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The map label for this gene is mocR [H]

Identifier: 121611627

GI number: 121611627

Start: 5208006

End: 5209484

Strand: Direct

Name: mocR [H]

Synonym: Veis_4721

Alternate gene names: 121611627

Gene position: 5208006-5209484 (Clockwise)

Preceding gene: 121611625

Following gene: 121611629

Centisome position: 93.56

GC content: 63.02

Gene sequence:

>1479_bases
ATGGTCAAACGCTCACGGGGCATGCTGCTACAGTCCATCGCCCTGGATCGCAACGGCGCGCAGTCTCTGTCCACCCAGAT
CTACCGGCAGTTCAAGGAATTGATGCTGGATGGCGCCATCTCGGCGGGCGACCGCCTGCCATCGACGCGCACGATGGCAA
GCGAGTTGGGCGTGGCGCGCGCCACCATCGTCGAAACCTTCGAGCGGCTGGTGGCAGAGGGTTTGCTGGAGTCGCGGGTC
GGTGCCGGCACCCACGTCAGCCAGGCCCTGCATGCGCGTGTGGCGCCGGTCGATGCGCCCCTGGACATCGAATCCATCGC
CAGCGCCAAACTGACGCAGGCCATTGCCATCGCCAAGCATTTCGGCTCGCGCCTGGTGCACAAATACCAACCGTTCACGA
CCGGCACACCCGCCTTCGACGCCTTTCCGATGGCGCAGTGGTTGAGGTTGTCCGGCAAATATTGGCGCAACTCGCGCAGT
CCGCTGTTGAGCTATCCCGACCCGCACGGCGACCTGCACCTGCGCGAAGCCATCGCCACCCATTTGCGCATCAACCGCGG
CATCGCCTGCCATGCCCGGCAGATATTCATCGTCGGCGGCGCCCAATACGCCTTCCAGTTGATCGCAGAAATGCTGATCA
ACGCGGGCGACACCGTGTGGTTCGAAAACCCAGGACACATCGGCGCACGCAACTGCTTCATGCTGGCCGGCGCCAACGTG
CTGGCCGTGCCAGTCGATGAATGCGGCCTGCAAGTCGAGCACGGCCTGCGTCTGGCACCATCGTTCAAACTGGCCTTTGT
CACGCCATCGCACCAGCAGCCCCTGGGCGTCAAAATGAGTCTGGAACGGCGCTTTGCGCTGCTCCAGGCAGCCGAAGCGG
GCGACGCCTGGATTATCGAAGATGACTGGGTGGGCGATTTTTGCGTCACTCCCCTGCCCACACTCAAGGAAATGGACCGC
GGCGGGCGTGTGATTTATGTTGGCAGCTTCAGCAAATCGCTCTTTCCCTCGCTGCGATTAGGCTTCATTCTGGCGCCGCC
GCCACTGGTGCCTCTCTTTTGCACCAGTCTGGAAGCGTTTTCTCCGGGCGTACCAACGCACTTGCAAGCCATCGTCGCCG
AATTCATCAGCGAAGGGCATTTCGCCACCCACATCCGGCGCATGCGCAAACTTTACAAGGAACGCTACGACGCGCTGGTG
CTGGCCTTGAACACCCACCTGTCGCCCTGGCTGAAAGTGGCGCCCACCCAGACCGGCCTGCACACCTGCGCCTACCTGAA
ATGCAGCATCGACCTGGAAGCCCTGTGCGCTGCCGCCGCCAGGAAGGGCGTGACGCTCACCCCGATCAGCCGCTTCAGCA
TTGCGCCGGTCGAGCAGGTAGGCATCGTGATGGGCTTTGCGGCCTACACCCCCCGGCAGATCGAAGAGGCTGTCGTCGTC
ATGCGCGGACTGTTTGAGGCCGCGCCGCGTGTGGATTGA

Upstream 100 bases:

>100_bases
GTGCCGGATTTTCGCGACGATATCGAAGGGGTTATCATTATGCCGGCACGCATTCAAAACGCCTGAATCAAACCCCTTTT
CAAAGCGGCACGCAAAAATA

Downstream 100 bases:

>100_bases
TGCGCGGCGCGGGGCGGCTGGCGCGCGCCGACCTCAGGGAGGCGCTGGATAAATCAGCATCGGTCATTGCGCACTATCTG
GCTGCGAATAAATCAGTGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MVKRSRGMLLQSIALDRNGAQSLSTQIYRQFKELMLDGAISAGDRLPSTRTMASELGVARATIVETFERLVAEGLLESRV
GAGTHVSQALHARVAPVDAPLDIESIASAKLTQAIAIAKHFGSRLVHKYQPFTTGTPAFDAFPMAQWLRLSGKYWRNSRS
PLLSYPDPHGDLHLREAIATHLRINRGIACHARQIFIVGGAQYAFQLIAEMLINAGDTVWFENPGHIGARNCFMLAGANV
LAVPVDECGLQVEHGLRLAPSFKLAFVTPSHQQPLGVKMSLERRFALLQAAEAGDAWIIEDDWVGDFCVTPLPTLKEMDR
GGRVIYVGSFSKSLFPSLRLGFILAPPPLVPLFCTSLEAFSPGVPTHLQAIVAEFISEGHFATHIRRMRKLYKERYDALV
LALNTHLSPWLKVAPTQTGLHTCAYLKCSIDLEALCAAAARKGVTLTPISRFSIAPVEQVGIVMGFAAYTPRQIEEAVVV
MRGLFEAAPRVD

Sequences:

>Translated_492_residues
MVKRSRGMLLQSIALDRNGAQSLSTQIYRQFKELMLDGAISAGDRLPSTRTMASELGVARATIVETFERLVAEGLLESRV
GAGTHVSQALHARVAPVDAPLDIESIASAKLTQAIAIAKHFGSRLVHKYQPFTTGTPAFDAFPMAQWLRLSGKYWRNSRS
PLLSYPDPHGDLHLREAIATHLRINRGIACHARQIFIVGGAQYAFQLIAEMLINAGDTVWFENPGHIGARNCFMLAGANV
LAVPVDECGLQVEHGLRLAPSFKLAFVTPSHQQPLGVKMSLERRFALLQAAEAGDAWIIEDDWVGDFCVTPLPTLKEMDR
GGRVIYVGSFSKSLFPSLRLGFILAPPPLVPLFCTSLEAFSPGVPTHLQAIVAEFISEGHFATHIRRMRKLYKERYDALV
LALNTHLSPWLKVAPTQTGLHTCAYLKCSIDLEALCAAAARKGVTLTPISRFSIAPVEQVGIVMGFAAYTPRQIEEAVVV
MRGLFEAAPRVD
>Mature_492_residues
MVKRSRGMLLQSIALDRNGAQSLSTQIYRQFKELMLDGAISAGDRLPSTRTMASELGVARATIVETFERLVAEGLLESRV
GAGTHVSQALHARVAPVDAPLDIESIASAKLTQAIAIAKHFGSRLVHKYQPFTTGTPAFDAFPMAQWLRLSGKYWRNSRS
PLLSYPDPHGDLHLREAIATHLRINRGIACHARQIFIVGGAQYAFQLIAEMLINAGDTVWFENPGHIGARNCFMLAGANV
LAVPVDECGLQVEHGLRLAPSFKLAFVTPSHQQPLGVKMSLERRFALLQAAEAGDAWIIEDDWVGDFCVTPLPTLKEMDR
GGRVIYVGSFSKSLFPSLRLGFILAPPPLVPLFCTSLEAFSPGVPTHLQAIVAEFISEGHFATHIRRMRKLYKERYDALV
LALNTHLSPWLKVAPTQTGLHTCAYLKCSIDLEALCAAAARKGVTLTPISRFSIAPVEQVGIVMGFAAYTPRQIEEAVVV
MRGLFEAAPRVD

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=313, Percent_Identity=25.5591054313099, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI33469970, Length=313, Percent_Identity=25.5591054313099, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790797, Length=373, Percent_Identity=29.4906166219839, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787710, Length=445, Percent_Identity=25.6179775280899, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53867; Mature: 53867

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRSRGMLLQSIALDRNGAQSLSTQIYRQFKELMLDGAISAGDRLPSTRTMASELGVAR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ATIVETFERLVAEGLLESRVGAGTHVSQALHARVAPVDAPLDIESIASAKLTQAIAIAKH
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FGSRLVHKYQPFTTGTPAFDAFPMAQWLRLSGKYWRNSRSPLLSYPDPHGDLHLREAIAT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHH
HLRINRGIACHARQIFIVGGAQYAFQLIAEMLINAGDTVWFENPGHIGARNCFMLAGANV
HHHHCCCEEEECEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCE
LAVPVDECGLQVEHGLRLAPSFKLAFVTPSHQQPLGVKMSLERRFALLQAAEAGDAWIIE
EEEEHHHHCCCHHCCCEECCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEE
DDWVGDFCVTPLPTLKEMDRGGRVIYVGSFSKSLFPSLRLGFILAPPPLVPLFCTSLEAF
CCCCCCCCCCCCCCHHHHCCCCCEEEEECCCHHHCCHHHCCEEECCCCHHHHHHHHHHHC
SPGVPTHLQAIVAEFISEGHFATHIRRMRKLYKERYDALVLALNTHLSPWLKVAPTQTGL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCCCC
HTCAYLKCSIDLEALCAAAARKGVTLTPISRFSIAPVEQVGIVMGFAAYTPRQIEEAVVV
CEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
MRGLFEAAPRVD
HHHHHHHCCCCC
>Mature Secondary Structure
MVKRSRGMLLQSIALDRNGAQSLSTQIYRQFKELMLDGAISAGDRLPSTRTMASELGVAR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ATIVETFERLVAEGLLESRVGAGTHVSQALHARVAPVDAPLDIESIASAKLTQAIAIAKH
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FGSRLVHKYQPFTTGTPAFDAFPMAQWLRLSGKYWRNSRSPLLSYPDPHGDLHLREAIAT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHH
HLRINRGIACHARQIFIVGGAQYAFQLIAEMLINAGDTVWFENPGHIGARNCFMLAGANV
HHHHCCCEEEECEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCE
LAVPVDECGLQVEHGLRLAPSFKLAFVTPSHQQPLGVKMSLERRFALLQAAEAGDAWIIE
EEEEHHHHCCCHHCCCEECCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEE
DDWVGDFCVTPLPTLKEMDRGGRVIYVGSFSKSLFPSLRLGFILAPPPLVPLFCTSLEAF
CCCCCCCCCCCCCCHHHHCCCCCEEEEECCCHHHCCHHHCCEEECCCCHHHHHHHHHHHC
SPGVPTHLQAIVAEFISEGHFATHIRRMRKLYKERYDALVLALNTHLSPWLKVAPTQTGL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCCCC
HTCAYLKCSIDLEALCAAAARKGVTLTPISRFSIAPVEQVGIVMGFAAYTPRQIEEAVVV
CEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
MRGLFEAAPRVD
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]