Click here to switch to the map view.

The map label for this gene is cheA [H]

Identifier: 121997725

GI number: 121997725

Start: 1011000

End: 1013504

Strand: Reverse

Name: cheA [H]

Synonym: Hhal_0934

Alternate gene names: 121997725

Gene position: 1013504-1011000 (Counterclockwise)

Preceding gene: 121997735

Following gene: 121997722

Centisome position: 37.84

GC content: 75.85

Gene sequence:

>2505_bases
ATGGATGAGCGACGAACCAAGGCCTTCGGCGTCGACCCCCGGCGCGAGCTGACCCGGCTGCTGCCCGAACTGCGCGACAG
CGTCAGCGCCGCGGCGGTGCGTCTGCAGGAGGCGGGTGACGAGCCCGGCGCCCTGACCGCGCTCCACGGCGAGCTCCAGC
GCCTGCACGGCGGTTTCCTGTTCGTCGGCGTACGCGAACTCGAGCACCTCAGTGCCGAGCTGCGCGGCGCCGCGGCCGAC
CTGGAACGGGCCTACCAGTCGCCGGACGAGGGCGGGGTGGAGGTCCAGCCGCTGCGCGCGGCCCTGATGGATGCCGTGCT
GCGGCTGCCCCGGGCCATCGAGCGCATCGCCGTACGGGCCGAGGACCCGGTGGCGGAGCTGGCCAGCCTCATCGACGGGC
TGCGCCGCGCCCGCGGTCAGCCGCGCTACGACAGCCTGGCGCTGCTGCGTCAGTGCGTTGACCCGAGCGCGCCCGCGGCC
CACGGCGAGGTCGCCGAGACCGCCCGCACCAGCCGTCTGGCCTACCAGCGCGGGCTCCTGGAGCTGATCCGCGGCGACGA
ACGCCGGGCCCTCGGCCAGCTGCGCGGCGTCCTCGAGCCCCTGGAGGCGGCCCTGGGCGACAGCGCCGCCGGCAGCGCCT
GCTGGAGCGCCCTGGCGGTGCTCGATCTGCTGGAGCAGGGCGAGACCCTGGATCCGGGGCAGAAGCGGGCGATTGCCGCC
TACGACCGCGAGCTGCGCCGGCTGCTCGAGCACGGTGCAGTGGGCGGGCTCCCCGAATCGAGCATGGCCGAGGCGCTGCT
CCAGCCGCTCACCGAGGCGCCGGGCACCGGCCGGGTGGGCCAGGTCCAGGCGGCCGCCCGGCGCTTGCCCGGGGCCACCC
TGGCCATGCCGCCCCCGGCCGAGGATGAGGCCGGGGCGGCCTCGCGGGCGCTGGTGCGCAGCGACGTCGATCTGCAGGCG
CTGTTCTACGCCGAGGTGGGGCCGGCGCTGTCGCAGATCGGCGCCGCCCTGCAGCGCTGGCGCGCCGGCGACCCAGAGGC
GGGGCTGGCCATCCAGCGCATCCTGCACACCCTCAAGGGCGGGGCGCGCTTCGCTGGCCTCACCGAGTTCTTCGCCCACT
GCCACGAACTCGAGGGCGAGGTGGCCACGGCGCTGGCGGATGGCGCTACCGCCGGGACCGCTCAGCGCCTGCGCCACGAA
CTGGAGCAACTGGCCGACCGGGTCGGCGTGCTGCGCCGCGAGGTCCTGGGTCACACCGCGGAGCCGGGCGCCGAGCCGGA
CGCTGAAGCGGCGGCCTTCGATTACGGCGAGCTGTGGGCCGACGAGGACCCGGAGCCGTCCCCTGCGGAGGATGGCTGGG
AGCTGCAGACCGGATCCAGCGCCGAGGTGCTCGGCGACGCCCTGGCCGCCGAATTGGCCGCAACGGAGGACGAGGCCGCC
GACGCGGACGCCGACCCGCCGGATCCCGCCACCGAGTCGGCTCCGGTCGCGGAACCGGCTCGTGACCCCGAGCCGGCGCT
GGCGACCCTGGAGCCGGACATCGACGCCCTCGATCGACAGGTCCACGCCACCGCCGGCGAGTATGGCCGGCGTGTCGAGC
TGGTCGTGGAGGGGGCGTCCCGCGCGCTGCCCGAGGCCTATCTGGAGGCCCTGCGGCCGGCGCTGGAGCACCTGCTGCGC
AACGCCGTGCGCCACGGTATTGAACCCCCCGAGGCGCGCAGTGCCGCCGGTAAGCCGGAGGTCGGCCGAGTTGGGCTCAG
CCTGCGCTACGGCCAGGACGAGGTGCTGCTGGTGGTCAGTGACGACGGCGCCGGACTCGACACCGAGGCGCTGCAGCGCC
AGGTCTCCGACTACGACCCCAACGAGCCCACCGCGGCCCTCAGCGACGATGAGGCGCTGAGCCTGATCTGCCTGCCGGGG
GTCTCCACGCTGGGGCCGGAGGGCGACCCGGGGGCCGGCATGGGCATGGACGAGGTCGCCGGCGTGGTCCACGAACTCGG
TGGCACGCTGGAGATGCAGAGCGCCCCGGGGGCCGGCGCCCGCTTCACCCTGCGGCTGCCCATGCGCGGGGCGAAGGCCG
CGGAGCAGCCCCCCGGCGAGGCCCCCGAGCGGCCTCGCATCCTGGTCCTCGACGACTCGCGCACCATGCGCCGGATCACC
GGTCATCGGCTGGCGCGCCAGGGCTTCGACCCGGAGGGCGCCGCCGGCCTCGACGAGGCGCGGCGCGCCGTGGCCGAGCG
CGCGCCGCGGGCGGTGCTCATCGACCTGGAGATGGAGATGCTCCAGCACGAGGAGGGGCTCGGCGTGCTCCAGCGCCTGG
TGGCCGAGGCCGGGATCGCCGCCGGGGCGGTGGTCGCGGTGAGCACCCGGGCCGTCGATCAGGAGCGGCTCGCGGCCGCG
GGGCTGGGCGCGGCGCGGGTGCTGCTCAAGCCCTACGACGAGGGCCAGCTTGCCGACGCCCTGGCCCAGGCGTGCGCTGC
ACTGGAGGGCGGCGAGCCGGGCTAG

