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The map label for this gene is luxQ [H]

Identifier: 121997915

GI number: 121997915

Start: 1220280

End: 1221788

Strand: Reverse

Name: luxQ [H]

Synonym: Hhal_1124

Alternate gene names: 121997915

Gene position: 1221788-1220280 (Counterclockwise)

Preceding gene: 121997925

Following gene: 121997914

Centisome position: 45.62

GC content: 68.32

Gene sequence:

>1509_bases
GTGGGGCTGGGTGCCTGGCGGATCGGCCTCGCCACCGAGTGTATCGAGCTTTGTCCGCGCGCCCGGGCCCTCTTTGGCCT
GGAGGATCCAACCCCGCGTCCGGCCAGCGAGGGGCTGGCCTGCTACGTCTCCGAGCACCGTCAGCAGCTGCAGGACGCCT
ATCGCCAGTGCATCGACTACGGCACTGCCTACGACGTCGAATTCCAGGCCCTGACCGCCGGGGGTGGGCGGCGCTGGCTA
CGGGCGACTGGAACCCCGGTGTATGACGCCGCCGGGCAGATCACCGCGGTGGCCGGCGCCCTGCTCGATATCGACGACTA
CAAGGCGCGCGAGGCAGAACTTGCCGAGGCGCGGGTGGCCGCCGAGCGGACCGACCGGGCCAAGTCCGAGTTCCTCTCGG
CGATGAGCCACGAGCTGCGCACCCCCCTGAACGCCATTGTCGGTTTTGCGCAGCTGATCTACGCCGACGAGGAGCTGGAT
ACACGGACCCGCAACGAGTACCTGCGCCATATCCTCAGTGCCGGCTGGCACCTGCGTGATCTGGTCGGCGACATCCTGGA
CCTGGCACGGATCGAGGCCGGCAGGGCTTCGCTGGCGCCGGAAACCGTGCGCATCCCTGATCTGTTGCAGGATTGCCTGC
GCCTGGTGCGGGATCAGGCCGCCGAGTACAGCGTCAGCCTGCGCCTGGAAGAGCCCGAGCATCCCGTAGGTGTGTGCGTC
TGGGCGGACCGGCTGCGGCTCAAGCAGGTGGTGCTGAACCTGCTGACCAACGCCATCAAGTACAACCGTGAGGGCGGCTC
GGTGGTCCTTAGCTACGGGCGCGACGCCGCCGGGCAGGTCTGGGTCGACGTGGTGGATAGCGGGCTGGGGATCGACCCGC
AGTGCCGCGCCGGCCTGTTCGAGACCTTCGACCGCCTGGGGCGCGAGACGGGCAGCATCGAGGGTGTAGGAATCGGGTTG
CCGCTGGCTCTGCGGCTCAGTCGCCTGATGGGCGGTGAGTTGCAACTGGTCGATAGCGTGCCGGATCAGGGGTCGCGTTT
TCGCCTGACGCTGCCGGGGATCGATGCCGAGGGCTGGGATCGGCATCATACGCCCAGCCTCGACCCACGGTTGATGGAGG
AGCGCGCCGACGACCCGCCGCTGCGCCTGCTGGCGGTGGAGGACAACCGGGTGAACATGCTGCTGCTCAGCGGTCTGGTG
GCCAAGCGTCAGGGCGTGGAGCTGTTCGAGGCGTTCGATGGACGCACGGGCCTGGAACTGGCGCAGCGGGTCCAGCCGGA
TCTGATCCTGCTCGACATGCACCTGCCCGACACTGACGGCTTCGCCCTGGCCCGGCAGCTGCGCGCCATTTCGGAGCTCG
AGGCGGTGCCGCTGGTGGCGGTCAGCGCCGACGCCAGCGATGAAGTGCGCCGCAGGGCCCTGGACGAGGGGTTCAACGAG
TACATCGTCAAGCCCTTCGAGCTGGAGCAGCTCGATGCGCTGATCCGGGAGGTCCGGTTGAGTCGCTAG

Upstream 100 bases:

>100_bases
GCTGTGTACCGCTCGTTGCCGCGCTGTTGAGGGTGAACATTTGCCCAGTTCGAACCACGAGTCCGATCCGGACGACTTAA
TCACCCGGGCCGCCGCGTCC

Downstream 100 bases:

>100_bases
CCGGAGGGCCGCGGTGCAGGAGGACGCCACCACCTACTGCCTGACACTGTTCGTGACGGAAGCGATGCGGGTCGCGGTCG
GGCGGCTCGGCGTGGTGGCG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MGLGAWRIGLATECIELCPRARALFGLEDPTPRPASEGLACYVSEHRQQLQDAYRQCIDYGTAYDVEFQALTAGGGRRWL
RATGTPVYDAAGQITAVAGALLDIDDYKAREAELAEARVAAERTDRAKSEFLSAMSHELRTPLNAIVGFAQLIYADEELD
TRTRNEYLRHILSAGWHLRDLVGDILDLARIEAGRASLAPETVRIPDLLQDCLRLVRDQAAEYSVSLRLEEPEHPVGVCV
WADRLRLKQVVLNLLTNAIKYNREGGSVVLSYGRDAAGQVWVDVVDSGLGIDPQCRAGLFETFDRLGRETGSIEGVGIGL
PLALRLSRLMGGELQLVDSVPDQGSRFRLTLPGIDAEGWDRHHTPSLDPRLMEERADDPPLRLLAVEDNRVNMLLLSGLV
AKRQGVELFEAFDGRTGLELAQRVQPDLILLDMHLPDTDGFALARQLRAISELEAVPLVAVSADASDEVRRRALDEGFNE
YIVKPFELEQLDALIREVRLSR

Sequences:

>Translated_502_residues
MGLGAWRIGLATECIELCPRARALFGLEDPTPRPASEGLACYVSEHRQQLQDAYRQCIDYGTAYDVEFQALTAGGGRRWL
RATGTPVYDAAGQITAVAGALLDIDDYKAREAELAEARVAAERTDRAKSEFLSAMSHELRTPLNAIVGFAQLIYADEELD
TRTRNEYLRHILSAGWHLRDLVGDILDLARIEAGRASLAPETVRIPDLLQDCLRLVRDQAAEYSVSLRLEEPEHPVGVCV
WADRLRLKQVVLNLLTNAIKYNREGGSVVLSYGRDAAGQVWVDVVDSGLGIDPQCRAGLFETFDRLGRETGSIEGVGIGL
PLALRLSRLMGGELQLVDSVPDQGSRFRLTLPGIDAEGWDRHHTPSLDPRLMEERADDPPLRLLAVEDNRVNMLLLSGLV
AKRQGVELFEAFDGRTGLELAQRVQPDLILLDMHLPDTDGFALARQLRAISELEAVPLVAVSADASDEVRRRALDEGFNE
YIVKPFELEQLDALIREVRLSR
>Mature_501_residues
GLGAWRIGLATECIELCPRARALFGLEDPTPRPASEGLACYVSEHRQQLQDAYRQCIDYGTAYDVEFQALTAGGGRRWLR
ATGTPVYDAAGQITAVAGALLDIDDYKAREAELAEARVAAERTDRAKSEFLSAMSHELRTPLNAIVGFAQLIYADEELDT
RTRNEYLRHILSAGWHLRDLVGDILDLARIEAGRASLAPETVRIPDLLQDCLRLVRDQAAEYSVSLRLEEPEHPVGVCVW
ADRLRLKQVVLNLLTNAIKYNREGGSVVLSYGRDAAGQVWVDVVDSGLGIDPQCRAGLFETFDRLGRETGSIEGVGIGLP
LALRLSRLMGGELQLVDSVPDQGSRFRLTLPGIDAEGWDRHHTPSLDPRLMEERADDPPLRLLAVEDNRVNMLLLSGLVA
KRQGVELFEAFDGRTGLELAQRVQPDLILLDMHLPDTDGFALARQLRAISELEAVPLVAVSADASDEVRRRALDEGFNEY
IVKPFELEQLDALIREVRLSR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=474, Percent_Identity=29.1139240506329, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=34.9875930521092, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788713, Length=431, Percent_Identity=29.6983758700696, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=31.5018315018315, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=31.4176245210728, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=29.2490118577075, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788549, Length=281, Percent_Identity=26.3345195729537, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=29.6943231441048, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=29.7777777777778, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=27.8969957081545, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=35.8974358974359, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=33.0434782608696, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786911, Length=92, Percent_Identity=41.304347826087, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55604; Mature: 55473

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGAWRIGLATECIELCPRARALFGLEDPTPRPASEGLACYVSEHRQQLQDAYRQCIDY
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GTAYDVEFQALTAGGGRRWLRATGTPVYDAAGQITAVAGALLDIDDYKAREAELAEARVA
CCEECEEEEEEECCCCCEEEEECCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AERTDRAKSEFLSAMSHELRTPLNAIVGFAQLIYADEELDTRTRNEYLRHILSAGWHLRD
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
LVGDILDLARIEAGRASLAPETVRIPDLLQDCLRLVRDQAAEYSVSLRLEEPEHPVGVCV
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEEEE
WADRLRLKQVVLNLLTNAIKYNREGGSVVLSYGRDAAGQVWVDVVDSGLGIDPQCRAGLF
EHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
ETFDRLGRETGSIEGVGIGLPLALRLSRLMGGELQLVDSVPDQGSRFRLTLPGIDAEGWD
HHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCC
RHHTPSLDPRLMEERADDPPLRLLAVEDNRVNMLLLSGLVAKRQGVELFEAFDGRTGLEL
CCCCCCCCHHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHCCCCHHHH
AQRVQPDLILLDMHLPDTDGFALARQLRAISELEAVPLVAVSADASDEVRRRALDEGFNE
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCHH
YIVKPFELEQLDALIREVRLSR
HCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLGAWRIGLATECIELCPRARALFGLEDPTPRPASEGLACYVSEHRQQLQDAYRQCIDY
CCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GTAYDVEFQALTAGGGRRWLRATGTPVYDAAGQITAVAGALLDIDDYKAREAELAEARVA
CCEECEEEEEEECCCCCEEEEECCCCHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AERTDRAKSEFLSAMSHELRTPLNAIVGFAQLIYADEELDTRTRNEYLRHILSAGWHLRD
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
LVGDILDLARIEAGRASLAPETVRIPDLLQDCLRLVRDQAAEYSVSLRLEEPEHPVGVCV
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEEEE
WADRLRLKQVVLNLLTNAIKYNREGGSVVLSYGRDAAGQVWVDVVDSGLGIDPQCRAGLF
EHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
ETFDRLGRETGSIEGVGIGLPLALRLSRLMGGELQLVDSVPDQGSRFRLTLPGIDAEGWD
HHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCC
RHHTPSLDPRLMEERADDPPLRLLAVEDNRVNMLLLSGLVAKRQGVELFEAFDGRTGLEL
CCCCCCCCHHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHCCCCHHHH
AQRVQPDLILLDMHLPDTDGFALARQLRAISELEAVPLVAVSADASDEVRRRALDEGFNE
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCHH
YIVKPFELEQLDALIREVRLSR
HCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA