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The map label for this gene is argD [H]

Identifier: 121997524

GI number: 121997524

Start: 812702

End: 813871

Strand: Reverse

Name: argD [H]

Synonym: Hhal_0727

Alternate gene names: 121997524

Gene position: 813871-812702 (Counterclockwise)

Preceding gene: 121997525

Following gene: 121997523

Centisome position: 30.39

GC content: 75.21

Gene sequence:

>1170_bases
ATGCAAGCCCTGATCCCCACCTACAACCGCCTGCCCGTCGCCTTCACCCGGGGTGAGGGGGCGTGGCTGTACGACGAGCA
GGGTCACGCCTATCTCGACGGCGTGGCCGGTATCGCCGTGTGCGGGCTGGGCCACAGCCATCCGGCCATCGCCCGGGTGG
TGGCCGAGCAGGCGCAGACCCTGGTGCACACCTCCAACCTCTACCGGGTGCCGCTGCAGGAACGCCTGGCCGAGCGCCTG
TGCGCCGCCGCCGGGATGGGCGCGGCGTTTTTCTGCAACTCCGGGGCCGAGGCCAACGAGGCGGCCATCAAACTGGCCCG
CCGGTATGCGGCCGGCCGCGGCATCACGGCGCCGCAGATCGTGGTGGCCGACGGCGCCTTCCACGGCCGGACCCTGGGGG
CGCTGGCGGCCACCGGGAACCCGCAGGCCCACGAGGGGTTCGCGCCGCTGCCCGAGGGCTTCCTGCGTGTGCCCTACGGG
GATGCCGACGCGGTGGCGGCCGTCGACGATCCGGCGGTCTGCGCCGTGCTGGTCGAGCCGATCCAGGGCGAGGGCGGGGT
GCAGATCCCGCCGGCGGACTACCTGGCGCGGCTGCGCCGGCTCTGCGACGAGCGCGGCTGGCTGCTGATGCTCGACGAGG
TGCAGACCGGCATGGGGCGGACCGGCACGCTGTTCGCCTTCGAGCAGGCCGGCATCCGCCCGGACGTCCTGGTGCTGGCC
AAGGCCCTGGGCAACGGTCTGCCCATCGGCGCCTGCCTGGCCGCCGCCGAGCACGCCGAGATCCTTGGCCCCGGCAGCCA
CGGCACGACCTACGGCGGCAATCCGCTGGCCGCCCGGGCGGCGCTGGCGGTGCTCGACACCCTCGAGGGCGAGGACCTGC
CGGCGGCCGCCGCCCGAGCCGGCGAGGCGCTGCGTGCCCGCCTGGCCGAGGGGCTGGCCGGTGTCGACGGGGTGCGGGAG
ATCCGCGGCCGCGGGCTGATGGTCGGCGTCGAGCTCGCCGTGGAGGCCAGCGCCCTGCCGCGCCAGGCCCTGGAGGCCGG
ACTGCTGATCAACGTGACCGCCGGCCGCGTGGTCCGGCTGGTCCCGCCGCTGACCCTGGACGATGATGAGATCCGCCAGC
TCGCCGACGGCGTCGTCGACCTAGTGCGCCGCCACCTGGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCCAAGGGGTTGCGGTGCTTGCGCCGGGTCCCGTCGGCGGTTAGGTTAGACGTTTTTTCCCGGCTTCTAGAGCCGGTTCC
ATGCGGGTATGAAACGGTCC

Downstream 100 bases:

>100_bases
CCTGAACCGAACCAAGGAGGGCGTCCTGGATGCGCCACTTCCTCACCCTGCGTGACTGCTCCGTCGACGAGATCCACCAG
CTGCTGCGCCGGGCCACGGA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQALIPTYNRLPVAFTRGEGAWLYDEQGHAYLDGVAGIAVCGLGHSHPAIARVVAEQAQTLVHTSNLYRVPLQERLAERL
CAAAGMGAAFFCNSGAEANEAAIKLARRYAAGRGITAPQIVVADGAFHGRTLGALAATGNPQAHEGFAPLPEGFLRVPYG
DADAVAAVDDPAVCAVLVEPIQGEGGVQIPPADYLARLRRLCDERGWLLMLDEVQTGMGRTGTLFAFEQAGIRPDVLVLA
KALGNGLPIGACLAAAEHAEILGPGSHGTTYGGNPLAARAALAVLDTLEGEDLPAAAARAGEALRARLAEGLAGVDGVRE
IRGRGLMVGVELAVEASALPRQALEAGLLINVTAGRVVRLVPPLTLDDDEIRQLADGVVDLVRRHLAGA

Sequences:

>Translated_389_residues
MQALIPTYNRLPVAFTRGEGAWLYDEQGHAYLDGVAGIAVCGLGHSHPAIARVVAEQAQTLVHTSNLYRVPLQERLAERL
CAAAGMGAAFFCNSGAEANEAAIKLARRYAAGRGITAPQIVVADGAFHGRTLGALAATGNPQAHEGFAPLPEGFLRVPYG
DADAVAAVDDPAVCAVLVEPIQGEGGVQIPPADYLARLRRLCDERGWLLMLDEVQTGMGRTGTLFAFEQAGIRPDVLVLA
KALGNGLPIGACLAAAEHAEILGPGSHGTTYGGNPLAARAALAVLDTLEGEDLPAAAARAGEALRARLAEGLAGVDGVRE
IRGRGLMVGVELAVEASALPRQALEAGLLINVTAGRVVRLVPPLTLDDDEIRQLADGVVDLVRRHLAGA
>Mature_389_residues
MQALIPTYNRLPVAFTRGEGAWLYDEQGHAYLDGVAGIAVCGLGHSHPAIARVVAEQAQTLVHTSNLYRVPLQERLAERL
CAAAGMGAAFFCNSGAEANEAAIKLARRYAAGRGITAPQIVVADGAFHGRTLGALAATGNPQAHEGFAPLPEGFLRVPYG
DADAVAAVDDPAVCAVLVEPIQGEGGVQIPPADYLARLRRLCDERGWLLMLDEVQTGMGRTGTLFAFEQAGIRPDVLVLA
KALGNGLPIGACLAAAEHAEILGPGSHGTTYGGNPLAARAALAVLDTLEGEDLPAAAARAGEALRARLAEGLAGVDGVRE
IRGRGLMVGVELAVEASALPRQALEAGLLINVTAGRVVRLVPPLTLDDDEIRQLADGVVDLVRRHLAGA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=376, Percent_Identity=37.2340425531915, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=40.3448275862069, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI13994255, Length=444, Percent_Identity=28.8288288288288, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=28.992628992629, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=31.3084112149533, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=28.009828009828, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI226442709, Length=376, Percent_Identity=28.9893617021277, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=25.4672897196262, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=25.4672897196262, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=25.4672897196262, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=42.6666666666667, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=41.2073490813648, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI145693181, Length=399, Percent_Identity=41.1027568922306, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=35.8395989974937, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=35.1758793969849, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786991, Length=406, Percent_Identity=30.7881773399015, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=32.1766561514196, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=36.8146214099217, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI32564660, Length=450, Percent_Identity=32.2222222222222, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=267, Percent_Identity=37.8277153558052, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=26.3403263403263, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=34.8101265822785, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=25.4004576659039, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=389, Percent_Identity=38.560411311054, Blast_Score=250, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=35.5498721227622, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6321456, Length=430, Percent_Identity=26.046511627907, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324386, Length=418, Percent_Identity=21.7703349282297, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=36.4341085271318, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=30.2961275626424, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28574759, Length=369, Percent_Identity=33.6043360433604, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356575, Length=415, Percent_Identity=28.433734939759, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI281366494, Length=379, Percent_Identity=26.1213720316623, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=379, Percent_Identity=26.1213720316623, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=379, Percent_Identity=26.1213720316623, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 40339; Mature: 40339

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALIPTYNRLPVAFTRGEGAWLYDEQGHAYLDGVAGIAVCGLGHSHPAIARVVAEQAQT
CCCCCCCCCCCCEEEECCCCEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LVHTSNLYRVPLQERLAERLCAAAGMGAAFFCNSGAEANEAAIKLARRYAAGRGITAPQI
HHHHCCEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEE
VVADGAFHGRTLGALAATGNPQAHEGFAPLPEGFLRVPYGDADAVAAVDDPAVCAVLVEP
EEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEEEEEC
IQGEGGVQIPPADYLARLRRLCDERGWLLMLDEVQTGMGRTGTLFAFEQAGIRPDVLVLA
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHH
KALGNGLPIGACLAAAEHAEILGPGSHGTTYGGNPLAARAALAVLDTLEGEDLPAAAARA
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
GEALRARLAEGLAGVDGVREIRGRGLMVGVELAVEASALPRQALEAGLLINVTAGRVVRL
HHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEECHHHCCHHHHHCCEEEEECCCCEEEE
VPPLTLDDDEIRQLADGVVDLVRRHLAGA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQALIPTYNRLPVAFTRGEGAWLYDEQGHAYLDGVAGIAVCGLGHSHPAIARVVAEQAQT
CCCCCCCCCCCCEEEECCCCEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LVHTSNLYRVPLQERLAERLCAAAGMGAAFFCNSGAEANEAAIKLARRYAAGRGITAPQI
HHHHCCEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEE
VVADGAFHGRTLGALAATGNPQAHEGFAPLPEGFLRVPYGDADAVAAVDDPAVCAVLVEP
EEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCEEECCCCCEEEEEEEC
IQGEGGVQIPPADYLARLRRLCDERGWLLMLDEVQTGMGRTGTLFAFEQAGIRPDVLVLA
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHH
KALGNGLPIGACLAAAEHAEILGPGSHGTTYGGNPLAARAALAVLDTLEGEDLPAAAARA
HHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
GEALRARLAEGLAGVDGVREIRGRGLMVGVELAVEASALPRQALEAGLLINVTAGRVVRL
HHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEECHHHCCHHHHHCCEEEEECCCCEEEE
VPPLTLDDDEIRQLADGVVDLVRRHLAGA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]