Upstream 100 bases:

>100_bases
CGGGGCTTGATGGCGGCGATGGGGTCCATCACCACGCCGAGTCGGGCGCTCATGGGCAGATTCACGGCAGCTGAGTGGTT
TGTGGCATTGTAACCAACCC

Downstream 100 bases:

>100_bases
AGTTCGCCCAGGGCGAGGCCGACGGCGGCGAGGGCGACCACGGCGGCGGTCTCCGTGCGCAGGACCCGGGGGCCCACCCG
CCCGCGGAGGAAACCGTGTT

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 834; Mature: 834

Protein sequence:

>834_residues
MDERRTKAFGVDPRRELTRLLPELRDSVSAAAVRLQEAGDEPGALTALHGELQRLHGGFLFVGVRELEHLSAELRGAAAD
LERAYQSPDEGGVEVQPLRAALMDAVLRLPRAIERIAVRAEDPVAELASLIDGLRRARGQPRYDSLALLRQCVDPSAPAA
HGEVAETARTSRLAYQRGLLELIRGDERRALGQLRGVLEPLEAALGDSAAGSACWSALAVLDLLEQGETLDPGQKRAIAA
YDRELRRLLEHGAVGGLPESSMAEALLQPLTEAPGTGRVGQVQAAARRLPGATLAMPPPAEDEAGAASRALVRSDVDLQA
LFYAEVGPALSQIGAALQRWRAGDPEAGLAIQRILHTLKGGARFAGLTEFFAHCHELEGEVATALADGATAGTAQRLRHE
LEQLADRVGVLRREVLGHTAEPGAEPDAEAAAFDYGELWADEDPEPSPAEDGWELQTGSSAEVLGDALAAELAATEDEAA
DADADPPDPATESAPVAEPARDPEPALATLEPDIDALDRQVHATAGEYGRRVELVVEGASRALPEAYLEALRPALEHLLR
NAVRHGIEPPEARSAAGKPEVGRVGLSLRYGQDEVLLVVSDDGAGLDTEALQRQVSDYDPNEPTAALSDDEALSLICLPG
VSTLGPEGDPGAGMGMDEVAGVVHELGGTLEMQSAPGAGARFTLRLPMRGAKAAEQPPGEAPERPRILVLDDSRTMRRIT
GHRLARQGFDPEGAAGLDEARRAVAERAPRAVLIDLEMEMLQHEEGLGVLQRLVAEAGIAAGAVVAVSTRAVDQERLAAA
GLGAARVLLKPYDEGQLADALAQACAALEGGEPG

Sequences:

>Translated_834_residues
MDERRTKAFGVDPRRELTRLLPELRDSVSAAAVRLQEAGDEPGALTALHGELQRLHGGFLFVGVRELEHLSAELRGAAAD
LERAYQSPDEGGVEVQPLRAALMDAVLRLPRAIERIAVRAEDPVAELASLIDGLRRARGQPRYDSLALLRQCVDPSAPAA
HGEVAETARTSRLAYQRGLLELIRGDERRALGQLRGVLEPLEAALGDSAAGSACWSALAVLDLLEQGETLDPGQKRAIAA
YDRELRRLLEHGAVGGLPESSMAEALLQPLTEAPGTGRVGQVQAAARRLPGATLAMPPPAEDEAGAASRALVRSDVDLQA
LFYAEVGPALSQIGAALQRWRAGDPEAGLAIQRILHTLKGGARFAGLTEFFAHCHELEGEVATALADGATAGTAQRLRHE
LEQLADRVGVLRREVLGHTAEPGAEPDAEAAAFDYGELWADEDPEPSPAEDGWELQTGSSAEVLGDALAAELAATEDEAA
DADADPPDPATESAPVAEPARDPEPALATLEPDIDALDRQVHATAGEYGRRVELVVEGASRALPEAYLEALRPALEHLLR
NAVRHGIEPPEARSAAGKPEVGRVGLSLRYGQDEVLLVVSDDGAGLDTEALQRQVSDYDPNEPTAALSDDEALSLICLPG
VSTLGPEGDPGAGMGMDEVAGVVHELGGTLEMQSAPGAGARFTLRLPMRGAKAAEQPPGEAPERPRILVLDDSRTMRRIT
GHRLARQGFDPEGAAGLDEARRAVAERAPRAVLIDLEMEMLQHEEGLGVLQRLVAEAGIAAGAVVAVSTRAVDQERLAAA
GLGAARVLLKPYDEGQLADALAQACAALEGGEPG
>Mature_834_residues
MDERRTKAFGVDPRRELTRLLPELRDSVSAAAVRLQEAGDEPGALTALHGELQRLHGGFLFVGVRELEHLSAELRGAAAD
LERAYQSPDEGGVEVQPLRAALMDAVLRLPRAIERIAVRAEDPVAELASLIDGLRRARGQPRYDSLALLRQCVDPSAPAA
HGEVAETARTSRLAYQRGLLELIRGDERRALGQLRGVLEPLEAALGDSAAGSACWSALAVLDLLEQGETLDPGQKRAIAA
YDRELRRLLEHGAVGGLPESSMAEALLQPLTEAPGTGRVGQVQAAARRLPGATLAMPPPAEDEAGAASRALVRSDVDLQA
LFYAEVGPALSQIGAALQRWRAGDPEAGLAIQRILHTLKGGARFAGLTEFFAHCHELEGEVATALADGATAGTAQRLRHE
LEQLADRVGVLRREVLGHTAEPGAEPDAEAAAFDYGELWADEDPEPSPAEDGWELQTGSSAEVLGDALAAELAATEDEAA
DADADPPDPATESAPVAEPARDPEPALATLEPDIDALDRQVHATAGEYGRRVELVVEGASRALPEAYLEALRPALEHLLR
NAVRHGIEPPEARSAAGKPEVGRVGLSLRYGQDEVLLVVSDDGAGLDTEALQRQVSDYDPNEPTAALSDDEALSLICLPG
VSTLGPEGDPGAGMGMDEVAGVVHELGGTLEMQSAPGAGARFTLRLPMRGAKAAEQPPGEAPERPRILVLDDSRTMRRIT
GHRLARQGFDPEGAAGLDEARRAVAERAPRAVLIDLEMEMLQHEEGLGVLQRLVAEAGIAAGAVVAVSTRAVDQERLAAA
GLGAARVLLKPYDEGQLADALAQACAALEGGEPG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=232, Percent_Identity=34.051724137931, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87873; Mature: 87873

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERRTKAFGVDPRRELTRLLPELRDSVSAAAVRLQEAGDEPGALTALHGELQRLHGGFL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEE
FVGVRELEHLSAELRGAAADLERAYQSPDEGGVEVQPLRAALMDAVLRLPRAIERIAVRA
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EDPVAELASLIDGLRRARGQPRYDSLALLRQCVDPSAPAAHGEVAETARTSRLAYQRGLL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELIRGDERRALGQLRGVLEPLEAALGDSAAGSACWSALAVLDLLEQGETLDPGQKRAIAA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YDRELRRLLEHGAVGGLPESSMAEALLQPLTEAPGTGRVGQVQAAARRLPGATLAMPPPA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
EDEAGAASRALVRSDVDLQALFYAEVGPALSQIGAALQRWRAGDPEAGLAIQRILHTLKG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
GARFAGLTEFFAHCHELEGEVATALADGATAGTAQRLRHELEQLADRVGVLRREVLGHTA
CHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EPGAEPDAEAAAFDYGELWADEDPEPSPAEDGWELQTGSSAEVLGDALAAELAATEDEAA
CCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCC
DADADPPDPATESAPVAEPARDPEPALATLEPDIDALDRQVHATAGEYGRRVELVVEGAS
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCHH
RALPEAYLEALRPALEHLLRNAVRHGIEPPEARSAAGKPEVGRVGLSLRYGQDEVLLVVS
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEEEEECCCCEEEEEC
DDGAGLDTEALQRQVSDYDPNEPTAALSDDEALSLICLPGVSTLGPEGDPGAGMGMDEVA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
GVVHELGGTLEMQSAPGAGARFTLRLPMRGAKAAEQPPGEAPERPRILVLDDSRTMRRIT
HHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
GHRLARQGFDPEGAAGLDEARRAVAERAPRAVLIDLEMEMLQHEEGLGVLQRLVAEAGIA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHCCH
AGAVVAVSTRAVDQERLAAAGLGAARVLLKPYDEGQLADALAQACAALEGGEPG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDERRTKAFGVDPRRELTRLLPELRDSVSAAAVRLQEAGDEPGALTALHGELQRLHGGFL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEE
FVGVRELEHLSAELRGAAADLERAYQSPDEGGVEVQPLRAALMDAVLRLPRAIERIAVRA
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EDPVAELASLIDGLRRARGQPRYDSLALLRQCVDPSAPAAHGEVAETARTSRLAYQRGLL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELIRGDERRALGQLRGVLEPLEAALGDSAAGSACWSALAVLDLLEQGETLDPGQKRAIAA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YDRELRRLLEHGAVGGLPESSMAEALLQPLTEAPGTGRVGQVQAAARRLPGATLAMPPPA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
EDEAGAASRALVRSDVDLQALFYAEVGPALSQIGAALQRWRAGDPEAGLAIQRILHTLKG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
GARFAGLTEFFAHCHELEGEVATALADGATAGTAQRLRHELEQLADRVGVLRREVLGHTA
CHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EPGAEPDAEAAAFDYGELWADEDPEPSPAEDGWELQTGSSAEVLGDALAAELAATEDEAA
CCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCC
DADADPPDPATESAPVAEPARDPEPALATLEPDIDALDRQVHATAGEYGRRVELVVEGAS
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCHH
RALPEAYLEALRPALEHLLRNAVRHGIEPPEARSAAGKPEVGRVGLSLRYGQDEVLLVVS
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEEEEECCCCEEEEEC
DDGAGLDTEALQRQVSDYDPNEPTAALSDDEALSLICLPGVSTLGPEGDPGAGMGMDEVA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
GVVHELGGTLEMQSAPGAGARFTLRLPMRGAKAAEQPPGEAPERPRILVLDDSRTMRRIT
HHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
GHRLARQGFDPEGAAGLDEARRAVAERAPRAVLIDLEMEMLQHEEGLGVLQRLVAEAGIA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHCCH
AGAVVAVSTRAVDQERLAAAGLGAARVLLKPYDEGQLADALAQACAALEGGEPG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]