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The map label for this gene is fabH [H]

Identifier: 121998025

GI number: 121998025

Start: 1341301

End: 1342272

Strand: Reverse

Name: fabH [H]

Synonym: Hhal_1235

Alternate gene names: 121998025

Gene position: 1342272-1341301 (Counterclockwise)

Preceding gene: 121998026

Following gene: 121998024

Centisome position: 50.11

GC content: 65.64

Gene sequence:

>972_bases
GTGAGGAACGCAAGGATTATCGGCACGGGGAGCTATCTTCCCGAACGGGTGGTCACCAATCAAGATCTCGAGCAGCACGT
CGAGACCTCCGATCAGTGGATCCGTGAGCGTACCGGGATCTGTGAGCGGCGGGTGATCGGCGAGGACGAGGTCTGTGGAG
ACCTCGGCCGGATTGCCGCACAACGCGCCCTGGAGGCTGCCGGGGTCAGCGGGGACGAGATCGATCTGATCATCGTCGCG
ACGTGCACCCCTGACCGCATCTTCCCCAGTACGGCCTCGTCGCTCCAGCGCGCCCTGGGGGTTCGTCCGGGGGCGGCGGC
GTTTGATATCGCCGCAGCGTGCTCCGGCTTTATCTACGCCCTGGGGATTGCTGAGCGTTTTGTGCGCTTCGGCGACGCCC
AGCGTGCCCTGGTCGTCGGTGCGGAGGCGATGACCCGAATCCTCAATTGGGACGATCGGGGGACCTGTGTGCTCTTCGGG
GACGGCGGCGGCGCCGTGGTCCTGGAGGCTTCTGAGGAGCCCGGGGTGCTCTCCACCCACCTGCATTGCGACGGGCGTTA
CGAGCCCTTGCTGTACGTGCCATGGGGGCCGGGGCGTGGTTATGCCGCGCTGGGGGCCGAGAGCGGCTATATCCACATGC
GAGGGAACGAGGTGTTCAAGGTGGCTGTGAACACCTTGACGCGGATCGTCGAAGAGACCCTGGATGCCGCCGGTGTCGAT
AAAGGGGAGGTCGACTGGCTGGTCCCGCACCAGGCGAATATCCGCATCATCCAGGCCACTGCCAAGAAGCTCGACCTCCC
GATGGAGCGCGTCGTCGTGACGGTGGGTGAGCACGGCAACACGTCGGCAGCCTCGATCCCGATTGCCCTCGATACCGCAG
TGCGCGACGGTCGCATCCAGCGCGGTGAGACCCTGCTGCTGGAGGCCTTCGGCGGCGGATTCACCTGGGGATCGGCGCTG
GTGCGCTATTAA

Upstream 100 bases:

>100_bases
TCGGCCGGGCCATTGACACCGCGGTTCGCGAGGCCGAGCAAGGAGTCCCGGATTTGATCAATGCGCGTATCGAGCGGCTG
CTGGGGGCGAAGGAAGGGGC

Downstream 100 bases:

>100_bases
ACAGCCCGCCCTGAATCAAGATTCCGTGCAGGAGCAGAGATGAGCAAGCAAACCCCGGAACTTGCGATGGCCTTTCCCGG
CCAGGGTTCCCAGGCGGTCG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRNARIIGTGSYLPERVVTNQDLEQHVETSDQWIRERTGICERRVIGEDEVCGDLGRIAAQRALEAAGVSGDEIDLIIVA
TCTPDRIFPSTASSLQRALGVRPGAAAFDIAAACSGFIYALGIAERFVRFGDAQRALVVGAEAMTRILNWDDRGTCVLFG
DGGGAVVLEASEEPGVLSTHLHCDGRYEPLLYVPWGPGRGYAALGAESGYIHMRGNEVFKVAVNTLTRIVEETLDAAGVD
KGEVDWLVPHQANIRIIQATAKKLDLPMERVVVTVGEHGNTSAASIPIALDTAVRDGRIQRGETLLLEAFGGGFTWGSAL
VRY

Sequences:

>Translated_323_residues
MRNARIIGTGSYLPERVVTNQDLEQHVETSDQWIRERTGICERRVIGEDEVCGDLGRIAAQRALEAAGVSGDEIDLIIVA
TCTPDRIFPSTASSLQRALGVRPGAAAFDIAAACSGFIYALGIAERFVRFGDAQRALVVGAEAMTRILNWDDRGTCVLFG
DGGGAVVLEASEEPGVLSTHLHCDGRYEPLLYVPWGPGRGYAALGAESGYIHMRGNEVFKVAVNTLTRIVEETLDAAGVD
KGEVDWLVPHQANIRIIQATAKKLDLPMERVVVTVGEHGNTSAASIPIALDTAVRDGRIQRGETLLLEAFGGGFTWGSAL
VRY
>Mature_323_residues
MRNARIIGTGSYLPERVVTNQDLEQHVETSDQWIRERTGICERRVIGEDEVCGDLGRIAAQRALEAAGVSGDEIDLIIVA
TCTPDRIFPSTASSLQRALGVRPGAAAFDIAAACSGFIYALGIAERFVRFGDAQRALVVGAEAMTRILNWDDRGTCVLFG
DGGGAVVLEASEEPGVLSTHLHCDGRYEPLLYVPWGPGRGYAALGAESGYIHMRGNEVFKVAVNTLTRIVEETLDAAGVD
KGEVDWLVPHQANIRIIQATAKKLDLPMERVVVTVGEHGNTSAASIPIALDTAVRDGRIQRGETLLLEAFGGGFTWGSAL
VRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=319, Percent_Identity=56.7398119122257, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34703; Mature: 34703

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00064 L_LDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNARIIGTGSYLPERVVTNQDLEQHVETSDQWIRERTGICERRVIGEDEVCGDLGRIAA
CCCCEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
QRALEAAGVSGDEIDLIIVATCTPDRIFPSTASSLQRALGVRPGAAAFDIAAACSGFIYA
HHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LGIAERFVRFGDAQRALVVGAEAMTRILNWDDRGTCVLFGDGGGAVVLEASEEPGVLSTH
HHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEE
LHCDGRYEPLLYVPWGPGRGYAALGAESGYIHMRGNEVFKVAVNTLTRIVEETLDAAGVD
EEECCCCCCEEEEECCCCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCC
KGEVDWLVPHQANIRIIQATAKKLDLPMERVVVTVGEHGNTSAASIPIALDTAVRDGRIQ
CCCEEEECCCCCCEEEEEEEHHHHCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCCCCC
RGETLLLEAFGGGFTWGSALVRY
CCCEEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MRNARIIGTGSYLPERVVTNQDLEQHVETSDQWIRERTGICERRVIGEDEVCGDLGRIAA
CCCCEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
QRALEAAGVSGDEIDLIIVATCTPDRIFPSTASSLQRALGVRPGAAAFDIAAACSGFIYA
HHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LGIAERFVRFGDAQRALVVGAEAMTRILNWDDRGTCVLFGDGGGAVVLEASEEPGVLSTH
HHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEE
LHCDGRYEPLLYVPWGPGRGYAALGAESGYIHMRGNEVFKVAVNTLTRIVEETLDAAGVD
EEECCCCCCEEEEECCCCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCC
KGEVDWLVPHQANIRIIQATAKKLDLPMERVVVTVGEHGNTSAASIPIALDTAVRDGRIQ
CCCEEEECCCCCCEEEEEEEHHHHCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCCCCC
RGETLLLEAFGGGFTWGSALVRY
CCCEEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA