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The map label for this gene is nuoN [H]

Identifier: 121997604

GI number: 121997604

Start: 896949

End: 898412

Strand: Reverse

Name: nuoN [H]

Synonym: Hhal_0813

Alternate gene names: 121997604

Gene position: 898412-896949 (Counterclockwise)

Preceding gene: 121997605

Following gene: 121997603

Centisome position: 33.54

GC content: 72.81

Gene sequence:

>1464_bases
GTGGCCGGGGTGTCGCTGCCGCTGGCTTTCTTCCTGCCGCTGCTCACCGCGCTGGTGGTCTTCCTGGTGCGCGCCCGGCG
GGCGCCGTGGCTGCCCCTGCTCGGCGCCCTGGCCACCGTGGCGACGGTGGCCGACGTGGTTCGTCAGGTGGCCGAGCACG
GCCCGCAGAGCCACCACCTGGGTGGTTGGGAGCCGCCGCTGGGCGTGGAGCTCTACGCCGACGGCCTCTCGGCCCTGATG
CTCGGCATGACCGCCGTGGTGGGGCTGGCGGTGACCCTCTACGCCGGCCCCTACCTGCGCGGCAAGGGCTACAACACCGA
GCTGTTCTGGCCGCTGTGGCTGGTGCAGTGGGCCACCCTCAACGGCACCTTCCTCTCGGCGGACCTGTTCAACCTCTACG
TCATGCTGGAGCTGCTCACCCTCACGGCGGCTCCGCTGGCGGCCATGGCCGGCGACCGGCCCTCGCTGGGCGCGGCCATG
CGCTACCTGCTGCTGGCCCTGCTCGGTTCCCTGGCCTACCTGCTGGGGGTGGCGCTGCTCTACGGCGGCACCGGCACCCT
GCACCTGCGCGAGGTCGGCGAGCTGGTCGGCGCCGATGGCTACACCGCCGTGGCGGCGGCGCTGATCACCGCCGGACTGT
TCGCCAAGGCGGCGGTCTTTCCGCTGCACATCTGGCTGATGCCGGCGCACAGTAACGCCCCGGCGCCGGCCAGCGCGGCG
CTCTCGGCGCTGGTTGCCAAGGCCGGCATCTACCTGGTGCTGCGCCTGTGGCTGTGGGTCTTCCCGGTGCTGCTGAGCAC
CTACATGGGTTGGCTGATCGGCGCCCTGGGGGCGCTGGCGGTGCTCTACGGCTCGCTGCAGGCCCTGCGCCAGCCCCGGC
TCAAGCAGGTCATCGCCTACTCGACCATCGCCCAGCTCGGCTACCTGCTGCTGCTCCTGCCGCTGGTGGTGGTCCCCGCC
GCCGCGGTGCAGGCCTGGCAGGGGGTGGCCTACCACGCCCTGGCCCACGGCTTCGCCAAGTCCGCCGCCTTCCTGGCCGC
CGGCAACATGCTCTACAGCCTCGGTCACGACCGGCTCGAGGGGCTGCGCGGGCTCACGCCGTACCTGTCGATCACCGTGC
TGACCCTGGGGCTGGCCTTCGCCAGCCTCATGGCCTTGCCGCCCAGCGGCGGCTTCCTGGCCAAGTGGCTGCTGCTCAGC
GGCGCCATCAGCGGCGGGCAGTGGCTGTGGGCGGTGGTGATCATCCTCGGTAGCGTGCTCGCCGCCGCCTACGCCTTCCG
CGTGCTGGCGCTGGCCCACGCCGCGCCGCCGGCCGGGTACACCGAGGTGCGCCCGGCGCAGCGGGTGCCGCGGATCATGG
AGTGGGTGCCGCTGCTGCTGGTGCTGGTGGTCTACGCCCTGGGGATCAGCGCCATGCCGGCGCTGGGGCTGCTCGAGCAG
GGCGCACCGGAGGGGCTGGAATGA

Upstream 100 bases:

>100_bases
CGTCATCGCCGTCAGCGCCACCGCCTTCGCCCTGGTGCTGGCGCGCCGCTACTACGCCGAGACCGGCCTCAACCACCTGC
CCGAGGACGAGGACTAGACC

Downstream 100 bases:

>100_bases
TCGATACACTCCACGCGCTGCTGCCGCTGTGGGCGCTGCTGGCCTCGCTGCTCACCGCGGTGATCATCTTCGCCCTGCGC
GACGAGCGCCGCCGCCAGCG

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MAGVSLPLAFFLPLLTALVVFLVRARRAPWLPLLGALATVATVADVVRQVAEHGPQSHHLGGWEPPLGVELYADGLSALM
LGMTAVVGLAVTLYAGPYLRGKGYNTELFWPLWLVQWATLNGTFLSADLFNLYVMLELLTLTAAPLAAMAGDRPSLGAAM
RYLLLALLGSLAYLLGVALLYGGTGTLHLREVGELVGADGYTAVAAALITAGLFAKAAVFPLHIWLMPAHSNAPAPASAA
LSALVAKAGIYLVLRLWLWVFPVLLSTYMGWLIGALGALAVLYGSLQALRQPRLKQVIAYSTIAQLGYLLLLLPLVVVPA
AAVQAWQGVAYHALAHGFAKSAAFLAAGNMLYSLGHDRLEGLRGLTPYLSITVLTLGLAFASLMALPPSGGFLAKWLLLS
GAISGGQWLWAVVIILGSVLAAAYAFRVLALAHAAPPAGYTEVRPAQRVPRIMEWVPLLLVLVVYALGISAMPALGLLEQ
GAPEGLE

Sequences:

>Translated_487_residues
MAGVSLPLAFFLPLLTALVVFLVRARRAPWLPLLGALATVATVADVVRQVAEHGPQSHHLGGWEPPLGVELYADGLSALM
LGMTAVVGLAVTLYAGPYLRGKGYNTELFWPLWLVQWATLNGTFLSADLFNLYVMLELLTLTAAPLAAMAGDRPSLGAAM
RYLLLALLGSLAYLLGVALLYGGTGTLHLREVGELVGADGYTAVAAALITAGLFAKAAVFPLHIWLMPAHSNAPAPASAA
LSALVAKAGIYLVLRLWLWVFPVLLSTYMGWLIGALGALAVLYGSLQALRQPRLKQVIAYSTIAQLGYLLLLLPLVVVPA
AAVQAWQGVAYHALAHGFAKSAAFLAAGNMLYSLGHDRLEGLRGLTPYLSITVLTLGLAFASLMALPPSGGFLAKWLLLS
GAISGGQWLWAVVIILGSVLAAAYAFRVLALAHAAPPAGYTEVRPAQRVPRIMEWVPLLLVLVVYALGISAMPALGLLEQ
GAPEGLE
>Mature_486_residues
AGVSLPLAFFLPLLTALVVFLVRARRAPWLPLLGALATVATVADVVRQVAEHGPQSHHLGGWEPPLGVELYADGLSALML
GMTAVVGLAVTLYAGPYLRGKGYNTELFWPLWLVQWATLNGTFLSADLFNLYVMLELLTLTAAPLAAMAGDRPSLGAAMR
YLLLALLGSLAYLLGVALLYGGTGTLHLREVGELVGADGYTAVAAALITAGLFAKAAVFPLHIWLMPAHSNAPAPASAAL
SALVAKAGIYLVLRLWLWVFPVLLSTYMGWLIGALGALAVLYGSLQALRQPRLKQVIAYSTIAQLGYLLLLLPLVVVPAA
AVQAWQGVAYHALAHGFAKSAAFLAAGNMLYSLGHDRLEGLRGLTPYLSITVLTLGLAFASLMALPPSGGFLAKWLLLSG
AISGGQWLWAVVIILGSVLAAAYAFRVLALAHAAPPAGYTEVRPAQRVPRIMEWVPLLLVLVVYALGISAMPALGLLEQG
APEGLE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831116, Length=257, Percent_Identity=28.4046692607004, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI251831117, Length=243, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788614, Length=488, Percent_Identity=28.8934426229508, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788829, Length=478, Percent_Identity=29.2887029288703, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788827, Length=345, Percent_Identity=28.1159420289855, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788831, Length=362, Percent_Identity=25.414364640884, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693160, Length=430, Percent_Identity=26.9767441860465, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788613, Length=416, Percent_Identity=27.1634615384615, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51279; Mature: 51148

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVSLPLAFFLPLLTALVVFLVRARRAPWLPLLGALATVATVADVVRQVAEHGPQSHHL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGWEPPLGVELYADGLSALMLGMTAVVGLAVTLYAGPYLRGKGYNTELFWPLWLVQWATL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
NGTFLSADLFNLYVMLELLTLTAAPLAAMAGDRPSLGAAMRYLLLALLGSLAYLLGVALL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGGTGTLHLREVGELVGADGYTAVAAALITAGLFAKAAVFPLHIWLMPAHSNAPAPASAA
HCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHH
LSALVAKAGIYLVLRLWLWVFPVLLSTYMGWLIGALGALAVLYGSLQALRQPRLKQVIAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
STIAQLGYLLLLLPLVVVPAAAVQAWQGVAYHALAHGFAKSAAFLAAGNMLYSLGHDRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GLRGLTPYLSITVLTLGLAFASLMALPPSGGFLAKWLLLSGAISGGQWLWAVVIILGSVL
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAAYAFRVLALAHAAPPAGYTEVRPAQRVPRIMEWVPLLLVLVVYALGISAMPALGLLEQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAPEGLE
CCCCCCC
>Mature Secondary Structure 
AGVSLPLAFFLPLLTALVVFLVRARRAPWLPLLGALATVATVADVVRQVAEHGPQSHHL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGWEPPLGVELYADGLSALMLGMTAVVGLAVTLYAGPYLRGKGYNTELFWPLWLVQWATL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
NGTFLSADLFNLYVMLELLTLTAAPLAAMAGDRPSLGAAMRYLLLALLGSLAYLLGVALL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGGTGTLHLREVGELVGADGYTAVAAALITAGLFAKAAVFPLHIWLMPAHSNAPAPASAA
HCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHH
LSALVAKAGIYLVLRLWLWVFPVLLSTYMGWLIGALGALAVLYGSLQALRQPRLKQVIAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
STIAQLGYLLLLLPLVVVPAAAVQAWQGVAYHALAHGFAKSAAFLAAGNMLYSLGHDRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GLRGLTPYLSITVLTLGLAFASLMALPPSGGFLAKWLLLSGAISGGQWLWAVVIILGSVL
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAAYAFRVLALAHAAPPAGYTEVRPAQRVPRIMEWVPLLLVLVVYALGISAMPALGLLEQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAPEGLE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA