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The map label for this gene is yoeB [H]

Identifier: 121997584

GI number: 121997584

Start: 875921

End: 876175

Strand: Reverse

Name: yoeB [H]

Synonym: Hhal_0793

Alternate gene names: 121997584

Gene position: 876175-875921 (Counterclockwise)

Preceding gene: 121997585

Following gene: 121997577

Centisome position: 32.71

GC content: 60.0

Gene sequence:

>255_bases
ATGAGGCTGATCTTCTCCGAGAACGCCTGGGAAGACTACCTCTATTGGCAAAAGAACGATAAGGCGACCCTGCGGCGGAT
CAACAAGCTGATCCGGGAGACCCAGCGCGCGCCCTTTGAGGGCCTCGGCAAGCCCGAGCCACTCAAGCACGGCCTTGCCG
GCTACTGGTCTCGCCGGATCGATGAGGAGTACCGGATGGTGTACAAAGTCGGGGACGACGGGCTCTTGATCGCGCAGCTC
CGCTATCACTATTGA

Upstream 100 bases:

>100_bases
AGACTGCTTACCTGCTCCGCTCCCCGAAGAATGCTCGGCGTCTGCTGGAGTCCGTCGCCGATTTGGAACGGGGTGGTGGC
CAGGAGAGGGACCTTATGGA

Downstream 100 bases:

>100_bases
TGTCCAAGCCCGCTCCGGCTCGTTGCGGCCTGCGGTGCCCATCCGGCGCCGACAGGGGCCGGCCCTCTTGGCGTCGAGCC
GCCATTATGCGCCCGTAGTG

Product: addiction module antitoxin

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MRLIFSENAWEDYLYWQKNDKATLRRINKLIRETQRAPFEGLGKPEPLKHGLAGYWSRRIDEEYRMVYKVGDDGLLIAQL
RYHY

Sequences:

>Translated_84_residues
MRLIFSENAWEDYLYWQKNDKATLRRINKLIRETQRAPFEGLGKPEPLKHGLAGYWSRRIDEEYRMVYKVGDDGLLIAQL
RYHY
>Mature_84_residues
MRLIFSENAWEDYLYWQKNDKATLRRINKLIRETQRAPFEGLGKPEPLKHGLAGYWSRRIDEEYRMVYKVGDDGLLIAQL
RYHY

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=84, Percent_Identity=65.4761904761905, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10192; Mature: 10192

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIFSENAWEDYLYWQKNDKATLRRINKLIRETQRAPFEGLGKPEPLKHGLAGYWSRRI
CEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
DEEYRMVYKVGDDGLLIAQLRYHY
CHHHHEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MRLIFSENAWEDYLYWQKNDKATLRRINKLIRETQRAPFEGLGKPEPLKHGLAGYWSRRI
CEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
DEEYRMVYKVGDDGLLIAQLRYHY
CHHHHEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]