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The map label for this gene is actR [H]

Identifier: 121998201

GI number: 121998201

Start: 1532190

End: 1532726

Strand: Reverse

Name: actR [H]

Synonym: Hhal_1419

Alternate gene names: 121998201

Gene position: 1532726-1532190 (Counterclockwise)

Preceding gene: 121998202

Following gene: 121998200

Centisome position: 57.22

GC content: 65.74

Gene sequence:

>537_bases
ATGTTGAACGGGCCATCGATCCTGATCATCGATGACGATACGACCTTCTCCCAGGTGCTGGGGCGCTCGCTCTCGCGCCG
GGGCTGCCACGTGGACTCGGCCGAGGAGCCCGAGACCGCCTTGCAGAAAGCGCGCAGTCAGCAGCCGCAGTACGTGGTGC
TGGATCTCAAGCTCGGTGAGCACTCGGGGCTCAATCTGGTCGAGCCCCTCAAGGATGCACTCCCGCAGGCCCGCATCCTG
GTGCTGACCGGATACGCGAGCATCCCCACCGCCGTGGAGGCGATTAAGCGTGGGGCTTACAACTACTTGCCCAAGCCCAC
GGATGCCGACACCGTGCTCGCGACCCTGGAAGGCAAGCCTGCCGCTGAGCCGGAAAAGCCGCCGCAGAAGCCGATGTCGC
TGCGCCGCCTCGAGTGGGAGCAGATCCAGCGGGTGCTCAATGAGCACGACGGCAACATCTCGGCGGCGGCCCGGGCGCTG
GGGATCCATCGTCGCACCCTGCAGCGCAAACTGAGCAAACGGCCGGTCAAGCAGTAG

Upstream 100 bases:

>100_bases
GAAGATCGAGGTCTCCCTCGAACGGCTGCGCGCGGACCACAACCGCGGCAGCGACTGAGGGAGAGAGCCGGTGAGGCTTG
AGGAGGAGAGGAGGTGAACC

Downstream 100 bases:

>100_bases
CCGCCTGCGATTTGCATGGGTATGAATGCTTCGCTATGTTGCCAGCTGAGGTCGATCACCGGCCTCGTCCATGCACGCAA
GGAGCCAAGCCAAGATGCGA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MLNGPSILIIDDDTTFSQVLGRSLSRRGCHVDSAEEPETALQKARSQQPQYVVLDLKLGEHSGLNLVEPLKDALPQARIL
VLTGYASIPTAVEAIKRGAYNYLPKPTDADTVLATLEGKPAAEPEKPPQKPMSLRRLEWEQIQRVLNEHDGNISAAARAL
GIHRRTLQRKLSKRPVKQ

Sequences:

>Translated_178_residues
MLNGPSILIIDDDTTFSQVLGRSLSRRGCHVDSAEEPETALQKARSQQPQYVVLDLKLGEHSGLNLVEPLKDALPQARIL
VLTGYASIPTAVEAIKRGAYNYLPKPTDADTVLATLEGKPAAEPEKPPQKPMSLRRLEWEQIQRVLNEHDGNISAAARAL
GIHRRTLQRKLSKRPVKQ
>Mature_178_residues
MLNGPSILIIDDDTTFSQVLGRSLSRRGCHVDSAEEPETALQKARSQQPQYVVLDLKLGEHSGLNLVEPLKDALPQARIL
VLTGYASIPTAVEAIKRGAYNYLPKPTDADTVLATLEGKPAAEPEKPPQKPMSLRRLEWEQIQRVLNEHDGNISAAARAL
GIHRRTLQRKLSKRPVKQ

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=37.8378378378378, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1788550, Length=104, Percent_Identity=29.8076923076923, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788905, Length=111, Percent_Identity=29.7297297297297, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19699; Mature: 19699

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNGPSILIIDDDTTFSQVLGRSLSRRGCHVDSAEEPETALQKARSQQPQYVVLDLKLGE
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECC
HSGLNLVEPLKDALPQARILVLTGYASIPTAVEAIKRGAYNYLPKPTDADTVLATLEGKP
CCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHCCCCCCCCCCCEEEEECCCC
AAEPEKPPQKPMSLRRLEWEQIQRVLNEHDGNISAAARALGIHRRTLQRKLSKRPVKQ
CCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNGPSILIIDDDTTFSQVLGRSLSRRGCHVDSAEEPETALQKARSQQPQYVVLDLKLGE
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECC
HSGLNLVEPLKDALPQARILVLTGYASIPTAVEAIKRGAYNYLPKPTDADTVLATLEGKP
CCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHCCCCCCCCCCCEEEEECCCC
AAEPEKPPQKPMSLRRLEWEQIQRVLNEHDGNISAAARALGIHRRTLQRKLSKRPVKQ
CCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]