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The map label for this gene is tolQ [H]

Identifier: 121611697

GI number: 121611697

Start: 5293814

End: 5294521

Strand: Direct

Name: tolQ [H]

Synonym: Veis_4794

Alternate gene names: 121611697

Gene position: 5293814-5294521 (Clockwise)

Preceding gene: 121611696

Following gene: 121611698

Centisome position: 95.1

GC content: 65.54

Gene sequence:

>708_bases
ATGAACTCCCAAGACATGTCCATCATCTCCCTGATGCTGCACGCCAGTTGGATGGTGCAACTCGTGCTGCTGCTGCTGCT
GAGCGTGTCGATCGCCAGTTGGGCGGCGATCTTGCGCAAGCTGTTTGCGCTGGCGCGCATCAAAGCCCTGAACGAGGAAT
TCGAGCGCGAATTCTGGTCCGGCGCCAGCCTGAACGACCTGTACGCCAACGCCACCCGCAACGCCAGACAGGCCGGCCCG
ATGGAGCGCATCTTTGCCAGCGGCATGCGCGAGCACCAAAAACTGCGCGAGCGCCGCATCGCCGACCCCGGCACCCTGCT
CGACGGCGCGCGCCGCGCGATGCGCGCGAGCTTTCAGCGCGAGATGGATGTGGTCGAATCCAGCCTGTCGTTCCTGGCCT
CGGTAGGCTCGGTGTCGCCGTATGTGGGCCTGTTTGGCACGGTGTGGGGCATCATGCACGCCTTCACCGGCTTTGCCGGC
ATGGCGCAGGTGACGCTGGCCACGGTGGCCCCCGGCATTGCCGAAGCCCTGGTGGCCACGGCCATCGGCCTGTTTGCCGC
GATTCCGGCGGTGATCGCCTACAACCGCTTTGCACGCGACATCGACCGCGTGGCCACGCACCAGGAGACCTTCATCGAGG
AGTTCTCCAACATCCTGCAACGCAATCTGGGCGCCCATGTCGCCCATGCCGCAGCCCCGGGCCACTGA

Upstream 100 bases:

>100_bases
AGCGAGACCCGAGCCGCCCGGGCCGGATGCGCTGCGCATCGGCCCGGGCCACGTTGCGCCCTGCAAGAATCGCCAGCACC
TCTTTTTTGAAACGACGCCG

Downstream 100 bases:

>100_bases
GCACAGGAAAACCGCCGCCATGCCTGCCATCGCCACCCGCGGCCGAGGCCGCCGTACCATCAACGAGATCAACATGGTGC
CGTTCATCGACGTGATGCTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNSQDMSIISLMLHASWMVQLVLLLLLSVSIASWAAILRKLFALARIKALNEEFEREFWSGASLNDLYANATRNARQAGP
MERIFASGMREHQKLRERRIADPGTLLDGARRAMRASFQREMDVVESSLSFLASVGSVSPYVGLFGTVWGIMHAFTGFAG
MAQVTLATVAPGIAEALVATAIGLFAAIPAVIAYNRFARDIDRVATHQETFIEEFSNILQRNLGAHVAHAAAPGH

Sequences:

>Translated_235_residues
MNSQDMSIISLMLHASWMVQLVLLLLLSVSIASWAAILRKLFALARIKALNEEFEREFWSGASLNDLYANATRNARQAGP
MERIFASGMREHQKLRERRIADPGTLLDGARRAMRASFQREMDVVESSLSFLASVGSVSPYVGLFGTVWGIMHAFTGFAG
MAQVTLATVAPGIAEALVATAIGLFAAIPAVIAYNRFARDIDRVATHQETFIEEFSNILQRNLGAHVAHAAAPGH
>Mature_235_residues
MNSQDMSIISLMLHASWMVQLVLLLLLSVSIASWAAILRKLFALARIKALNEEFEREFWSGASLNDLYANATRNARQAGP
MERIFASGMREHQKLRERRIADPGTLLDGARRAMRASFQREMDVVESSLSFLASVGSVSPYVGLFGTVWGIMHAFTGFAG
MAQVTLATVAPGIAEALVATAIGLFAAIPAVIAYNRFARDIDRVATHQETFIEEFSNILQRNLGAHVAHAAAPGH

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=217, Percent_Identity=47.926267281106, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1789381, Length=205, Percent_Identity=37.0731707317073, Blast_Score=110, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQDMSIISLMLHASWMVQLVLLLLLSVSIASWAAILRKLFALARIKALNEEFEREFWS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GASLNDLYANATRNARQAGPMERIFASGMREHQKLRERRIADPGTLLDGARRAMRASFQR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EMDVVESSLSFLASVGSVSPYVGLFGTVWGIMHAFTGFAGMAQVTLATVAPGIAEALVAT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLFAAIPAVIAYNRFARDIDRVATHQETFIEEFSNILQRNLGAHVAHAAAPGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSQDMSIISLMLHASWMVQLVLLLLLSVSIASWAAILRKLFALARIKALNEEFEREFWS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GASLNDLYANATRNARQAGPMERIFASGMREHQKLRERRIADPGTLLDGARRAMRASFQR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EMDVVESSLSFLASVGSVSPYVGLFGTVWGIMHAFTGFAGMAQVTLATVAPGIAEALVAT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLFAAIPAVIAYNRFARDIDRVATHQETFIEEFSNILQRNLGAHVAHAAAPGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]