTTCGAGGCCCGTGGCAGCGTCGACGGTGAGCTGGCTGCCGAGTGCGAGATCCGCTGCACGGTG
CGTACGGTTTGA

Upstream 100 bases:

>100_bases
TTAAGCTCTGCCGCTTGTAGCTCCGTCCGCGGGCGCGGGCAGCCTGCCGGAGCGGCAGGTGAGTCGGGCGGACGGAGGGC
GAGGGGCGGTACGCCCCGGT

Downstream 100 bases:

>100_bases
CGCGAATCCACCCGAACGCCCTGGTCGATCCCAAGGCTCGCCTCGGTGAAGAGGTCGAGGTGGGGCCGTTCAGCGTCATC
GGTCCGGATGTGGAGATCGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTGSEDGGDSVSERDAQGATDIEGIMNLLPHRYPLLLIDRVLDFQPHEHLASIKNVTINEPFFVGHFPQKPVMPGVLILE
SLAQACGMLAFKSVQDTLTDNDVLYLVGIDKARFKRPVQPGDQLRHDVSVRRVTRGIWIFEARGSVDGELAAECEIRCTV
RTV

Sequences:

>Translated_163_residues
MTGSEDGGDSVSERDAQGATDIEGIMNLLPHRYPLLLIDRVLDFQPHEHLASIKNVTINEPFFVGHFPQKPVMPGVLILE
SLAQACGMLAFKSVQDTLTDNDVLYLVGIDKARFKRPVQPGDQLRHDVSVRRVTRGIWIFEARGSVDGELAAECEIRCTV
RTV
>Mature_162_residues
TGSEDGGDSVSERDAQGATDIEGIMNLLPHRYPLLLIDRVLDFQPHEHLASIKNVTINEPFFVGHFPQKPVMPGVLILES
LAQACGMLAFKSVQDTLTDNDVLYLVGIDKARFKRPVQPGDQLRHDVSVRRVTRGIWIFEARGSVDGELAAECEIRCTVR
TV

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=53.2374100719424, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 18097; Mature: 17966

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSEDGGDSVSERDAQGATDIEGIMNLLPHRYPLLLIDRVLDFQPHEHLASIKNVTINE
CCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCC
PFFVGHFPQKPVMPGVLILESLAQACGMLAFKSVQDTLTDNDVLYLVGIDKARFKRPVQP
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCCC
GDQLRHDVSVRRVTRGIWIFEARGSVDGELAAECEIRCTVRTV
HHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
TGSEDGGDSVSERDAQGATDIEGIMNLLPHRYPLLLIDRVLDFQPHEHLASIKNVTINE
CCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCC
PFFVGHFPQKPVMPGVLILESLAQACGMLAFKSVQDTLTDNDVLYLVGIDKARFKRPVQP
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCCC
GDQLRHDVSVRRVTRGIWIFEARGSVDGELAAECEIRCTVRTV
HHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA