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The map label for this gene is ybdL [H]

Identifier: 121611826

GI number: 121611826

Start: 5447079

End: 5448260

Strand: Direct

Name: ybdL [H]

Synonym: Veis_4927

Alternate gene names: 121611826

Gene position: 5447079-5448260 (Clockwise)

Preceding gene: 121611825

Following gene: 121611829

Centisome position: 97.85

GC content: 65.65

Gene sequence:

>1182_bases
ATGACTGAAGCCACCCAAGCCAGCCCGACCGCCCGCACACCGGCCTTGCCGAACAAGCTGCCGCAGGTGGGCACCACCAT
CTTCACCGTCATGTCGGCCTTGGCCGCCGAGCACGACGCCGTCAACCTGGGCCAGGGCTTTCCTGACTTTGCCTGCGACC
CCGCTTTGCTGGACACCGTGACCGAGGCCATGCGGGCGGGCCACAACCAATACCCGCCGATGCCCGGCATCCGCCCATTG
CGCGCCGCAGTAGCGGCCAAGATCGAGGCACTCCATGGCCGCCAGTACGACGCCGACACCGAGATCACCATCACTGCGGG
TGCAACGCAGGCCATCATCACCGCCATCCTGGCCTGCGTGCACCCCGGCGACGAAGTCATCGTGCTCGACCCCTGCTATG
ACAGCTATGTGCCCAATATCGTCCTGGCCGGCGGCCGCGCCGTGCGCGTGCCCCTGACGCCCGGCAGTTTCCGCCCGGAC
TTCGCCAGAATCGGCGCCGCCATCACGGCGCGCACGCGCGCGCTCATCATCAACAGCCCGCACAACCCCAGCGCCACCAT
CTGGAGCGCTGCCGAAATGCGCCAACTGCAAGCGCTGTTGGCGCCCACCGACATCCTGCTGATCAGCGATGAGGTGTACG
AGCACATGGTGTTCGACGGCGCCGAGCACCAGAGCGCAGCGCGCTTTGCGGGCTTGGCGGCACGCGCGTTCATCGTGTCG
AGCTTTGGCAAGACCTTCCACGTCACCGGCTGGAAGGTCGGCACCATGGCCGCCCCCGCCGCTTTGACGGCCGAATTCCG
CAAGGTGCACCAGTTCAACGTGTTCACCGTCAACACCCCGATGCAGCATGGCCTGGCGAGCTACCTGAAAGACCCCGCAC
CCTACCTGCGACTGCCCGCTTTCTACCAGGCCAAGCGCGACCTCTTTCGCCAAGGACTGGCAGACACACGCCTGAAACTG
CTGCCCAGCGCGGGCAGTTATTTTCAGTGCGTCGACATCTCCTCCGTGAGCGCACTGAACGAATCCGACTTCTGCCAATG
GCTCACGCGCGAAGTGGGGGTGGCCGCGATCCCGCTGTCGGCGTTCTATGGCGACGGGTTCGATCAGCGCGTGGTGCGCC
TGTGCTTTGCGAAAAAGGACGAGACGCTGCGAGCGGCATTGGAGCGGCTGCGCAAGCTGTGA

Upstream 100 bases:

>100_bases
CCGAACTGATCAGTGAGCGCCTGAGCCGCGAACTCATCGCCCAGGCGATGAGCGGGCAGGCCAATGACTACGAACTCTGA
CTTCCACGCCGCCACGCCCC

Downstream 100 bases:

>100_bases
CAGCGCCCGGGTTCGGCAACAAGTCCAGACAAGGCCCCGTCTTTTGGAAAACCCATTTCAGGGCACAATTGCGGGGATCG
ACCACCCTGTCATCGTTGAC

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEATQASPTARTPALPNKLPQVGTTIFTVMSALAAEHDAVNLGQGFPDFACDPALLDTVTEAMRAGHNQYPPMPGIRPL
RAAVAAKIEALHGRQYDADTEITITAGATQAIITAILACVHPGDEVIVLDPCYDSYVPNIVLAGGRAVRVPLTPGSFRPD
FARIGAAITARTRALIINSPHNPSATIWSAAEMRQLQALLAPTDILLISDEVYEHMVFDGAEHQSAARFAGLAARAFIVS
SFGKTFHVTGWKVGTMAAPAALTAEFRKVHQFNVFTVNTPMQHGLASYLKDPAPYLRLPAFYQAKRDLFRQGLADTRLKL
LPSAGSYFQCVDISSVSALNESDFCQWLTREVGVAAIPLSAFYGDGFDQRVVRLCFAKKDETLRAALERLRKL

Sequences:

>Translated_393_residues
MTEATQASPTARTPALPNKLPQVGTTIFTVMSALAAEHDAVNLGQGFPDFACDPALLDTVTEAMRAGHNQYPPMPGIRPL
RAAVAAKIEALHGRQYDADTEITITAGATQAIITAILACVHPGDEVIVLDPCYDSYVPNIVLAGGRAVRVPLTPGSFRPD
FARIGAAITARTRALIINSPHNPSATIWSAAEMRQLQALLAPTDILLISDEVYEHMVFDGAEHQSAARFAGLAARAFIVS
SFGKTFHVTGWKVGTMAAPAALTAEFRKVHQFNVFTVNTPMQHGLASYLKDPAPYLRLPAFYQAKRDLFRQGLADTRLKL
LPSAGSYFQCVDISSVSALNESDFCQWLTREVGVAAIPLSAFYGDGFDQRVVRLCFAKKDETLRAALERLRKL
>Mature_392_residues
TEATQASPTARTPALPNKLPQVGTTIFTVMSALAAEHDAVNLGQGFPDFACDPALLDTVTEAMRAGHNQYPPMPGIRPLR
AAVAAKIEALHGRQYDADTEITITAGATQAIITAILACVHPGDEVIVLDPCYDSYVPNIVLAGGRAVRVPLTPGSFRPDF
ARIGAAITARTRALIINSPHNPSATIWSAAEMRQLQALLAPTDILLISDEVYEHMVFDGAEHQSAARFAGLAARAFIVSS
FGKTFHVTGWKVGTMAAPAALTAEFRKVHQFNVFTVNTPMQHGLASYLKDPAPYLRLPAFYQAKRDLFRQGLADTRLKLL
PSAGSYFQCVDISSVSALNESDFCQWLTREVGVAAIPLSAFYGDGFDQRVVRLCFAKKDETLRAALERLRKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=35.1898734177215, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=35.1898734177215, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI56713254, Length=405, Percent_Identity=32.3456790123457, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI56713256, Length=404, Percent_Identity=32.4257425742574, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=31.8066157760814, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4507369, Length=215, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=53.125, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1788722, Length=369, Percent_Identity=23.8482384823848, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788627, Length=258, Percent_Identity=27.5193798449612, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=35.4368932038835, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=35.4368932038835, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17567369, Length=407, Percent_Identity=32.6781326781327, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17567663, Length=351, Percent_Identity=24.7863247863248, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=30.7692307692308, Blast_Score=179, Evalue=7e-46,
Organism=Drosophila melanogaster, GI28573069, Length=410, Percent_Identity=32.6829268292683, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24646114, Length=410, Percent_Identity=32.6829268292683, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI28573067, Length=410, Percent_Identity=32.6829268292683, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI28573065, Length=410, Percent_Identity=32.6829268292683, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI18859735, Length=208, Percent_Identity=29.8076923076923, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42552; Mature: 42421

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATQASPTARTPALPNKLPQVGTTIFTVMSALAAEHDAVNLGQGFPDFACDPALLDTV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
TEAMRAGHNQYPPMPGIRPLRAAVAAKIEALHGRQYDADTEITITAGATQAIITAILACV
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHC
HPGDEVIVLDPCYDSYVPNIVLAGGRAVRVPLTPGSFRPDFARIGAAITARTRALIINSP
CCCCCEEEECCCHHHHCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHEECEEEEEEECC
HNPSATIWSAAEMRQLQALLAPTDILLISDEVYEHMVFDGAEHQSAARFAGLAARAFIVS
CCCCCHHCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SFGKTFHVTGWKVGTMAAPAALTAEFRKVHQFNVFTVNTPMQHGLASYLKDPAPYLRLPA
HCCCEEEECCEEECCHHCCHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCHHCCCH
FYQAKRDLFRQGLADTRLKLLPSAGSYFQCVDISSVSALNESDFCQWLTREVGVAAIPLS
HHHHHHHHHHCCHHHHHHHEECCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCCEEEEHH
AFYGDGFDQRVVRLCFAKKDETLRAALERLRKL
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TEATQASPTARTPALPNKLPQVGTTIFTVMSALAAEHDAVNLGQGFPDFACDPALLDTV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
TEAMRAGHNQYPPMPGIRPLRAAVAAKIEALHGRQYDADTEITITAGATQAIITAILACV
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHC
HPGDEVIVLDPCYDSYVPNIVLAGGRAVRVPLTPGSFRPDFARIGAAITARTRALIINSP
CCCCCEEEECCCHHHHCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHEECEEEEEEECC
HNPSATIWSAAEMRQLQALLAPTDILLISDEVYEHMVFDGAEHQSAARFAGLAARAFIVS
CCCCCHHCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SFGKTFHVTGWKVGTMAAPAALTAEFRKVHQFNVFTVNTPMQHGLASYLKDPAPYLRLPA
HCCCEEEECCEEECCHHCCHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCHHCCCH
FYQAKRDLFRQGLADTRLKLLPSAGSYFQCVDISSVSALNESDFCQWLTREVGVAAIPLS
HHHHHHHHHHCCHHHHHHHEECCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCCEEEEHH
AFYGDGFDQRVVRLCFAKKDETLRAALERLRKL
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]