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The map label for this gene is mltC [C]

Identifier: 121997735

GI number: 121997735

Start: 1021135

End: 1021917

Strand: Reverse

Name: mltC [C]

Synonym: Hhal_0944

Alternate gene names: 121997735

Gene position: 1021917-1021135 (Counterclockwise)

Preceding gene: 121997748

Following gene: 121997725

Centisome position: 38.15

GC content: 71.52

Gene sequence:

>783_bases
ATGCGTATGCACGCCAACTGGCTCATCGGCGGCTGCAGCCTGGTGCTTGCCTCGTTCGGGGCGTACCACCTGCACCACTC
GCCGTGGGCGGCCGAGCGCGGCGGCGGCGCCACGGCCGGCGTCGGCGACTCCGAGCAACTCGAGCGCCTGCGCGCCTCGG
CGGGGATGCCCGAGGTCTCCCGCGCGGTGGTCGAGACCATTGTCGAAGACCGCCAGGCCGAGCGTCACCTGGAAGTCGGC
TCCAACCGCGTCATCCCCCGCAAGCGCCTGGATGAGCTGGTGGACGAGGCGGCCGAGGTGACCGGCCTCAGCGCCGATCT
GATCCGCGCCGTCGTGCGCACCGAGAGCGACTACCGCCCGGGGGTGGTGAGCAGCGCCGGCGCCGTCGGTCTGATGCAGG
TCCGCCCGGTGGCGGCGGTGGACGTCGGTGATCGGGTGCCCGAGTGGCTGGAGCGCTTCAGCGAGCGCGAGGGGCTGGAG
ATCGAGGACGAGGATCTGGCCGACCCGCGGCTGAATGTCCTCATCGGCAGCCACTACCTGGCCCATCTCCACGAGCGCTA
CGCCAGCTACGGCGAGCCGATGGCCACCTGGCTGAGCCTGGCCGCCTACAACTGGGGGCCCGGGAACGTCTATCGCAACC
TGCTCTCCAATCCCAACCTGCAGACCCTCGAGGACCTGCGCTGGCTGCTGCACCGCCGGGCCCCGTACGAGACCCGGGCC
TTCATCGACCGAGTGCTGGAGCGCAGCGGCGCGGCAGGCGAGGAGGCCGGCGAGGCCATCTGA

Upstream 100 bases:

>100_bases
TGACTGCCGCGTCGAACCGCGCCACGGGCGGGGCCCGCTCCTGTCGGTTACCCGTGTTACAGTAGGGAAATTGGCACGGC
TTCGTGGAAGGGGGTGCGTC

Downstream 100 bases:

>100_bases
CCCCGCCGGCGCGCCCCCACGGTCAATGGAGCAGCTGGAATAGCCGCTGGCGGTAGCGGCGGGCCTCCGGGTGCTCCGGG
CCGAGCATGCCGAGCACCTG

Product: lytic transglycosylase catalytic subunit

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Lytic Murein Transglycosylase; Lytic Transglycosylase; Soluble Lytic Murein Transglycosylase; Transglycosylase; Transglycosylase SLT Family Protein; Lytic Transglycosylase Domain-Containing Protein; Transglycosylase SLT Domain Protein

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRMHANWLIGGCSLVLASFGAYHLHHSPWAAERGGGATAGVGDSEQLERLRASAGMPEVSRAVVETIVEDRQAERHLEVG
SNRVIPRKRLDELVDEAAEVTGLSADLIRAVVRTESDYRPGVVSSAGAVGLMQVRPVAAVDVGDRVPEWLERFSEREGLE
IEDEDLADPRLNVLIGSHYLAHLHERYASYGEPMATWLSLAAYNWGPGNVYRNLLSNPNLQTLEDLRWLLHRRAPYETRA
FIDRVLERSGAAGEEAGEAI

Sequences:

>Translated_260_residues
MRMHANWLIGGCSLVLASFGAYHLHHSPWAAERGGGATAGVGDSEQLERLRASAGMPEVSRAVVETIVEDRQAERHLEVG
SNRVIPRKRLDELVDEAAEVTGLSADLIRAVVRTESDYRPGVVSSAGAVGLMQVRPVAAVDVGDRVPEWLERFSEREGLE
IEDEDLADPRLNVLIGSHYLAHLHERYASYGEPMATWLSLAAYNWGPGNVYRNLLSNPNLQTLEDLRWLLHRRAPYETRA
FIDRVLERSGAAGEEAGEAI
>Mature_260_residues
MRMHANWLIGGCSLVLASFGAYHLHHSPWAAERGGGATAGVGDSEQLERLRASAGMPEVSRAVVETIVEDRQAERHLEVG
SNRVIPRKRLDELVDEAAEVTGLSADLIRAVVRTESDYRPGVVSSAGAVGLMQVRPVAAVDVGDRVPEWLERFSEREGLE
IEDEDLADPRLNVLIGSHYLAHLHERYASYGEPMATWLSLAAYNWGPGNVYRNLLSNPNLQTLEDLRWLLHRRAPYETRA
FIDRVLERSGAAGEEAGEAI

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 28712; Mature: 28712

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMHANWLIGGCSLVLASFGAYHLHHSPWAAERGGGATAGVGDSEQLERLRASAGMPEVS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHH
RAVVETIVEDRQAERHLEVGSNRVIPRKRLDELVDEAAEVTGLSADLIRAVVRTESDYRP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
GVVSSAGAVGLMQVRPVAAVDVGDRVPEWLERFSEREGLEIEDEDLADPRLNVLIGSHYL
CCCCCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
AHLHERYASYGEPMATWLSLAAYNWGPGNVYRNLLSNPNLQTLEDLRWLLHRRAPYETRA
HHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
FIDRVLERSGAAGEEAGEAI
HHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRMHANWLIGGCSLVLASFGAYHLHHSPWAAERGGGATAGVGDSEQLERLRASAGMPEVS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHH
RAVVETIVEDRQAERHLEVGSNRVIPRKRLDELVDEAAEVTGLSADLIRAVVRTESDYRP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
GVVSSAGAVGLMQVRPVAAVDVGDRVPEWLERFSEREGLEIEDEDLADPRLNVLIGSHYL
CCCCCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
AHLHERYASYGEPMATWLSLAAYNWGPGNVYRNLLSNPNLQTLEDLRWLLHRRAPYETRA
HHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
FIDRVLERSGAAGEEAGEAI
HHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA