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The map label for this gene is gsiC [H]

Identifier: 121611501

GI number: 121611501

Start: 5086627

End: 5087547

Strand: Direct

Name: gsiC [H]

Synonym: Veis_4592

Alternate gene names: 121611501

Gene position: 5086627-5087547 (Clockwise)

Preceding gene: 121611500

Following gene: 121611502

Centisome position: 91.38

GC content: 64.17

Gene sequence:

>921_bases
ATGCTGAATTACTTTCTCAAACGCCTGCTGGGCCTGATCCCGACACTGCTCATCGTGGCCGTGCTGGTGTTCCTGTTCGT
CCACATGCTCCCCGGCGACCCGGCGCGCCTTGCCGCCGGCCAGGGCGCCGACGAGCAGACCGTGGCCATGGTGCGCGCGG
AGCTCGGGCTGGACAAGCCGCTGCTGCAGCAGTTCGTGGGCTTCTTCAGCCACATGCTGCAAGGCGACTTCGGCACCTCG
ATCCGCACGCGGCGGCCGGTGTCGACGGAGATCGGCGAGCGTTTCTTTCCGACGGTGATGCTGACCATCACCAGCATGGT
GTGGGCGGTGATCTTCGGCATGGGCATCGGCATCATCTCGGCCGTGTACCGCAACCAATGGCCCGACCGCATCGGCATGA
CGCTGGCGGTGTCGGGCATCTCCTTTCCTGCATTTGCATTGGGCATGCTGCTGATGCAGATCTTCTCGGTGCAACTCGGC
TGGCTGCCCACGGTGGGCGCCGCGACCTGGAAGCACTACATCCTGCCCTCGATCACGCTGGGCGCGGCCGTAGCGGCCGT
GATGGCCCGCTTCACGCGCGCCTCGTTCGTCGAAGTGATCCAGGAAGATTTCGTGCGCACCGCGCGCGCCAAGGGTGTGC
GCGAATCCAGCGTGGTGTTCAAGCACACGCTGCGCAATGCGCTGATACCGGTGGTCACGATGATGGGCCTGCAGTTCGGC
TTTCTGCTGGGCGGCTCGATCCTCGTGGAGGCGGTGTTCAACTGGCCCGGCCTGGGCCGCCTGCTGGTCGATGCCGTGCA
GATGCGTGACTACCCGGTGATCCAGACGCTGGTGCTGCTGTTCTCGCTCGAATTCATCCTGATCAACCTCGTGGTCGATG
TGCTGTACGGCCTCATCAACCCGACCATCCGCTACAAGTGA

Upstream 100 bases:

>100_bases
CGATTGCCGTGTCGAACTGATCGCCGGTTCCTCGTTTTCTGATGGATTGTCCGGCCGGCGGCGGCACTGTGCCACCGCCC
GCACGCGACATCTGCACCCC

Downstream 100 bases:

>100_bases
GCACGCAGCCATGACGCAAGATTCCGGCGTGCCTGCCGAATCCATCGTTCCTCTTTCTCCTGTCGCCGTGGGGCAAACCG
CGGGCAAGGTCCGCACGCCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLNYFLKRLLGLIPTLLIVAVLVFLFVHMLPGDPARLAAGQGADEQTVAMVRAELGLDKPLLQQFVGFFSHMLQGDFGTS
IRTRRPVSTEIGERFFPTVMLTITSMVWAVIFGMGIGIISAVYRNQWPDRIGMTLAVSGISFPAFALGMLLMQIFSVQLG
WLPTVGAATWKHYILPSITLGAAVAAVMARFTRASFVEVIQEDFVRTARAKGVRESSVVFKHTLRNALIPVVTMMGLQFG
FLLGGSILVEAVFNWPGLGRLLVDAVQMRDYPVIQTLVLLFSLEFILINLVVDVLYGLINPTIRYK

Sequences:

>Translated_306_residues
MLNYFLKRLLGLIPTLLIVAVLVFLFVHMLPGDPARLAAGQGADEQTVAMVRAELGLDKPLLQQFVGFFSHMLQGDFGTS
IRTRRPVSTEIGERFFPTVMLTITSMVWAVIFGMGIGIISAVYRNQWPDRIGMTLAVSGISFPAFALGMLLMQIFSVQLG
WLPTVGAATWKHYILPSITLGAAVAAVMARFTRASFVEVIQEDFVRTARAKGVRESSVVFKHTLRNALIPVVTMMGLQFG
FLLGGSILVEAVFNWPGLGRLLVDAVQMRDYPVIQTLVLLFSLEFILINLVVDVLYGLINPTIRYK
>Mature_306_residues
MLNYFLKRLLGLIPTLLIVAVLVFLFVHMLPGDPARLAAGQGADEQTVAMVRAELGLDKPLLQQFVGFFSHMLQGDFGTS
IRTRRPVSTEIGERFFPTVMLTITSMVWAVIFGMGIGIISAVYRNQWPDRIGMTLAVSGISFPAFALGMLLMQIFSVQLG
WLPTVGAATWKHYILPSITLGAAVAAVMARFTRASFVEVIQEDFVRTARAKGVRESSVVFKHTLRNALIPVVTMMGLQFG
FLLGGSILVEAVFNWPGLGRLLVDAVQMRDYPVIQTLVLLFSLEFILINLVVDVLYGLINPTIRYK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=76.797385620915, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=42.8994082840237, Blast_Score=263, Evalue=9e-72,
Organism=Escherichia coli, GI1789888, Length=308, Percent_Identity=37.6623376623377, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=35.0649350649351, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=38.8379204892966, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=31.4079422382672, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788504, Length=360, Percent_Identity=26.3888888888889, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33824; Mature: 33824

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA