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The map label for this gene is yggW [H]

Identifier: 121997762

GI number: 121997762

Start: 1043301

End: 1044527

Strand: Reverse

Name: yggW [H]

Synonym: Hhal_0971

Alternate gene names: 121997762

Gene position: 1044527-1043301 (Counterclockwise)

Preceding gene: 121997763

Following gene: 121997761

Centisome position: 39.0

GC content: 73.43

Gene sequence:

>1227_bases
ATGAGCCTCGGCGCCGGGGCGCAGCTGCCGCCGCTGGCGGTCTATATCCATCTGCCCTGGTGTCTGCAGCGCTGCGGCTA
CTGCGACTTCAACGCCCACGCCCTGCGCGGAGAGCTCCCCGCCCGGGCCTACGTGGACGCCCTGGGGCGCGAGCTGCGCC
GCCAGGCCCCGGCGGCGCTCGGGCGCCGCGTGACTAGCGTCTTCATCGGGGGCGGCACACCGAGTCTCTTCCCGCCCGGT
CCGATCGGCGAGCTGCTCGACACCCTGGACGCGGTGCTGGGCCTGGAGTCGGGGGCAGAGATCACCCTGGAGGCCAACCC
AGGCGCCAGCGAGAACGCGCGGCTGCGGGGGTTCCGGCAGGCCGGGGTGACCCGTCTGTCCCTGGGGGTGCAGAGCCTGG
ACGACACGCTGCTGGCCCGCCTGGGGCGGATCCACGACGCCGTCGCCGCGCGCGAGGCCGTGGCTGAGGCGTATGCCGTC
GGGTTCCGCGGTATCAACGCCGACGTCATGTACGGCCTGCCCGGGCAGGGGGTCACCGGGGCCGAGGCCGACGTGGCCGG
AGTCATCGCGCTGGGGGCCGACCACGTCAGCCATTATCAGCTGACCATCGAGCCGGAGACGCCCTTTGGGCGCCGCCCAC
CTCCGGGTCTGCCCGACGAGGAGACGGTGCTGGAGATGGAGGCGGTGTGCCGGCAGCGGCTGGCGCAGGCCGGTCTGGAG
CGTTACGAGGTCTCGGCCTTCGCCCGCCCCGGGCAGCGCAGCGTCCACAATCTCGGTTACTGGACCTTCGGCGACTACCT
GGGCCTGGGCGCCGGGGCGGCCGGCAAGCGGACCGGCGCCGACGGCCGGGTGCTGCGCACCCGCCAGCGCCGCTCGCCGC
GGGCCTGGATGGCCGCCGTCGGCAGCGCCCGGGTCGAGGCTGAGTGTATTGAGCTGACACCGTCGGAGCAGGCCTTTGAG
GTCCTGCTCAACGGGCTGCGCCTGCGTGAGGGGCTTCCGGAACGACTGGCGGTGGCGCGCAGTGGCTGCAGCCTGCCGGC
ATTGCGCGACTGGCTGGCGCCCCTGTGTGCCGGCGGCTGGCTGGAGTGGCGTGGCGGGCGGATTCGGGCCAGCGCCGCCG
GCTACGAGATGCTCGATACCCTGCTGCTCGAGCTGCTCCCCGGCCCGCCGGATCCGGGTTCCGGGGGCAGTGCACCTTCC
TCGCACGGCGGCAACGCGCTAAAATAA

Upstream 100 bases:

>100_bases
GATGCGCCCGCTAAGGACGCACGCAGCCACCGCGGGCAGGCGCTGCGCGCGCTGATTCAGGGGATCGCCGCCGAGGTGGC
CGGGTGACCCGGCGGCGCCC

Downstream 100 bases:

>100_bases
CATGTCAAACTGCTGAATTGTGTCTGGAGGAGCGCGATGGCTCGCGTCACCGTAGAAGATTGCCTGGACAACGTAGACAA
CCGCTTCGAGCTCGTGCTCG

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLGAGAQLPPLAVYIHLPWCLQRCGYCDFNAHALRGELPARAYVDALGRELRRQAPAALGRRVTSVFIGGGTPSLFPPG
PIGELLDTLDAVLGLESGAEITLEANPGASENARLRGFRQAGVTRLSLGVQSLDDTLLARLGRIHDAVAAREAVAEAYAV
GFRGINADVMYGLPGQGVTGAEADVAGVIALGADHVSHYQLTIEPETPFGRRPPPGLPDEETVLEMEAVCRQRLAQAGLE
RYEVSAFARPGQRSVHNLGYWTFGDYLGLGAGAAGKRTGADGRVLRTRQRRSPRAWMAAVGSARVEAECIELTPSEQAFE
VLLNGLRLREGLPERLAVARSGCSLPALRDWLAPLCAGGWLEWRGGRIRASAAGYEMLDTLLLELLPGPPDPGSGGSAPS
SHGGNALK

Sequences:

>Translated_408_residues
MSLGAGAQLPPLAVYIHLPWCLQRCGYCDFNAHALRGELPARAYVDALGRELRRQAPAALGRRVTSVFIGGGTPSLFPPG
PIGELLDTLDAVLGLESGAEITLEANPGASENARLRGFRQAGVTRLSLGVQSLDDTLLARLGRIHDAVAAREAVAEAYAV
GFRGINADVMYGLPGQGVTGAEADVAGVIALGADHVSHYQLTIEPETPFGRRPPPGLPDEETVLEMEAVCRQRLAQAGLE
RYEVSAFARPGQRSVHNLGYWTFGDYLGLGAGAAGKRTGADGRVLRTRQRRSPRAWMAAVGSARVEAECIELTPSEQAFE
VLLNGLRLREGLPERLAVARSGCSLPALRDWLAPLCAGGWLEWRGGRIRASAAGYEMLDTLLLELLPGPPDPGSGGSAPS
SHGGNALK
>Mature_407_residues
SLGAGAQLPPLAVYIHLPWCLQRCGYCDFNAHALRGELPARAYVDALGRELRRQAPAALGRRVTSVFIGGGTPSLFPPGP
IGELLDTLDAVLGLESGAEITLEANPGASENARLRGFRQAGVTRLSLGVQSLDDTLLARLGRIHDAVAAREAVAEAYAVG
FRGINADVMYGLPGQGVTGAEADVAGVIALGADHVSHYQLTIEPETPFGRRPPPGLPDEETVLEMEAVCRQRLAQAGLER
YEVSAFARPGQRSVHNLGYWTFGDYLGLGAGAAGKRTGADGRVLRTRQRRSPRAWMAAVGSARVEAECIELTPSEQAFEV
LLNGLRLREGLPERLAVARSGCSLPALRDWLAPLCAGGWLEWRGGRIRASAAGYEMLDTLLLELLPGPPDPGSGGSAPSS
HGGNALK

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=298, Percent_Identity=40.2684563758389, Blast_Score=182, Evalue=7e-46,
Organism=Escherichia coli, GI1789325, Length=376, Percent_Identity=43.3510638297872, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI87082341, Length=287, Percent_Identity=30.6620209059233, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 43174; Mature: 43042

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGAGAQLPPLAVYIHLPWCLQRCGYCDFNAHALRGELPARAYVDALGRELRRQAPAAL
CCCCCCCCCCCEEEEEECHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GRRVTSVFIGGGTPSLFPPGPIGELLDTLDAVLGLESGAEITLEANPGASENARLRGFRQ
HHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
AGVTRLSLGVQSLDDTLLARLGRIHDAVAAREAVAEAYAVGFRGINADVMYGLPGQGVTG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
AEADVAGVIALGADHVSHYQLTIEPETPFGRRPPPGLPDEETVLEMEAVCRQRLAQAGLE
CCCCHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RYEVSAFARPGQRSVHNLGYWTFGDYLGLGAGAAGKRTGADGRVLRTRQRRSPRAWMAAV
HHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
GSARVEAECIELTPSEQAFEVLLNGLRLREGLPERLAVARSGCSLPALRDWLAPLCAGGW
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
LEWRGGRIRASAAGYEMLDTLLLELLPGPPDPGSGGSAPSSHGGNALK
EEECCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLGAGAQLPPLAVYIHLPWCLQRCGYCDFNAHALRGELPARAYVDALGRELRRQAPAAL
CCCCCCCCCCEEEEEECHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHH
GRRVTSVFIGGGTPSLFPPGPIGELLDTLDAVLGLESGAEITLEANPGASENARLRGFRQ
HHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
AGVTRLSLGVQSLDDTLLARLGRIHDAVAAREAVAEAYAVGFRGINADVMYGLPGQGVTG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
AEADVAGVIALGADHVSHYQLTIEPETPFGRRPPPGLPDEETVLEMEAVCRQRLAQAGLE
CCCCHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RYEVSAFARPGQRSVHNLGYWTFGDYLGLGAGAAGKRTGADGRVLRTRQRRSPRAWMAAV
HHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
GSARVEAECIELTPSEQAFEVLLNGLRLREGLPERLAVARSGCSLPALRDWLAPLCAGGW
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
LEWRGGRIRASAAGYEMLDTLLLELLPGPPDPGSGGSAPSSHGGNALK
EEECCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]