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The map label for this gene is fabD [H]

Identifier: 121998024

GI number: 121998024

Start: 1340308

End: 1341261

Strand: Reverse

Name: fabD [H]

Synonym: Hhal_1234

Alternate gene names: 121998024

Gene position: 1341261-1340308 (Counterclockwise)

Preceding gene: 121998025

Following gene: 121998023

Centisome position: 50.08

GC content: 67.71

Gene sequence:

>954_bases
ATGAGCAAGCAAACCCCGGAACTTGCGATGGCCTTTCCCGGCCAGGGTTCCCAGGCGGTCGGGATGATGGCGCCGTGGCA
AGATCACGATACTGTGCGCGCGACTTTTCGCGAGGCCTCCGAGGCCCTGGGGTACGACCTCTGGGACCTCGTCGCCAATG
GTCCCAGCGAAGAGCTCGATCGTACGGATCGCACCCAGCCGGCCATCCTGGTGGCCAGTGTGGCGCTGTGGCGTGTCTGG
CAGGAGCGCGACGGCGCAGAGCCGGCGGTGCTGGCCGGGCATAGCCTGGGTGAATACAGCGCCCTGGTCGCCGCCGAGGC
GCTGCAGCTGGGTGACGCCGCGGCACTGGTGGCTGAACGTGGCCGCTACATGCAAGAGGCCGTGCCGGCCGGCGAGGGCG
CCATGGCGGCGATCATCGGCCTGGACGACGACCGGATTCGCGAGATCTGCGCAACCGCCGCCCAGGGTGCCGTGGTGCAG
CCCGTGAACTTCAATGCTCCGGGACAGGTGGTCATTGCGGGGAACCATGAGGCCGTTGAGCGGGCCGGTTCCGCTGCGAA
GGAGGCGGGCGCCAAGCGCGTTCTGCCGCTACCGGTGAGCGTACCGTCCCACTGTAGCCTGATGCACCCGGCCGCTGAGC
GCCTGGCGCAGCGCCTGGAAGAGGTGGTCATCAACGAGCCGCGCCGGCCGGTCATTCACAATGTCGATGTCTCGGTGAGC
CGGGATGTCGCCTCCATTCGCCGCCGACTGGTCGAGCAGCTTGCCAGTCCCGTGCGCTGGACGGAGACGGTACAGAAGAT
GAGCGCCGATGGCGTCCAGGTCGTCGCTGAGTGTGGGCCTGGCAAGGTCCTGACCGGATTGACGCGGCGCATTGACCGCA
GCCTTCAGGGGGGCACGCTTAGCGAGCCCGAGGCCTTTGACGACATGCTGCGCCGTTTCTCGGCGAGCAGCTAA

Upstream 100 bases:

>100_bases
CCTGCTGCTGGAGGCCTTCGGCGGCGGATTCACCTGGGGATCGGCGCTGGTGCGCTATTAAACAGCCCGCCCTGAATCAA
GATTCCGTGCAGGAGCAGAG

Downstream 100 bases:

>100_bases
TCCCACCCGGACAGTTTCAAGGAGGCAGCGTGCACGGCAAAGACGACCTGCAGGGCCAGATCGCTCTGGTAACCGGGGCG
AGCCGGGGCATCGGCCGCGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSKQTPELAMAFPGQGSQAVGMMAPWQDHDTVRATFREASEALGYDLWDLVANGPSEELDRTDRTQPAILVASVALWRVW
QERDGAEPAVLAGHSLGEYSALVAAEALQLGDAAALVAERGRYMQEAVPAGEGAMAAIIGLDDDRIREICATAAQGAVVQ
PVNFNAPGQVVIAGNHEAVERAGSAAKEAGAKRVLPLPVSVPSHCSLMHPAAERLAQRLEEVVINEPRRPVIHNVDVSVS
RDVASIRRRLVEQLASPVRWTETVQKMSADGVQVVAECGPGKVLTGLTRRIDRSLQGGTLSEPEAFDDMLRRFSASS

Sequences:

>Translated_317_residues
MSKQTPELAMAFPGQGSQAVGMMAPWQDHDTVRATFREASEALGYDLWDLVANGPSEELDRTDRTQPAILVASVALWRVW
QERDGAEPAVLAGHSLGEYSALVAAEALQLGDAAALVAERGRYMQEAVPAGEGAMAAIIGLDDDRIREICATAAQGAVVQ
PVNFNAPGQVVIAGNHEAVERAGSAAKEAGAKRVLPLPVSVPSHCSLMHPAAERLAQRLEEVVINEPRRPVIHNVDVSVS
RDVASIRRRLVEQLASPVRWTETVQKMSADGVQVVAECGPGKVLTGLTRRIDRSLQGGTLSEPEAFDDMLRRFSASS
>Mature_316_residues
SKQTPELAMAFPGQGSQAVGMMAPWQDHDTVRATFREASEALGYDLWDLVANGPSEELDRTDRTQPAILVASVALWRVWQ
ERDGAEPAVLAGHSLGEYSALVAAEALQLGDAAALVAERGRYMQEAVPAGEGAMAAIIGLDDDRIREICATAAQGAVVQP
VNFNAPGQVVIAGNHEAVERAGSAAKEAGAKRVLPLPVSVPSHCSLMHPAAERLAQRLEEVVINEPRRPVIHNVDVSVSR
DVASIRRRLVEQLASPVRWTETVQKMSADGVQVVAECGPGKVLTGLTRRIDRSLQGGTLSEPEAFDDMLRRFSASS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=33.8870431893688, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI27477045, Length=116, Percent_Identity=40.5172413793103, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1787334, Length=301, Percent_Identity=59.8006644518272, Blast_Score=337, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI71984332, Length=271, Percent_Identity=29.8892988929889, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=26, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=36.241610738255, Blast_Score=148, Evalue=5e-36,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33924; Mature: 33793

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQTPELAMAFPGQGSQAVGMMAPWQDHDTVRATFREASEALGYDLWDLVANGPSEELD
CCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
RTDRTQPAILVASVALWRVWQERDGAEPAVLAGHSLGEYSALVAAEALQLGDAAALVAER
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHH
GRYMQEAVPAGEGAMAAIIGLDDDRIREICATAAQGAVVQPVNFNAPGQVVIAGNHEAVE
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCHHHHH
RAGSAAKEAGAKRVLPLPVSVPSHCSLMHPAAERLAQRLEEVVINEPRRPVIHNVDVSVS
HHHHHHHHCCCCCEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCHHH
RDVASIRRRLVEQLASPVRWTETVQKMSADGVQVVAECGPGKVLTGLTRRIDRSLQGGTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
SEPEAFDDMLRRFSASS
CCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKQTPELAMAFPGQGSQAVGMMAPWQDHDTVRATFREASEALGYDLWDLVANGPSEELD
CCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
RTDRTQPAILVASVALWRVWQERDGAEPAVLAGHSLGEYSALVAAEALQLGDAAALVAER
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHH
GRYMQEAVPAGEGAMAAIIGLDDDRIREICATAAQGAVVQPVNFNAPGQVVIAGNHEAVE
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCHHHHH
RAGSAAKEAGAKRVLPLPVSVPSHCSLMHPAAERLAQRLEEVVINEPRRPVIHNVDVSVS
HHHHHHHHCCCCCEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCHHH
RDVASIRRRLVEQLASPVRWTETVQKMSADGVQVVAECGPGKVLTGLTRRIDRSLQGGTL
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
SEPEAFDDMLRRFSASS
CCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]