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The map label for this gene is serC [H]

Identifier: 121997371

GI number: 121997371

Start: 645132

End: 646211

Strand: Reverse

Name: serC [H]

Synonym: Hhal_0570

Alternate gene names: 121997371

Gene position: 646211-645132 (Counterclockwise)

Preceding gene: 121997372

Following gene: 121997370

Centisome position: 24.13

GC content: 66.11

Gene sequence:

>1080_bases
ATGAGTAGAGTCTTCAACTTCAGTGCCGGCCCGGCCATGCTCCCCGAGGCGGTGATGCGCCAGGCCGCCGAGGAGATGCT
CGATTGGCAGGGCACCGGCATGTCGGTCATGGAGATGAGCCACCGTGGCAAGGCATACGTCTCCATCGCCGAGAAGGCCG
AGGCCGATCTGCGGGCGTTGCTGCAGATCCCGGACAACTACAAGGTCCTGTTCCTGCAGGGCGGGGCCACCGGACAGTTC
TCGGCCATCCCCATGAACCTGCTGCGTGGCGGCAAGCGCGCCGACTACATCTACACCGGTCAGTGGTCGAAGAAGGCCAT
CGCCGAGGCGAAGAAGTTCTGCGAGGTCAACGTTGCCGCCTCCGGCGAGCCGGACATGATGCACGTGCCGCCGCAGTCGC
AGTGGCAGCTCTCCGACGACGCCGCCTACGTCCACTTCACCCCCAACGAGACCATCAGCGGCGTGGAGTTCCACTGGCTG
CCCGACGTCGGCGACAAGCCGCTGGTGGCGGACATGTCCTCGACGCTGCTGTCGCGGCCGATCGACGTCAGCCGCTACGG
GCTGATCTACGCCGGGGCGCAGAAGAACATCGGCCCGGCCGGCGTGACCCTGGTGATCGTCCGCGAGGACCTGCTCGGCG
AGGCGATGCCGCAGACGCCCACGGTCTGGGACTACCAGCAGCAGGTCGACGCCGACTCCATGCTCAACACCCCCGCTACG
TATCCGCTCTACATCGCCGGGCTGGTGTTCCAGTGGCTGAAGGACCTCGGCGGTCTCGAGGCCATGGCCGAGATCAACCA
CCGCAAGGCGCAGAAGCTCTACGACGCTATCGACGCCTCGCCGTTCTACTCGAACCCGGTGGATCCGCAGGCGCGCTCGT
GGATGAACGTGCCCTTTGTCCTGGCCGATGACGGCCTCGACAAGCTCTTCCTCGAGGAGGCCGAGGCCGCCGGTCTGACC
ACGCTCAAGGGGCACCGCTCGGTGGGTGGCATGCGGGCCTCAATCTACAATGCCATGCCGGAGGCCGGCGTGGACCGGCT
CGTCGAGTTCATGGCCGATTTCGAGAGGCGAAACGGGTGA

Upstream 100 bases:

>100_bases
GGCGCCGGATGCGCCCGAGATGTAGGCAGTCAGGGGTCGACGGCCGGCGGTGTCGCTGCCGGGGCCCGGGTATTCGTGTT
TCGCAACCGAGGATCACCGC

Downstream 100 bases:

>100_bases
ATCCCATGTACCGCATCCTCACGCTGAACAACATCTCGGTGAAGGGCCTGGATCGGCTGCCGCGCGAACGCTTCGAGACC
TCCTCGGACATCGCGCACCC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSRVFNFSAGPAMLPEAVMRQAAEEMLDWQGTGMSVMEMSHRGKAYVSIAEKAEADLRALLQIPDNYKVLFLQGGATGQF
SAIPMNLLRGGKRADYIYTGQWSKKAIAEAKKFCEVNVAASGEPDMMHVPPQSQWQLSDDAAYVHFTPNETISGVEFHWL
PDVGDKPLVADMSSTLLSRPIDVSRYGLIYAGAQKNIGPAGVTLVIVREDLLGEAMPQTPTVWDYQQQVDADSMLNTPAT
YPLYIAGLVFQWLKDLGGLEAMAEINHRKAQKLYDAIDASPFYSNPVDPQARSWMNVPFVLADDGLDKLFLEEAEAAGLT
TLKGHRSVGGMRASIYNAMPEAGVDRLVEFMADFERRNG

Sequences:

>Translated_359_residues
MSRVFNFSAGPAMLPEAVMRQAAEEMLDWQGTGMSVMEMSHRGKAYVSIAEKAEADLRALLQIPDNYKVLFLQGGATGQF
SAIPMNLLRGGKRADYIYTGQWSKKAIAEAKKFCEVNVAASGEPDMMHVPPQSQWQLSDDAAYVHFTPNETISGVEFHWL
PDVGDKPLVADMSSTLLSRPIDVSRYGLIYAGAQKNIGPAGVTLVIVREDLLGEAMPQTPTVWDYQQQVDADSMLNTPAT
YPLYIAGLVFQWLKDLGGLEAMAEINHRKAQKLYDAIDASPFYSNPVDPQARSWMNVPFVLADDGLDKLFLEEAEAAGLT
TLKGHRSVGGMRASIYNAMPEAGVDRLVEFMADFERRNG
>Mature_358_residues
SRVFNFSAGPAMLPEAVMRQAAEEMLDWQGTGMSVMEMSHRGKAYVSIAEKAEADLRALLQIPDNYKVLFLQGGATGQFS
AIPMNLLRGGKRADYIYTGQWSKKAIAEAKKFCEVNVAASGEPDMMHVPPQSQWQLSDDAAYVHFTPNETISGVEFHWLP
DVGDKPLVADMSSTLLSRPIDVSRYGLIYAGAQKNIGPAGVTLVIVREDLLGEAMPQTPTVWDYQQQVDADSMLNTPATY
PLYIAGLVFQWLKDLGGLEAMAEINHRKAQKLYDAIDASPFYSNPVDPQARSWMNVPFVLADDGLDKLFLEEAEAAGLTT
LKGHRSVGGMRASIYNAMPEAGVDRLVEFMADFERRNG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=359, Percent_Identity=49.3036211699164, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI10863955, Length=354, Percent_Identity=43.2203389830509, Blast_Score=308, Evalue=7e-84,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=58.5635359116022, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=43.0555555555556, Blast_Score=310, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6324758, Length=385, Percent_Identity=43.1168831168831, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=49.0304709141274, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39535; Mature: 39404

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVFNFSAGPAMLPEAVMRQAAEEMLDWQGTGMSVMEMSHRGKAYVSIAEKAEADLRAL
CCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHH
LQIPDNYKVLFLQGGATGQFSAIPMNLLRGGKRADYIYTGQWSKKAIAEAKKFCEVNVAA
HCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHEEEEEEC
SGEPDMMHVPPQSQWQLSDDAAYVHFTPNETISGVEFHWLPDVGDKPLVADMSSTLLSRP
CCCCCEEECCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
IDVSRYGLIYAGAQKNIGPAGVTLVIVREDLLGEAMPQTPTVWDYQQQVDADSMLNTPAT
CCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCHHHHCCHHHHHCCCCC
YPLYIAGLVFQWLKDLGGLEAMAEINHRKAQKLYDAIDASPFYSNPVDPQARSWMNVPFV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEE
LADDGLDKLFLEEAEAAGLTTLKGHRSVGGMRASIYNAMPEAGVDRLVEFMADFERRNG
EECCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRVFNFSAGPAMLPEAVMRQAAEEMLDWQGTGMSVMEMSHRGKAYVSIAEKAEADLRAL
CCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHH
LQIPDNYKVLFLQGGATGQFSAIPMNLLRGGKRADYIYTGQWSKKAIAEAKKFCEVNVAA
HCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHHHHHHHEEEEEEC
SGEPDMMHVPPQSQWQLSDDAAYVHFTPNETISGVEFHWLPDVGDKPLVADMSSTLLSRP
CCCCCEEECCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
IDVSRYGLIYAGAQKNIGPAGVTLVIVREDLLGEAMPQTPTVWDYQQQVDADSMLNTPAT
CCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCHHHHCCHHHHHCCCCC
YPLYIAGLVFQWLKDLGGLEAMAEINHRKAQKLYDAIDASPFYSNPVDPQARSWMNVPFV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEE
LADDGLDKLFLEEAEAAGLTTLKGHRSVGGMRASIYNAMPEAGVDRLVEFMADFERRNG
EECCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA