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The map label for this gene is yjiA [H]

Identifier: 121611465

GI number: 121611465

Start: 5043106

End: 5044176

Strand: Direct

Name: yjiA [H]

Synonym: Veis_4556

Alternate gene names: 121611465

Gene position: 5043106-5044176 (Clockwise)

Preceding gene: 121611464

Following gene: 121611466

Centisome position: 90.59

GC content: 63.03

Gene sequence:

>1071_bases
ATGTCCCTGATCCCCGTCACCATCCTTACCGGCTTTCTTGGCTCCGGCAAAACGACCTTGCTCAAGCGCCTGCTGAGCGA
AGCCCATGGCCAGAAGATCGCCGTGATCGAGAACGAATTCGGCGCCGAAAACATCGACACCGACATCCTCGTGACCGAGT
CCAAAGAGCAGATCGTGCAGATGAACAATGGCTGCATCTGCTGCACCATCCGCGAAGACCTGCGCGCAACGCTGCAACTG
CTGGCCAGCAAAAAGCGCCAGGGCCTGCTGGACTTCGAGCGCATCGTGATCGAGACCACCGGCCTGGCGGACCCCGGCCC
GGTGGCGCAGACCTTCTTCATGGATGACGAGGTCGCCCAGAGTTGCCTGATCGACGCCATCATCACGCTGGTGGACGCCA
AGCATGCCACCGGGCAACTGAACGACCGCCAGGAGGCCAGGCGCCAAGTGGGCTTTGCCGACCAGATCTTCCTGTCCAAG
ACCGATCTCGTGAGCGCCGAGGAAACCCGGGCGCTGATTCAGCGCCTGAAACACATGAACCCGCGCGCGCCGATACAGGC
CGTGCACTTTGGCGCCGTGCCGATCGGGCAGGTGCTCGATCTGCGGGGCTTCAACCTGCATGCCAAGCTCGACATCGATC
CGGACTTCCTGAGCGAACAAGACGCGCACGGGCATGGGCACGAGCATGAGCATGAGCACCACGAGCACGCGCATGGCGCG
CATTGCGACCACCCCTCGCACCAGCATGGCGGCCCGGGCCACCATCACCACGATGACGATGTCAAGAGCTTCGTCTTCCG
CTCGGAGCGCCCGTTCGATCCCGCCCGGCTGGAGGACTTCCTGGGCGCAATGGTCAACGTTTATGGCCCGCGCATGCTGC
GCTACAAGGGCGTGCTGCAGATGAAGGGCACGGACCGCAAGGTGATCTTCCAGGGCGTGCACCAACTCATGGGCAGCGAT
CTGGGCCCGCAATGGGCCGACGGCGAGGCCCGCACCAGCAAGATGGTCTTCATTGGCATCGACCTGCCCCGGGACATCTT
CTTGCAGGGGCTGGAACAAAGCCTTGTCTGA

Upstream 100 bases:

>100_bases
CGCATGCCGCCGAAAAGCGCCCCAGCCCGTCCGGGCCAGGATCACGCAGCACCGGCCCCGCTAAACTCCCCGACGCCGTT
GGCAAACCATGAGGCCTCCC

Downstream 100 bases:

>100_bases
AGGGGCCGGCGCTGCGGCAGTCCCGGCGCGACCCGGGGCCTGTGTCGTATGCGCAACGGTTTTGTGGGTATCAGTACAGA
TCGATACAATCGCGGCCCGG

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSLIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGAENIDTDILVTESKEQIVQMNNGCICCTIREDLRATLQL
LASKKRQGLLDFERIVIETTGLADPGPVAQTFFMDDEVAQSCLIDAIITLVDAKHATGQLNDRQEARRQVGFADQIFLSK
TDLVSAEETRALIQRLKHMNPRAPIQAVHFGAVPIGQVLDLRGFNLHAKLDIDPDFLSEQDAHGHGHEHEHEHHEHAHGA
HCDHPSHQHGGPGHHHHDDDVKSFVFRSERPFDPARLEDFLGAMVNVYGPRMLRYKGVLQMKGTDRKVIFQGVHQLMGSD
LGPQWADGEARTSKMVFIGIDLPRDIFLQGLEQSLV

Sequences:

>Translated_356_residues
MSLIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGAENIDTDILVTESKEQIVQMNNGCICCTIREDLRATLQL
LASKKRQGLLDFERIVIETTGLADPGPVAQTFFMDDEVAQSCLIDAIITLVDAKHATGQLNDRQEARRQVGFADQIFLSK
TDLVSAEETRALIQRLKHMNPRAPIQAVHFGAVPIGQVLDLRGFNLHAKLDIDPDFLSEQDAHGHGHEHEHEHHEHAHGA
HCDHPSHQHGGPGHHHHDDDVKSFVFRSERPFDPARLEDFLGAMVNVYGPRMLRYKGVLQMKGTDRKVIFQGVHQLMGSD
LGPQWADGEARTSKMVFIGIDLPRDIFLQGLEQSLV
>Mature_355_residues
SLIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGAENIDTDILVTESKEQIVQMNNGCICCTIREDLRATLQLL
ASKKRQGLLDFERIVIETTGLADPGPVAQTFFMDDEVAQSCLIDAIITLVDAKHATGQLNDRQEARRQVGFADQIFLSKT
DLVSAEETRALIQRLKHMNPRAPIQAVHFGAVPIGQVLDLRGFNLHAKLDIDPDFLSEQDAHGHGHEHEHEHHEHAHGAH
CDHPSHQHGGPGHHHHDDDVKSFVFRSERPFDPARLEDFLGAMVNVYGPRMLRYKGVLQMKGTDRKVIFQGVHQLMGSDL
GPQWADGEARTSKMVFIGIDLPRDIFLQGLEQSLV

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=366, Percent_Identity=31.4207650273224, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI126722884, Length=366, Percent_Identity=31.6939890710383, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI146231952, Length=366, Percent_Identity=31.9672131147541, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI148727351, Length=366, Percent_Identity=31.4207650273224, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI223941779, Length=366, Percent_Identity=31.4207650273224, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI223941776, Length=356, Percent_Identity=30.0561797752809, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI119120938, Length=165, Percent_Identity=39.3939393939394, Blast_Score=118, Evalue=6e-27,
Organism=Escherichia coli, GI87082430, Length=346, Percent_Identity=38.150289017341, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788499, Length=233, Percent_Identity=33.9055793991416, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=226, Percent_Identity=31.858407079646, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 39640; Mature: 39508

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGAENIDTDILVTESKEQIVQ
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
MNNGCICCTIREDLRATLQLLASKKRQGLLDFERIVIETTGLADPGPVAQTFFMDDEVAQ
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCCHHHEECCHHHHH
SCLIDAIITLVDAKHATGQLNDRQEARRQVGFADQIFLSKTDLVSAEETRALIQRLKHMN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PRAPIQAVHFGAVPIGQVLDLRGFNLHAKLDIDPDFLSEQDAHGHGHEHEHEHHEHAHGA
CCCCEEEEEECCCCHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHCCCC
HCDHPSHQHGGPGHHHHDDDVKSFVFRSERPFDPARLEDFLGAMVNVYGPRMLRYKGVLQ
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCEEE
MKGTDRKVIFQGVHQLMGSDLGPQWADGEARTSKMVFIGIDLPRDIFLQGLEQSLV
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIPVTILTGFLGSGKTTLLKRLLSEAHGQKIAVIENEFGAENIDTDILVTESKEQIVQ
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
MNNGCICCTIREDLRATLQLLASKKRQGLLDFERIVIETTGLADPGPVAQTFFMDDEVAQ
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCCHHHEECCHHHHH
SCLIDAIITLVDAKHATGQLNDRQEARRQVGFADQIFLSKTDLVSAEETRALIQRLKHMN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC
PRAPIQAVHFGAVPIGQVLDLRGFNLHAKLDIDPDFLSEQDAHGHGHEHEHEHHEHAHGA
CCCCEEEEEECCCCHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHCCCC
HCDHPSHQHGGPGHHHHDDDVKSFVFRSERPFDPARLEDFLGAMVNVYGPRMLRYKGVLQ
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCEEE
MKGTDRKVIFQGVHQLMGSDLGPQWADGEARTSKMVFIGIDLPRDIFLQGLEQSLV
ECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]