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The map label for this gene is dksA [H]

Identifier: 121611466

GI number: 121611466

Start: 5044492

End: 5045265

Strand: Direct

Name: dksA [H]

Synonym: Veis_4557

Alternate gene names: 121611466

Gene position: 5044492-5045265 (Clockwise)

Preceding gene: 121611465

Following gene: 121611467

Centisome position: 90.62

GC content: 63.95

Gene sequence:

>774_bases
GTGAAAGCCGATACCAGCCCATCCAAAGGGGCCGCCAAGGCAAGCCCTGCGGCGGCGAAAAGCGCCCCGGCGGCTCCCCA
AGCCGCTGCGAAGACCCCGGCCAAGGCGGCTGCAACGACACCCAAGGCCAGCGCGGCGGCCCCGGCGGTGCTGCAAGCCG
GTTCGCAGGTACCCGTGCGCACGACTCGGCCTTCCGCACGACTGGCCCAATTGACCGTACCATCGATGGCGCAGACAGTG
GCCTCGACTGCTGCCAAAGCCAGCTACCGTCACTCCATGCCCACCACCGCGCAAGCACAGCCCACTTACATGGCGATCAA
AAAAGACCCCAAGCTGGCGCACCACTGGAAAACCAAGTCTGCCCAAGAGTTGACCGACGCCGAAGTCATGGCCATGCCCG
ACAGCGAGTACATGAACGACAAGCAGATGGCGTTTTTCCGCATCAAGCTCACGCAGCTCAAGCAGGACATCCACAACAGC
GCCGGCGAAACCACCGAGCACCTGCGCGAAGACACCGTGGTCGTGCCCGACCCGGCCGACCGGGCCACGATAGAAGAAGA
GCATGCGCTGGAGTTGCGCACCCGCGACCGGGAACGCAAACTGCTCAAGAAGATCGAGCAGTCGATCGCCCGCATCGACG
CCGGAAACTACGGCTACTGCGACGAAACCGGCGAACCCATTGGTGTGGCCCGCCTGATCGCGCGCCCCACGGCCACGCTG
TCACTGGAAGCACAACAACGCCGCGAGCTCAAGCAAAAGATGTTTGGCGACTGA

Upstream 100 bases:

>100_bases
GACCTTCTGCCCTTGGCTGCACCACAGCCAAGGGGTTGTCCGCCCGCCCTTGGCTGTACCACAGTCGAGGGATTGCCCGT
ATTGCCAGGAGACCAGCCAA

Downstream 100 bases:

>100_bases
ATCTGACCCAGACCAGATGAACACAGGTTCCGAACCATGAGCAAGGAAGAATCCGCTCCTGCCGGCGGACTGCTATCGAA
GGTGGTGCGGTTCGTGCGCC

Product: TraR/DksA family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKADTSPSKGAAKASPAAAKSAPAAPQAAAKTPAKAAATTPKASAAAPAVLQAGSQVPVRTTRPSARLAQLTVPSMAQTV
ASTAAKASYRHSMPTTAQAQPTYMAIKKDPKLAHHWKTKSAQELTDAEVMAMPDSEYMNDKQMAFFRIKLTQLKQDIHNS
AGETTEHLREDTVVVPDPADRATIEEEHALELRTRDRERKLLKKIEQSIARIDAGNYGYCDETGEPIGVARLIARPTATL
SLEAQQRRELKQKMFGD

Sequences:

>Translated_257_residues
MKADTSPSKGAAKASPAAAKSAPAAPQAAAKTPAKAAATTPKASAAAPAVLQAGSQVPVRTTRPSARLAQLTVPSMAQTV
ASTAAKASYRHSMPTTAQAQPTYMAIKKDPKLAHHWKTKSAQELTDAEVMAMPDSEYMNDKQMAFFRIKLTQLKQDIHNS
AGETTEHLREDTVVVPDPADRATIEEEHALELRTRDRERKLLKKIEQSIARIDAGNYGYCDETGEPIGVARLIARPTATL
SLEAQQRRELKQKMFGD
>Mature_257_residues
MKADTSPSKGAAKASPAAAKSAPAAPQAAAKTPAKAAATTPKASAAAPAVLQAGSQVPVRTTRPSARLAQLTVPSMAQTV
ASTAAKASYRHSMPTTAQAQPTYMAIKKDPKLAHHWKTKSAQELTDAEVMAMPDSEYMNDKQMAFFRIKLTQLKQDIHNS
AGETTEHLREDTVVVPDPADRATIEEEHALELRTRDRERKLLKKIEQSIARIDAGNYGYCDETGEPIGVARLIARPTATL
SLEAQQRRELKQKMFGD

Specific function: Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed. [C]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=121, Percent_Identity=42.9752066115703, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 27741; Mature: 27741

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADTSPSKGAAKASPAAAKSAPAAPQAAAKTPAKAAATTPKASAAAPAVLQAGSQVPVR
CCCCCCCCCCCCCCCCCHHCCCCCCCHHHHCCCCHHHCCCCCCHHCCHHHHHCCCCCCCE
TTRPSARLAQLTVPSMAQTVASTAAKASYRHSMPTTAQAQPTYMAIKKDPKLAHHWKTKS
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHCCCC
AQELTDAEVMAMPDSEYMNDKQMAFFRIKLTQLKQDIHNSAGETTEHLREDTVVVPDPAD
HHHHCCCCEEECCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCEECCCCCC
RATIEEEHALELRTRDRERKLLKKIEQSIARIDAGNYGYCDETGEPIGVARLIARPTATL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEE
SLEAQQRRELKQKMFGD
EECHHHHHHHHHHHCCC
>Mature Secondary Structure
MKADTSPSKGAAKASPAAAKSAPAAPQAAAKTPAKAAATTPKASAAAPAVLQAGSQVPVR
CCCCCCCCCCCCCCCCCHHCCCCCCCHHHHCCCCHHHCCCCCCHHCCHHHHHCCCCCCCE
TTRPSARLAQLTVPSMAQTVASTAAKASYRHSMPTTAQAQPTYMAIKKDPKLAHHWKTKS
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHCCCC
AQELTDAEVMAMPDSEYMNDKQMAFFRIKLTQLKQDIHNSAGETTEHLREDTVVVPDPAD
HHHHCCCCEEECCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCEECCCCCC
RATIEEEHALELRTRDRERKLLKKIEQSIARIDAGNYGYCDETGEPIGVARLIARPTATL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEE
SLEAQQRRELKQKMFGD
EECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555902 [H]