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The map label for this gene is rnhB

Identifier: 121998236

GI number: 121998236

Start: 1569409

End: 1569996

Strand: Reverse

Name: rnhB

Synonym: Hhal_1454

Alternate gene names: 121998236

Gene position: 1569996-1569409 (Counterclockwise)

Preceding gene: 121998237

Following gene: 121998235

Centisome position: 58.62

GC content: 70.07

Gene sequence:

>588_bases
GTGACCCCCTCGCGCGGTGCATGGGGGGTGGTGGGCGTTGACGAGGCCGGACGCGGACCCTGGGCAGGGCCGGTGGTTGC
CGCGGCGGTGGTCCTGGCGGAACCGATCGCCGGGGTTACCGACTCCAAACGGCTTTCCGCGCGGAGCCGCGAGCGCGCTG
CAGCGCTGATCCGTAGCGAGGCCGTGGCCTGGGGGGTAGGGCGGGCCGATGTTACCGAGATCGATGCCTTGAATATTCGT
CGTGCCACCTTCCTGGCCATGGCCCGGGCGGTGGCCGTGGTGGCCGAGACCAGCCCGATCGCCGAGGTGCTGGTGGATGG
TCGAGAGATCCCGGACGATCTGCCCGCCCCGGCGCGACCCGTAGTGGGTGGGGATGCGCTGGAGCCGGCCATCTCCGCAG
CCTCGATCCTGGCCAAGACCCTGCGTGACGCCGAGATGGTGCTGCTTGACGAAGCCTACCCGGGGTACGGTTTTGGGCGG
CACAAAGGGTACGGCACGGCCGAACATCGTCGGGCCCTTGAGGAGCTCGGTCCGTGCCCGATGCACCGGCGCAGTTTTGC
ACCGGTACGCCGGCTGCTCGGTGGCTGA

Upstream 100 bases:

>100_bases
CCGCCCGCCTGCAGCTGGTGGGCCGTTTTCGCCACCTCCACGAGACGCTGGCCCGGGGCGCCGATGCGCGGGCGGCGGAG
GCGGTTCTCGAGGTGCTGCA

Downstream 100 bases:

>100_bases
GCGCCGCAGCGCTCGATCCACCGGACTCGTTCCCGACCGCCACCCTGATATCCTGACGCGACCATGAGTGAAGACCCTCC
GCCCTTCGTCCACCTGCGCT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTPSRGAWGVVGVDEAGRGPWAGPVVAAAVVLAEPIAGVTDSKRLSARSRERAAALIRSEAVAWGVGRADVTEIDALNIR
RATFLAMARAVAVVAETSPIAEVLVDGREIPDDLPAPARPVVGGDALEPAISAASILAKTLRDAEMVLLDEAYPGYGFGR
HKGYGTAEHRRALEELGPCPMHRRSFAPVRRLLGG

Sequences:

>Translated_195_residues
MTPSRGAWGVVGVDEAGRGPWAGPVVAAAVVLAEPIAGVTDSKRLSARSRERAAALIRSEAVAWGVGRADVTEIDALNIR
RATFLAMARAVAVVAETSPIAEVLVDGREIPDDLPAPARPVVGGDALEPAISAASILAKTLRDAEMVLLDEAYPGYGFGR
HKGYGTAEHRRALEELGPCPMHRRSFAPVRRLLGG
>Mature_194_residues
TPSRGAWGVVGVDEAGRGPWAGPVVAAAVVLAEPIAGVTDSKRLSARSRERAAALIRSEAVAWGVGRADVTEIDALNIRR
ATFLAMARAVAVVAETSPIAEVLVDGREIPDDLPAPARPVVGGDALEPAISAASILAKTLRDAEMVLLDEAYPGYGFGRH
KGYGTAEHRRALEELGPCPMHRRSFAPVRRLLGG

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=187, Percent_Identity=55.0802139037433, Blast_Score=174, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_HALHL (A1WX09)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003023.1
- ProteinModelPortal:   A1WX09
- SMR:   A1WX09
- STRING:   A1WX09
- GeneID:   4710707
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1454
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   A1WX09
- ProtClustDB:   PRK00015
- BioCyc:   HHAL349124:HHAL_1454-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 20463; Mature: 20331

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSRGAWGVVGVDEAGRGPWAGPVVAAAVVLAEPIAGVTDSKRLSARSRERAAALIRSE
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AVAWGVGRADVTEIDALNIRRATFLAMARAVAVVAETSPIAEVLVDGREIPDDLPAPARP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
VVGGDALEPAISAASILAKTLRDAEMVLLDEAYPGYGFGRHKGYGTAEHRRALEELGPCP
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
MHRRSFAPVRRLLGG
CCHHHHHHHHHHHCC
>Mature Secondary Structure 
TPSRGAWGVVGVDEAGRGPWAGPVVAAAVVLAEPIAGVTDSKRLSARSRERAAALIRSE
CCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AVAWGVGRADVTEIDALNIRRATFLAMARAVAVVAETSPIAEVLVDGREIPDDLPAPARP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
VVGGDALEPAISAASILAKTLRDAEMVLLDEAYPGYGFGRHKGYGTAEHRRALEELGPCP
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
MHRRSFAPVRRLLGG
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA