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The map label for this gene is corC [H]

Identifier: 121997681

GI number: 121997681

Start: 967466

End: 968341

Strand: Reverse

Name: corC [H]

Synonym: Hhal_0890

Alternate gene names: 121997681

Gene position: 968341-967466 (Counterclockwise)

Preceding gene: 121997682

Following gene: 121997680

Centisome position: 36.15

GC content: 67.47

Gene sequence:

>876_bases
ATGCCCGACGGAGAAGCGAACAGTAGCAACGGCGCCGGCGAGAGCGTCTCATGGCGTGATCGCCTGCGCCGGCTAGTCAC
CCAGGTGGAGCCCCGTTCGCGGGATGAACTGGTCGATCATCTGCGCCGCAGCCAGTCGGTGGGGCTGCTCGACGCCGACG
CCCTGTCCATGATCGAGGGCGTGCTCCACGTCTCCGAGCTCCAGGCCCGGGATATCATGATCCCCCGCTCCCAGGTCACC
ACCGTGGCCCGGGACACCGCGCCCCACGACTTGCTGCCGACCATCGTGCGCACCGGCTACTCCCGCTTCCCGGTCACCGG
CGAGAGCAAGGACGATGTCATCGGCATCCTCCTCGCTAAGGACCTGCTGCGGCTCTTCTACGAAGAGGGGCACAACGGCT
TCCGGCTGCGTGAGGTCCTGCGCCCGGTCCTGTTCATCCCCGAGAGCAAGCGGCTCGACGCGTTGCTCAAGCAGTTCCGC
GAGAGCCGCAACCACATGTCGGTGGTGGTGGACGAGTACGGCGGTCTGGCCGGCATCGTCACCATCGAGGACGTGATCGA
GCAGATCGTCGGCGAGATCGACGACGAGCACGACTTCGACGAGGACGCCCCCATCCTGGCCCGGGACGACGGCAGCTGGA
TCGTCAAGGCGGTCACGCCCATCGAGGCGTTCAACGAGGCCCTCTCCGCCGGGCTCAAGGAGGATGACCTCGACACGGTT
GGTGGCCTGGTGGCGCAGCGTTTCGGCCACGTGCCGTGCCGCGGCGAGCGCATCGTCTTTGCCGGCTTCGAGTTCCGGGT
GCTGCGCGCCGATCAGCGCCGCATCCACCTGCTGCGGGTCATGCCCGTGGGAAGTGAGGGCCATGAGGACGGCTGA

Upstream 100 bases:

>100_bases
ACGAGGACCCGGCGCAGGCCGAGCGGATGGAGGCCGAGGAGCGCCGCATCCTGGCCGCGCTCGGGGTGCCCGATCCCTAC
CAGGAGCGTTGAAACAGGCA

Downstream 100 bases:

>100_bases
GCGCCTGGCCGCCGGGCGTGCCGGTGTGCTCGCGGCCGGGCTGGCTGGGGGTTTGCTGCCCCTGGCGTTGGCCCCGCTGG
GCTGGGCCGTGCTGGCGGTG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEGVLHVSELQARDIMIPRSQVT
TVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAKDLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFR
ESRNHMSVVVDEYGGLAGIVTIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV
GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHEDG

Sequences:

>Translated_291_residues
MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEGVLHVSELQARDIMIPRSQVT
TVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAKDLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFR
ESRNHMSVVVDEYGGLAGIVTIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV
GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHEDG
>Mature_290_residues
PDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEGVLHVSELQARDIMIPRSQVTT
VARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAKDLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRE
SRNHMSVVVDEYGGLAGIVTIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTVG
GLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHEDG

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=218, Percent_Identity=31.1926605504587, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI94681046, Length=184, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40068053, Length=184, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40068055, Length=184, Percent_Identity=27.1739130434783, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786879, Length=275, Percent_Identity=43.6363636363636, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI145693175, Length=230, Percent_Identity=27.3913043478261, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082033, Length=242, Percent_Identity=28.9256198347107, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788119, Length=227, Percent_Identity=32.5991189427313, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790664, Length=234, Percent_Identity=26.4957264957265, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32492; Mature: 32361

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLHVSELQARDIMIPRSQVTTVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAK
HHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
DLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRESRNHMSVVVDEYGGLAGIV
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEE
TIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV
EHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHCCCCCCHHHHH
GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHEDG
HHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
PDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLHVSELQARDIMIPRSQVTTVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAK
HHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
DLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRESRNHMSVVVDEYGGLAGIV
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEE
TIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV
EHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHCCCCCCHHHHH
GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHEDG
HHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]