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The map label for this gene is hda [H]

Identifier: 121997504

GI number: 121997504

Start: 790474

End: 791199

Strand: Reverse

Name: hda [H]

Synonym: Hhal_0707

Alternate gene names: 121997504

Gene position: 791199-790474 (Counterclockwise)

Preceding gene: 121997506

Following gene: 121997501

Centisome position: 29.54

GC content: 73.83

Gene sequence:

>726_bases
GTGCAACTGCCACTGAACATCCGCTGGAACGCCGCCGCCGAGCTCGATCGGTTCGTCCCCGGCGAGAACGACACGGCCCT
GCGCCTGGTCACCGACCTGGCCGACGGCCTGCTGGAGGCGCCGGCGCTCTACCTGCACGGCCCCCACGGGGTCGGCAAGA
GCCACCTGCTCCAGGGGGCCTGCCGCCGCGTGACCACCGCTGGCGGGGTGGCGGTCTACCTGCCGCTGGATCAGCTGCTC
GGCCACGGCGCGGCGGTGCTCGACGGCTGGGAGCAGGCGCAGCTGATCGCCCTCGACGACCTCGATGCGCTGGACGGGCG
CGATGAGTGGCAGGGCGCGGTCTTCCACCTCTACAACCGGGTGGTGGAGCGCGGCGGACGGTTGCTCTTCGCCGGGCGTC
AGCCGCCGGCGGAGCTGCCGCTGGACCTGCCGGATCTGCGCTCGCGTCTGGGCTGGGGGCCGGTGGTGGCGGTGCGCGAG
CCCGATGAAACCACCTGCCTGGCCATCCTCCGCCAGCGCGCCGCGCAGCGCGGGCTCGAGCTGCCCGACGCCACCGCGCG
CTACCTGATCCGCCGGCTGCCCCGGGAGCTGCCCGGTCTGCTGGCCTTCTTCGAGACCCTGGACCGCGCCTCGCTGGCCG
CCGGGCGGCGGCTTACGGTCCCGTTCGTTCGCGAGATCCTGGCCGAGCGCTCCCGGCCTGACGCAGATACATCAGGGCAG
CCGTGA

Upstream 100 bases:

>100_bases
GCGAGGTTACCAGTCCTGCCGTTTCGGACAAGGCGGCGCTTGACAGGGCGGCGGCGGCGCCCTGGAATGAGCCCACCCGC
AATACCCACCGGGGGGATCG

Downstream 100 bases:

>100_bases
AGTAGACCACCGCCAGGACGATCTCGACGATCCCCAGCCACCGCTCCGGGCCGGGCACCGCGGCGTAGGTGACGCCGTGG
ATGAAGTAGATCAGCACGAA

Product: chromosomal replication initiator, DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MQLPLNIRWNAAAELDRFVPGENDTALRLVTDLADGLLEAPALYLHGPHGVGKSHLLQGACRRVTTAGGVAVYLPLDQLL
GHGAAVLDGWEQAQLIALDDLDALDGRDEWQGAVFHLYNRVVERGGRLLFAGRQPPAELPLDLPDLRSRLGWGPVVAVRE
PDETTCLAILRQRAAQRGLELPDATARYLIRRLPRELPGLLAFFETLDRASLAAGRRLTVPFVREILAERSRPDADTSGQ
P

Sequences:

>Translated_241_residues
MQLPLNIRWNAAAELDRFVPGENDTALRLVTDLADGLLEAPALYLHGPHGVGKSHLLQGACRRVTTAGGVAVYLPLDQLL
GHGAAVLDGWEQAQLIALDDLDALDGRDEWQGAVFHLYNRVVERGGRLLFAGRQPPAELPLDLPDLRSRLGWGPVVAVRE
PDETTCLAILRQRAAQRGLELPDATARYLIRRLPRELPGLLAFFETLDRASLAAGRRLTVPFVREILAERSRPDADTSGQ
P
>Mature_241_residues
MQLPLNIRWNAAAELDRFVPGENDTALRLVTDLADGLLEAPALYLHGPHGVGKSHLLQGACRRVTTAGGVAVYLPLDQLL
GHGAAVLDGWEQAQLIALDDLDALDGRDEWQGAVFHLYNRVVERGGRLLFAGRQPPAELPLDLPDLRSRLGWGPVVAVRE
PDETTCLAILRQRAAQRGLELPDATARYLIRRLPRELPGLLAFFETLDRASLAAGRRLTVPFVREILAERSRPDADTSGQ
P

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=211, Percent_Identity=40.2843601895735, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI2367267, Length=236, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 26419; Mature: 26419

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPLNIRWNAAAELDRFVPGENDTALRLVTDLADGLLEAPALYLHGPHGVGKSHLLQGA
CCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
CRRVTTAGGVAVYLPLDQLLGHGAAVLDGWEQAQLIALDDLDALDGRDEWQGAVFHLYNR
HHHHHCCCCEEEEEEHHHHHCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VVERGGRLLFAGRQPPAELPLDLPDLRSRLGWGPVVAVREPDETTCLAILRQRAAQRGLE
HHHHCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
LPDATARYLIRRLPRELPGLLAFFETLDRASLAAGRRLTVPFVREILAERSRPDADTSGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
P
C
>Mature Secondary Structure
MQLPLNIRWNAAAELDRFVPGENDTALRLVTDLADGLLEAPALYLHGPHGVGKSHLLQGA
CCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
CRRVTTAGGVAVYLPLDQLLGHGAAVLDGWEQAQLIALDDLDALDGRDEWQGAVFHLYNR
HHHHHCCCCEEEEEEHHHHHCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VVERGGRLLFAGRQPPAELPLDLPDLRSRLGWGPVVAVREPDETTCLAILRQRAAQRGLE
HHHHCCEEEEECCCCCCCCCCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
LPDATARYLIRRLPRELPGLLAFFETLDRASLAAGRRLTVPFVREILAERSRPDADTSGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA