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The map label for this gene is pqqL [C]

Identifier: 121611666

GI number: 121611666

Start: 5256198

End: 5257637

Strand: Direct

Name: pqqL [C]

Synonym: Veis_4762

Alternate gene names: 121611666

Gene position: 5256198-5257637 (Clockwise)

Preceding gene: 121611664

Following gene: 121611667

Centisome position: 94.42

GC content: 69.86

Gene sequence:

>1440_bases
ATGAAACGCATTCCTACCCTCGCGGGCCTGCTGGTCGGCCTGTCTTTCGGGGCTGCCTTTGCGGCAACGCCACCGCCCTG
CCCTCCCACCCCGGCAGCCATCACCACGGCCTGTGGAGCGCAGCAGTTCACGCTGGCCAACGGCATGCAATTGATCGTGC
AGCCCGACCACCGCGCGCCGACGGCGGTGCACATGGTCTGGGTGCGGGTAGGCTCGATGGATGAGGTCGATGGCAGTTCG
GGCCTGGCCCATGCGCTCGAACACATGATGTTCAAAGGCTCCAAAACCGTGCCGCCGGGCGAATTCTCGCGCCGCGTGGC
GGCCCTGGGGGGGCGTGAAAACGCCTTCACCGCCCGCGACTACACCGGCTACTACCAGCAGATTCCGGCGCAGCACCTGC
AAGAGGTGATGCGGCTCGAAGCAGACCGCTTTGCCAACAACGACTGGCCCGACGCAGAGTTCCGCAAGGAGATCGAGGTC
GTCAAGGAAGAGCGCCGCCTGCGCACCGAAGACCAGCCCCGCGCCCTGCTGATCGAGCAGCTCTTTGCCGCCACCTTCAA
CGCCTCGCCCTACCGCCGCCCGGTCGTGGGCTGGATGAGCGACCTCGACGCGATGACGCCCGACGATGTGCGCGCCTTCC
ACCGCCAGTGGTACCAGCCCGGCAATGCCGCCGTGGTGGTGGTCGGCGATGTGGACGTGGCACAGGTGCGCGCGCTGGCC
GAAAAGTATTACGGCAGCCTGCCCGCCCACGCCCTGCCCGTGCGCAAGCCGCGCACCGAGCCGGCGCAGCCGGGCCTGCG
CCGCATCGCCGTGAAGGCGCCGGCCGAGCAGGCTTATGTGGCGCTGGCGTTTCGCGTGCCCGGCCTCGCGCGCTTGCAGA
ACCTGGACGAGGCCGACCATGACGCCCTGGCGCTGCAAATGCTGTCCGCCGTGCTCAGCGGCTACGACGGCGCCCGGCTC
GAACGGGCGCTGACCCAGGGCGCGCAGCCCGTGGCCGACAGCGCCAGCAGTTCTGCACTGGTCATCGGGCGCGGCCCGAG
CCTGTTCCTGCTCAGCGGCGTGCCCGCAGCCGGGCGGGCAGCGCAGCAGGTCGAAGACGCGCTGCGCGCCGAAGTCGCGC
GCGTGGCGCGCGACGGGGTGGGCCAGGCGGAACTGGACCGGGTCAAGACACAATGGATCGCCGCCAGCGTGTACCAGCGC
GACTCGATGATCAGCCAGGCGCAGGAACTGGGCAGCAACTGGGCGCAGGGATTTGCCCCAGACGCCCAGGAGCGCCTGCT
GGCCTTGCTGCGCAGCGTCACGCCAGAGCAGGTGCAGGCCGTGGCCGCCAGGTACTTTGGCGACGACCAACTCACCGTGG
CCACCTTGCTGCCGCAACCCCTGGCCCCACGCAAGCGCACTGCGCCCCTGTCGTCGCCCCACGACGCCGCCATCCGCTGA

Upstream 100 bases:

>100_bases
GCCGCCGCGCTGGCCGCAGCAGGTGCGTCGGCCGGCACGGGCGCGGGTTTTTTTTTGAAAAAACTGAACATTTGGCGGGC
TCTTGGAATCACTGCATTCT

Downstream 100 bases:

>100_bases
ACCCGCCCGGGATCACCCCATGCTCACCATCAAAAACATAGCTGCACGCGCATTGCTCATCGGCGCATCGACCCTCGTTC
ATTGCCATCCGGCCTGGGCG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKRIPTLAGLLVGLSFGAAFAATPPPCPPTPAAITTACGAQQFTLANGMQLIVQPDHRAPTAVHMVWVRVGSMDEVDGSS
GLAHALEHMMFKGSKTVPPGEFSRRVAALGGRENAFTARDYTGYYQQIPAQHLQEVMRLEADRFANNDWPDAEFRKEIEV
VKEERRLRTEDQPRALLIEQLFAATFNASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYQPGNAAVVVVGDVDVAQVRALA
EKYYGSLPAHALPVRKPRTEPAQPGLRRIAVKAPAEQAYVALAFRVPGLARLQNLDEADHDALALQMLSAVLSGYDGARL
ERALTQGAQPVADSASSSALVIGRGPSLFLLSGVPAAGRAAQQVEDALRAEVARVARDGVGQAELDRVKTQWIAASVYQR
DSMISQAQELGSNWAQGFAPDAQERLLALLRSVTPEQVQAVAARYFGDDQLTVATLLPQPLAPRKRTAPLSSPHDAAIR

Sequences:

>Translated_479_residues
MKRIPTLAGLLVGLSFGAAFAATPPPCPPTPAAITTACGAQQFTLANGMQLIVQPDHRAPTAVHMVWVRVGSMDEVDGSS
GLAHALEHMMFKGSKTVPPGEFSRRVAALGGRENAFTARDYTGYYQQIPAQHLQEVMRLEADRFANNDWPDAEFRKEIEV
VKEERRLRTEDQPRALLIEQLFAATFNASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYQPGNAAVVVVGDVDVAQVRALA
EKYYGSLPAHALPVRKPRTEPAQPGLRRIAVKAPAEQAYVALAFRVPGLARLQNLDEADHDALALQMLSAVLSGYDGARL
ERALTQGAQPVADSASSSALVIGRGPSLFLLSGVPAAGRAAQQVEDALRAEVARVARDGVGQAELDRVKTQWIAASVYQR
DSMISQAQELGSNWAQGFAPDAQERLLALLRSVTPEQVQAVAARYFGDDQLTVATLLPQPLAPRKRTAPLSSPHDAAIR
>Mature_479_residues
MKRIPTLAGLLVGLSFGAAFAATPPPCPPTPAAITTACGAQQFTLANGMQLIVQPDHRAPTAVHMVWVRVGSMDEVDGSS
GLAHALEHMMFKGSKTVPPGEFSRRVAALGGRENAFTARDYTGYYQQIPAQHLQEVMRLEADRFANNDWPDAEFRKEIEV
VKEERRLRTEDQPRALLIEQLFAATFNASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYQPGNAAVVVVGDVDVAQVRALA
EKYYGSLPAHALPVRKPRTEPAQPGLRRIAVKAPAEQAYVALAFRVPGLARLQNLDEADHDALALQMLSAVLSGYDGARL
ERALTQGAQPVADSASSSALVIGRGPSLFLLSGVPAAGRAAQQVEDALRAEVARVARDGVGQAELDRVKTQWIAASVYQR
DSMISQAQELGSNWAQGFAPDAQERLLALLRSVTPEQVQAVAARYFGDDQLTVATLLPQPLAPRKRTAPLSSPHDAAIR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=314, Percent_Identity=27.3885350318471, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI94538354, Length=208, Percent_Identity=24.5192307692308, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI155969707, Length=261, Percent_Identity=25.6704980842912, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787770, Length=385, Percent_Identity=27.7922077922078, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17553678, Length=281, Percent_Identity=27.4021352313167, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71999683, Length=228, Percent_Identity=24.5614035087719, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=216, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323421, Length=269, Percent_Identity=24.5353159851301, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357875, Length=215, Percent_Identity=26.5116279069767, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646943, Length=215, Percent_Identity=26.5116279069767, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51939; Mature: 51939

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIPTLAGLLVGLSFGAAFAATPPPCPPTPAAITTACGAQQFTLANGMQLIVQPDHRAP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHCCCEEEEECCCCCC
TAVHMVWVRVGSMDEVDGSSGLAHALEHMMFKGSKTVPPGEFSRRVAALGGRENAFTARD
HHHEEEEHEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
YTGYYQQIPAQHLQEVMRLEADRFANNDWPDAEFRKEIEVVKEERRLRTEDQPRALLIEQ
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LFAATFNASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYQPGNAAVVVVGDVDVAQVRALA
HHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EKYYGSLPAHALPVRKPRTEPAQPGLRRIAVKAPAEQAYVALAFRVPGLARLQNLDEADH
HHHHCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCHHHEEEEEECCCCHHHHHCCCCCHH
DALALQMLSAVLSGYDGARLERALTQGAQPVADSASSSALVIGRGPSLFLLSGVPAAGRA
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHH
AQQVEDALRAEVARVARDGVGQAELDRVKTQWIAASVYQRDSMISQAQELGSNWAQGFAP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAQERLLALLRSVTPEQVQAVAARYFGDDQLTVATLLPQPLAPRKRTAPLSSPHDAAIR
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRIPTLAGLLVGLSFGAAFAATPPPCPPTPAAITTACGAQQFTLANGMQLIVQPDHRAP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHCCCEEEEECCCCCC
TAVHMVWVRVGSMDEVDGSSGLAHALEHMMFKGSKTVPPGEFSRRVAALGGRENAFTARD
HHHEEEEHEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
YTGYYQQIPAQHLQEVMRLEADRFANNDWPDAEFRKEIEVVKEERRLRTEDQPRALLIEQ
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LFAATFNASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYQPGNAAVVVVGDVDVAQVRALA
HHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
EKYYGSLPAHALPVRKPRTEPAQPGLRRIAVKAPAEQAYVALAFRVPGLARLQNLDEADH
HHHHCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCHHHEEEEEECCCCHHHHHCCCCCHH
DALALQMLSAVLSGYDGARLERALTQGAQPVADSASSSALVIGRGPSLFLLSGVPAAGRA
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHH
AQQVEDALRAEVARVARDGVGQAELDRVKTQWIAASVYQRDSMISQAQELGSNWAQGFAP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAQERLLALLRSVTPEQVQAVAARYFGDDQLTVATLLPQPLAPRKRTAPLSSPHDAAIR
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]