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The map label for this gene is hisC2 [H]

Identifier: 121997368

GI number: 121997368

Start: 641710

End: 642855

Strand: Reverse

Name: hisC2 [H]

Synonym: Hhal_0567

Alternate gene names: 121997368

Gene position: 642855-641710 (Counterclockwise)

Preceding gene: 121997369

Following gene: 121997367

Centisome position: 24.0

GC content: 72.34

Gene sequence:

>1146_bases
ATGGCTGTACCCGAACCCCCGTTCCTCGAACAGGCCAACCCGGGCGTACGCGGGCTCGCTCCCTACGAGCCGGGCAAGCC
CATCGAGGCGCTGCGCCGCGAGTACGGTGTCGAGGAGGTGATCAAACTCGCCTCCAACGAGAATCCGCTGGGGCCCTCGC
CCCGGGCATCCGAGGCCGCTGCCGCGGCGGTGCAGGAAGGCCACCGCTATCCCGACGGCAACGGCTTCGAGCTTCGCCAC
GCCATCGCCGAGCGCCACGGCATCGACCCGCAGCGGGTCACCCTGGGCAACGGCTCCAACGATGTCCTCGCCCTGGTGGC
CCAGACCTTCCTCGGTCCCGGGCGGTGCGCGGTGTTCTCGGCGCACGCCTTCGCCGTCTATCCGATCGTGACCCAGGCCG
TGGGGGCCGAGGCGCGGGTGGTGCCGGCGCTCGCTGCCGATCACCCGGCGCAGCCCCGCGGCCACGACCTGGAGGCCATG
GCGGCGGCGACCGACGATACGGTCCAGGTGGTCTTCGTCGCCAATCCCAACAACCCCACCGGCACCTGGGTCGGGGCCGA
GGCCCTGCGTCGCTTCCTCGACGCCGTGCCGGCGCGGACCCTGGCCGTGGTCGACGAGGCGTACTTCGAGTACGCGGTGG
AGGAGGCCGACTATCCGGACGCCAGCCGCTGGCTCGACGACTACCCGAATCTGATCGTCACCCGCAGCTTCTCGAAGGTC
CACGGCCTGGGCGGGCTGCGGGCCGGGTACGCCCTGTCGCACCCGGCGGTGGCCGAGCTGATGAACCGGGTCCGTCAGCC
CTTCAACTGCTCGGGTCCGGCGCAGGCCGCGGCGGCGGCGTCGTTGGCCGATGCCGAGCACCTGGAGCGCTCGGTGGCGC
TGAACACCGAGCAGCGTGCACTGCTGCGCCGCGGGCTGGAGGAGCTGGGCTTTGTCCCCCTGCCGTCCGCCGGCAACTTC
CTGACCTTCGACGCCGGGGCGCGGGCTGCCGAGCTCAACGAGGGGCTGCTGCGCAGCGGCGTTATCGTCCGCCCGGTGGA
CGCCTACGACCTGCCCGGACACCTGCGGGTGAGCGTCGGCACGCCGACGGAGAACCGCACCTTCCTGGCCGCGCTGTCCC
GGCAGCTGCATGGAGGCGCGGCGTGA

Upstream 100 bases:

>100_bases
GCACGCCGAGGACGAGAGCCTGCGCGGTCCCCTTGCGGAGATGCGCGAGCGTGCCAGCCTCTTCCGTATCCTCGGCTCCT
ATCCAAGGGCGATCTGATCC

Downstream 100 bases:

>100_bases
TCCGGCGTCTGGCCATCATCGGCGTCGGCCTGATCGGCGGCTCGCTGGCCCTGTCGCTGCGCCGCAGCGGGGCGGTCGAG
GAGGTGATCGGCTGCGGGCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAVPEPPFLEQANPGVRGLAPYEPGKPIEALRREYGVEEVIKLASNENPLGPSPRASEAAAAAVQEGHRYPDGNGFELRH
AIAERHGIDPQRVTLGNGSNDVLALVAQTFLGPGRCAVFSAHAFAVYPIVTQAVGAEARVVPALAADHPAQPRGHDLEAM
AAATDDTVQVVFVANPNNPTGTWVGAEALRRFLDAVPARTLAVVDEAYFEYAVEEADYPDASRWLDDYPNLIVTRSFSKV
HGLGGLRAGYALSHPAVAELMNRVRQPFNCSGPAQAAAAASLADAEHLERSVALNTEQRALLRRGLEELGFVPLPSAGNF
LTFDAGARAAELNEGLLRSGVIVRPVDAYDLPGHLRVSVGTPTENRTFLAALSRQLHGGAA

Sequences:

>Translated_381_residues
MAVPEPPFLEQANPGVRGLAPYEPGKPIEALRREYGVEEVIKLASNENPLGPSPRASEAAAAAVQEGHRYPDGNGFELRH
AIAERHGIDPQRVTLGNGSNDVLALVAQTFLGPGRCAVFSAHAFAVYPIVTQAVGAEARVVPALAADHPAQPRGHDLEAM
AAATDDTVQVVFVANPNNPTGTWVGAEALRRFLDAVPARTLAVVDEAYFEYAVEEADYPDASRWLDDYPNLIVTRSFSKV
HGLGGLRAGYALSHPAVAELMNRVRQPFNCSGPAQAAAAASLADAEHLERSVALNTEQRALLRRGLEELGFVPLPSAGNF
LTFDAGARAAELNEGLLRSGVIVRPVDAYDLPGHLRVSVGTPTENRTFLAALSRQLHGGAA
>Mature_380_residues
AVPEPPFLEQANPGVRGLAPYEPGKPIEALRREYGVEEVIKLASNENPLGPSPRASEAAAAAVQEGHRYPDGNGFELRHA
IAERHGIDPQRVTLGNGSNDVLALVAQTFLGPGRCAVFSAHAFAVYPIVTQAVGAEARVVPALAADHPAQPRGHDLEAMA
AATDDTVQVVFVANPNNPTGTWVGAEALRRFLDAVPARTLAVVDEAYFEYAVEEADYPDASRWLDDYPNLIVTRSFSKVH
GLGGLRAGYALSHPAVAELMNRVRQPFNCSGPAQAAAAASLADAEHLERSVALNTEQRALLRRGLEELGFVPLPSAGNFL
TFDAGARAAELNEGLLRSGVIVRPVDAYDLPGHLRVSVGTPTENRTFLAALSRQLHGGAA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=369, Percent_Identity=28.4552845528455, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322075, Length=392, Percent_Identity=24.7448979591837, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40472; Mature: 40341

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPEPPFLEQANPGVRGLAPYEPGKPIEALRREYGVEEVIKLASNENPLGPSPRASEAA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHH
AAAVQEGHRYPDGNGFELRHAIAERHGIDPQRVTLGNGSNDVLALVAQTFLGPGRCAVFS
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEE
AHAFAVYPIVTQAVGAEARVVPALAADHPAQPRGHDLEAMAAATDDTVQVVFVANPNNPT
CCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCC
GTWVGAEALRRFLDAVPARTLAVVDEAYFEYAVEEADYPDASRWLDDYPNLIVTRSFSKV
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCHHHH
HGLGGLRAGYALSHPAVAELMNRVRQPFNCSGPAQAAAAASLADAEHLERSVALNTEQRA
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LLRRGLEELGFVPLPSAGNFLTFDAGARAAELNEGLLRSGVIVRPVDAYDLPGHLRVSVG
HHHHHHHHCCCEECCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEC
TPTENRTFLAALSRQLHGGAA
CCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVPEPPFLEQANPGVRGLAPYEPGKPIEALRREYGVEEVIKLASNENPLGPSPRASEAA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHH
AAAVQEGHRYPDGNGFELRHAIAERHGIDPQRVTLGNGSNDVLALVAQTFLGPGRCAVFS
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEE
AHAFAVYPIVTQAVGAEARVVPALAADHPAQPRGHDLEAMAAATDDTVQVVFVANPNNPT
CCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCC
GTWVGAEALRRFLDAVPARTLAVVDEAYFEYAVEEADYPDASRWLDDYPNLIVTRSFSKV
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCHHHH
HGLGGLRAGYALSHPAVAELMNRVRQPFNCSGPAQAAAAASLADAEHLERSVALNTEQRA
HCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LLRRGLEELGFVPLPSAGNFLTFDAGARAAELNEGLLRSGVIVRPVDAYDLPGHLRVSVG
HHHHHHHHCCCEECCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEC
TPTENRTFLAALSRQLHGGAA
CCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA