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The map label for this gene is nhaA [H]

Identifier: 121998030

GI number: 121998030

Start: 1344836

End: 1345786

Strand: Reverse

Name: nhaA [H]

Synonym: Hhal_1240

Alternate gene names: 121998030

Gene position: 1345786-1344836 (Counterclockwise)

Preceding gene: 121998031

Following gene: 121998028

Centisome position: 50.24

GC content: 65.4

Gene sequence:

>951_bases
ATGAGCGAAGAGACGTCGGAGCGTGATGCGCTTCTGGAGCTGCTAAAGGAGAATATCCGCGAGCAACGTCGAGCACGGCG
CTGGCGCCTGATCACCCGCGGCGCCATCCTGGTGGTGGTCGTCCTAGTCGCCGTTTCGCTGGGGCGCCTGGACTTCGCCG
CGGACGAAGAAATCGGCCCGCATACGGCGGAGGTGCGCATCGACGGCCCGATCATGTCGGATTCCGCGGCCAGTGCCGAG
CAAGTTATCCGCGGGCTGGAGCGCGCCTTCGAGGCCGATGACGCAGCGGGTGTGGTGCTGCGTATCAACAGCCCGGGCGG
GAGCGCGGTGCATGCCCGGCAGATTTATCAGGAGATCCGGCGCCTGCGCGAGGAGTACGAGGACATCCCGGTCCACGCCG
TCATCGAAGATATCGGAACCTCCGGGGCTTATTACGTCGCCGCTGCTGCTGACCAGATCCACGTCAACGAGTCGAGCATC
GTCGGCTCGATCGGGGTCATCATGGGCAGCTTCGGCATCGGTGAGGCCCTGGAAAAACTCGGCATTGAGCGGCGGGTCTA
CACCGCTGGCGACGACAAGGCCTTCCTCGACCCCTTTGCCCCGGAGGATGAGGCCCATGTCGAACATGTGCGCACCATGC
TCGACGATATCCACGGCCAGTTCATTGCCGCCGTGCGCGACGGGCGCGGTGAGCAGATCGACGCGGCCGGTGCCGACGAG
GATCGCCTCTTCTCGGGGCTGATCTGGACCGGGCAGCAGAGCCTCGACAAAGGGCTGGCCGACGAGATTGGCAGCGTGCG
CAGCGTCGCCCGCGACGTGATCGGCGAGGAGGAGCTGGTCGACTATACGGCGCGGCGTGATTTTCTCTCGCAGCTTGCCG
AGCGTTTCGGCACCGCCGTCGGTCAGGGGGTCTACCAGTCGCTAGAGACGTTCGAGCACCAACCCCGCTGA

Upstream 100 bases:

>100_bases
ATCCGGATACCGGGGAACCCCTCTGTATCGAGGCGCCGCTCAGCGATGAGCTGAAGGCGGTCCTCGAACGGTTATCGCAT
TCACAAGACGAGGAGTCAGC

Downstream 100 bases:

>100_bases
TGCGGGCCCGTGAGCGGGTGCCCTGCCAGGCCACGGGGCCGCACCCCGGCAGGGCATCCGCTCAGGGCAGTCGATACCCC
TTGCCCCGGAGGAGGCGTGC

Product: peptidase S49

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSEETSERDALLELLKENIREQRRARRWRLITRGAILVVVVLVAVSLGRLDFAADEEIGPHTAEVRIDGPIMSDSAASAE
QVIRGLERAFEADDAAGVVLRINSPGGSAVHARQIYQEIRRLREEYEDIPVHAVIEDIGTSGAYYVAAAADQIHVNESSI
VGSIGVIMGSFGIGEALEKLGIERRVYTAGDDKAFLDPFAPEDEAHVEHVRTMLDDIHGQFIAAVRDGRGEQIDAAGADE
DRLFSGLIWTGQQSLDKGLADEIGSVRSVARDVIGEEELVDYTARRDFLSQLAERFGTAVGQGVYQSLETFEHQPR

Sequences:

>Translated_316_residues
MSEETSERDALLELLKENIREQRRARRWRLITRGAILVVVVLVAVSLGRLDFAADEEIGPHTAEVRIDGPIMSDSAASAE
QVIRGLERAFEADDAAGVVLRINSPGGSAVHARQIYQEIRRLREEYEDIPVHAVIEDIGTSGAYYVAAAADQIHVNESSI
VGSIGVIMGSFGIGEALEKLGIERRVYTAGDDKAFLDPFAPEDEAHVEHVRTMLDDIHGQFIAAVRDGRGEQIDAAGADE
DRLFSGLIWTGQQSLDKGLADEIGSVRSVARDVIGEEELVDYTARRDFLSQLAERFGTAVGQGVYQSLETFEHQPR
>Mature_315_residues
SEETSERDALLELLKENIREQRRARRWRLITRGAILVVVVLVAVSLGRLDFAADEEIGPHTAEVRIDGPIMSDSAASAEQ
VIRGLERAFEADDAAGVVLRINSPGGSAVHARQIYQEIRRLREEYEDIPVHAVIEDIGTSGAYYVAAAADQIHVNESSIV
GSIGVIMGSFGIGEALEKLGIERRVYTAGDDKAFLDPFAPEDEAHVEHVRTMLDDIHGQFIAAVRDGRGEQIDAAGADED
RLFSGLIWTGQQSLDKGLADEIGSVRSVARDVIGEEELVDYTARRDFLSQLAERFGTAVGQGVYQSLETFEHQPR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=240, Percent_Identity=29.5833333333333, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34666; Mature: 34535

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEETSERDALLELLKENIREQRRARRWRLITRGAILVVVVLVAVSLGRLDFAADEEIGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HTAEVRIDGPIMSDSAASAEQVIRGLERAFEADDAAGVVLRINSPGGSAVHARQIYQEIR
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
RLREEYEDIPVHAVIEDIGTSGAYYVAAAADQIHVNESSIVGSIGVIMGSFGIGEALEKL
HHHHHHHCCCHHHHHHHHCCCCCEEEEEECCEEECCHHHHHHHHHHHHHCCCHHHHHHHH
GIERRVYTAGDDKAFLDPFAPEDEAHVEHVRTMLDDIHGQFIAAVRDGRGEQIDAAGADE
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCH
DRLFSGLIWTGQQSLDKGLADEIGSVRSVARDVIGEEELVDYTARRDFLSQLAERFGTAV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GQGVYQSLETFEHQPR
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEETSERDALLELLKENIREQRRARRWRLITRGAILVVVVLVAVSLGRLDFAADEEIGP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HTAEVRIDGPIMSDSAASAEQVIRGLERAFEADDAAGVVLRINSPGGSAVHARQIYQEIR
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
RLREEYEDIPVHAVIEDIGTSGAYYVAAAADQIHVNESSIVGSIGVIMGSFGIGEALEKL
HHHHHHHCCCHHHHHHHHCCCCCEEEEEECCEEECCHHHHHHHHHHHHHCCCHHHHHHHH
GIERRVYTAGDDKAFLDPFAPEDEAHVEHVRTMLDDIHGQFIAAVRDGRGEQIDAAGADE
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCH
DRLFSGLIWTGQQSLDKGLADEIGSVRSVARDVIGEEELVDYTARRDFLSQLAERFGTAV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GQGVYQSLETFEHQPR
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA