Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 121997369

GI number: 121997369

Start: 642859

End: 643947

Strand: Reverse

Name: pheA [H]

Synonym: Hhal_0568

Alternate gene names: 121997369

Gene position: 643947-642859 (Counterclockwise)

Preceding gene: 121997370

Following gene: 121997368

Centisome position: 24.04

GC content: 69.97

Gene sequence:

>1089_bases
ATGTCCGTCGACAATGACGACCTCGCCGCGCTGCGGCAACGGATCGACGGGATCGACGACCAGATCCTCGAGCTGGTCAG
TGAGCGGGCCCGCCTGGCCGAGGAGGTGGCCCGCGCCAAGGCCCGCCGCGGCGAGGCGCTCAAGGTCTACCGCCCGGAGC
GCGAGGCGGAGATCCTGCGCCGGTTGACCGAGCACAACCGTGGGCCGCTGACCCGTGAGCAGGTCACGGTGCTCTTCCGC
GAGGTGATGTCCGCCTGCCGGGCGCTCCAGCAGCCGCTGACCGTCGCCTTTCTCGGCCCCCAGGGGACCTTCACCGAAGA
GGCGGCCAGCAAGCACTTCGGCCACGATGCCGGGATGTCGCCCCAGGCCACCATCGGCGGGGTCTTCCGCGAGGTGGAGT
CGGGCGCGGCGCACTACGGGGTGGTGCCGGTGGAGAACTCCTCCGAGGGCGTCGTCAGTCATACCCTGGATCGCTTCCTG
GATTCGGAGCTGGCCATCGTCGGTGAGGTGGAGCTACGCATCCACCACGCCCTGGCCAGTCACGCCGGGGGGCTGACCTC
GATTGACCGGGTCTACTCCCACCAGCAGGGGCTGTCGCAGTGCCGCGCGTGGCTGGAGACCCACCTCCCGCAGGCCGAGC
GCCACCCGGTCTCCAGCACGGCCGAAGCGGCCCGGCTGGCGGCCCTGGAGCCGAGCGCGGCGGCCATCGCCAGCGAGGCG
GCCGCGGAGCGCTACGGCGTGCCGCTGCTTCAGGAGCGCATCGAGGACTACCACGGCAACACCACCCGTTTTCTGGTTCT
GGGCTACCAGTCCCCGCCGCCCAGCGGCCACGACAAGACCTCGCTGGTGGTCTCCAGCGCCAACCGCTCCGGGTTGCTCT
TTCAGCTGCTCGAGCCGCTGGCGCGCAACGGCATCGACATGACCCGGATCGAGTCGCGTCCGGCACGCCAGCGCGGGGTT
TGGGAGTACGTCTTCTTCATCGATATCCTCGGGCACGCCGAGGACGAGAGCCTGCGCGGTCCCCTTGCGGAGATGCGCGA
GCGTGCCAGCCTCTTCCGTATCCTCGGCTCCTATCCAAGGGCGATCTGA

Upstream 100 bases:

>100_bases
CCTGGTGGATGTCGAGGGGCAGGTTCCCGACGCGGTGGCCGAGGAACTGCGCGCCATCGAGGGGGTTCTGAAGGTCCGCG
TGATCAGCTGAGGGGGAGCG

Downstream 100 bases:

>100_bases
TCCATGGCTGTACCCGAACCCCCGTTCCTCGAACAGGCCAACCCGGGCGTACGCGGGCTCGCTCCCTACGAGCCGGGCAA
GCCCATCGAGGCGCTGCGCC

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSVDNDDLAALRQRIDGIDDQILELVSERARLAEEVARAKARRGEALKVYRPEREAEILRRLTEHNRGPLTREQVTVLFR
EVMSACRALQQPLTVAFLGPQGTFTEEAASKHFGHDAGMSPQATIGGVFREVESGAAHYGVVPVENSSEGVVSHTLDRFL
DSELAIVGEVELRIHHALASHAGGLTSIDRVYSHQQGLSQCRAWLETHLPQAERHPVSSTAEAARLAALEPSAAAIASEA
AAERYGVPLLQERIEDYHGNTTRFLVLGYQSPPPSGHDKTSLVVSSANRSGLLFQLLEPLARNGIDMTRIESRPARQRGV
WEYVFFIDILGHAEDESLRGPLAEMRERASLFRILGSYPRAI

Sequences:

>Translated_362_residues
MSVDNDDLAALRQRIDGIDDQILELVSERARLAEEVARAKARRGEALKVYRPEREAEILRRLTEHNRGPLTREQVTVLFR
EVMSACRALQQPLTVAFLGPQGTFTEEAASKHFGHDAGMSPQATIGGVFREVESGAAHYGVVPVENSSEGVVSHTLDRFL
DSELAIVGEVELRIHHALASHAGGLTSIDRVYSHQQGLSQCRAWLETHLPQAERHPVSSTAEAARLAALEPSAAAIASEA
AAERYGVPLLQERIEDYHGNTTRFLVLGYQSPPPSGHDKTSLVVSSANRSGLLFQLLEPLARNGIDMTRIESRPARQRGV
WEYVFFIDILGHAEDESLRGPLAEMRERASLFRILGSYPRAI
>Mature_361_residues
SVDNDDLAALRQRIDGIDDQILELVSERARLAEEVARAKARRGEALKVYRPEREAEILRRLTEHNRGPLTREQVTVLFRE
VMSACRALQQPLTVAFLGPQGTFTEEAASKHFGHDAGMSPQATIGGVFREVESGAAHYGVVPVENSSEGVVSHTLDRFLD
SELAIVGEVELRIHHALASHAGGLTSIDRVYSHQQGLSQCRAWLETHLPQAERHPVSSTAEAARLAALEPSAAAIASEAA
AERYGVPLLQERIEDYHGNTTRFLVLGYQSPPPSGHDKTSLVVSSANRSGLLFQLLEPLARNGIDMTRIESRPARQRGVW
EYVFFIDILGHAEDESLRGPLAEMRERASLFRILGSYPRAI

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=383, Percent_Identity=33.9425587467363, Blast_Score=174, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6324013, Length=355, Percent_Identity=25.9154929577465, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39932; Mature: 39801

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDNDDLAALRQRIDGIDDQILELVSERARLAEEVARAKARRGEALKVYRPEREAEILR
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RLTEHNRGPLTREQVTVLFREVMSACRALQQPLTVAFLGPQGTFTEEAASKHFGHDAGMS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCC
PQATIGGVFREVESGAAHYGVVPVENSSEGVVSHTLDRFLDSELAIVGEVELRIHHALAS
CCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
HAGGLTSIDRVYSHQQGLSQCRAWLETHLPQAERHPVSSTAEAARLAALEPSAAAIASEA
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
AAERYGVPLLQERIEDYHGNTTRFLVLGYQSPPPSGHDKTSLVVSSANRSGLLFQLLEPL
HHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
ARNGIDMTRIESRPARQRGVWEYVFFIDILGHAEDESLRGPLAEMRERASLFRILGSYPR
HHCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCC
AI
CC
>Mature Secondary Structure 
SVDNDDLAALRQRIDGIDDQILELVSERARLAEEVARAKARRGEALKVYRPEREAEILR
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RLTEHNRGPLTREQVTVLFREVMSACRALQQPLTVAFLGPQGTFTEEAASKHFGHDAGMS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCC
PQATIGGVFREVESGAAHYGVVPVENSSEGVVSHTLDRFLDSELAIVGEVELRIHHALAS
CCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
HAGGLTSIDRVYSHQQGLSQCRAWLETHLPQAERHPVSSTAEAARLAALEPSAAAIASEA
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
AAERYGVPLLQERIEDYHGNTTRFLVLGYQSPPPSGHDKTSLVVSSANRSGLLFQLLEPL
HHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
ARNGIDMTRIESRPARQRGVWEYVFFIDILGHAEDESLRGPLAEMRERASLFRILGSYPR
HHCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCC
AI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]