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The map label for this gene is hipO [H]

Identifier: 121611172

GI number: 121611172

Start: 4695173

End: 4696351

Strand: Direct

Name: hipO [H]

Synonym: Veis_4256

Alternate gene names: 121611172

Gene position: 4695173-4696351 (Clockwise)

Preceding gene: 121611166

Following gene: 121611174

Centisome position: 84.34

GC content: 65.99

Gene sequence:

>1179_bases
ATGAACTCGCAAAACTTCAACGGCCTCGAGGCGTTGACCCGACTCCGCCAGGACATCCATCGCCACCCCGAATTGGCTTT
CGAAGAGCGCCGCACCGCCGGCATCGTGGCCGCCTACCTTCACTCCTTGGGCATCGAAGTGCACACCGAGGTGGGCCGCA
CCGGCGTCGTCGGCGTCATCCCGGGCAAGACCAACCGTAGCCAGCGGTCCATCGGCCTGCGCGCCGACATGGACGCACTG
GCCATGCCGGACCACAAGCCAGTGCCGCACCGCTCCACCTGCGAAGGCGTGATGCACGGATGCGGCCATGATGGCCACAC
CGCCATGCTGCTCGGCGCGGCCGCCGAACTGGCACGCACGCGCGCTTTCGACGGCACGGTGGTGCTGATCTTCCAGCCCG
CAGAAGAAGGCGCCGGCGGCGCCAAGGCGATGCTGGACGATGGACTGCTGGAGCGCTTTCCGGTGGAGTCGTTCTGGGGC
CTGCACAACTGGCCAGGAGTGCCACTTGGCCAGGCAGTCATCCACGCCACGGCCTGCATGGCCGCAGTCGATTACTTCGA
CATCGACGTGCTGGGCAAGGGTTGCCACGGTGGCATGCCGCAGGAAGGCATCGACGCAGTGCTGGCTGCGGCGCACATCG
TGACCGCGCTGCAATCGATTCCCGCGCGCAACGTGCATCCATTGGACTCGGCAGTGGTGGGCGTTGCAAAAATCCACGGT
GGCCAGGCGTATCACGTCGGCCCGGAGGTGGTGACGCTCAGCGGTTCGGTGCGTGCGCACAAGGAATCTGTGCGCGCCCT
GGTCGAGCACCGCCTGCACGAGGTGGCCGAGAACGCGGCGGCGGCCTTGGGGGCAAAGGTTCGCATCCGCTACCAGCGCA
ACTATCCTGCGACGGTGAATGATCCGGCGCTCGCCGACATCGCGTCAGAGGTGGCCGCATCGGTTCTGGGCGCGGAAAAG
GTCGTGCGCGACCGTCTGCCGTCCATGGCCGCCGAAGACTTCTCTTTCTTCTCCCGCGAGCGCCCGGGCTGCTATGTGTG
GATGGGCAATGACGATGCCGACCACATCATGAGCCTGCACCACCCGAAATACGACTTCAACGATCGGCTGATCGGGCATG
GCATGGCGTACTGGACACGGCTCGTCAGCCGCGTCTTGCCGGTCGCGCCGCACCTCTGA

Upstream 100 bases:

>100_bases
TGCAACGCCGCGATGCGCTTCGATGGCCAGCGCAGACCGACAGATGATCGGTGACGCGACACTAGGCCCGACTGCTGCGT
CAACCGGAAAGACCCATGCC

Downstream 100 bases:

>100_bases
AGGCGTCATGTGGTCATGTATTCTCCGGCGAGCAGCGGACTGAAGCGTTGGCCGGCTTTCCGTGCGGTCGCATGTACCGG
CCCACAAAAATGGCGTCGGA

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNSQNFNGLEALTRLRQDIHRHPELAFEERRTAGIVAAYLHSLGIEVHTEVGRTGVVGVIPGKTNRSQRSIGLRADMDAL
AMPDHKPVPHRSTCEGVMHGCGHDGHTAMLLGAAAELARTRAFDGTVVLIFQPAEEGAGGAKAMLDDGLLERFPVESFWG
LHNWPGVPLGQAVIHATACMAAVDYFDIDVLGKGCHGGMPQEGIDAVLAAAHIVTALQSIPARNVHPLDSAVVGVAKIHG
GQAYHVGPEVVTLSGSVRAHKESVRALVEHRLHEVAENAAAALGAKVRIRYQRNYPATVNDPALADIASEVAASVLGAEK
VVRDRLPSMAAEDFSFFSRERPGCYVWMGNDDADHIMSLHHPKYDFNDRLIGHGMAYWTRLVSRVLPVAPHL

Sequences:

>Translated_392_residues
MNSQNFNGLEALTRLRQDIHRHPELAFEERRTAGIVAAYLHSLGIEVHTEVGRTGVVGVIPGKTNRSQRSIGLRADMDAL
AMPDHKPVPHRSTCEGVMHGCGHDGHTAMLLGAAAELARTRAFDGTVVLIFQPAEEGAGGAKAMLDDGLLERFPVESFWG
LHNWPGVPLGQAVIHATACMAAVDYFDIDVLGKGCHGGMPQEGIDAVLAAAHIVTALQSIPARNVHPLDSAVVGVAKIHG
GQAYHVGPEVVTLSGSVRAHKESVRALVEHRLHEVAENAAAALGAKVRIRYQRNYPATVNDPALADIASEVAASVLGAEK
VVRDRLPSMAAEDFSFFSRERPGCYVWMGNDDADHIMSLHHPKYDFNDRLIGHGMAYWTRLVSRVLPVAPHL
>Mature_392_residues
MNSQNFNGLEALTRLRQDIHRHPELAFEERRTAGIVAAYLHSLGIEVHTEVGRTGVVGVIPGKTNRSQRSIGLRADMDAL
AMPDHKPVPHRSTCEGVMHGCGHDGHTAMLLGAAAELARTRAFDGTVVLIFQPAEEGAGGAKAMLDDGLLERFPVESFWG
LHNWPGVPLGQAVIHATACMAAVDYFDIDVLGKGCHGGMPQEGIDAVLAAAHIVTALQSIPARNVHPLDSAVVGVAKIHG
GQAYHVGPEVVTLSGSVRAHKESVRALVEHRLHEVAENAAAALGAKVRIRYQRNYPATVNDPALADIASEVAASVLGAEK
VVRDRLPSMAAEDFSFFSRERPGCYVWMGNDDADHIMSLHHPKYDFNDRLIGHGMAYWTRLVSRVLPVAPHL

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=413, Percent_Identity=29.2978208232446, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42265; Mature: 42265

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQNFNGLEALTRLRQDIHRHPELAFEERRTAGIVAAYLHSLGIEVHTEVGRTGVVGVI
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
PGKTNRSQRSIGLRADMDALAMPDHKPVPHRSTCEGVMHGCGHDGHTAMLLGAAAELART
CCCCCCCHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RAFDGTVVLIFQPAEEGAGGAKAMLDDGLLERFPVESFWGLHNWPGVPLGQAVIHATACM
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHH
AAVDYFDIDVLGKGCHGGMPQEGIDAVLAAAHIVTALQSIPARNVHPLDSAVVGVAKIHG
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GQAYHVGPEVVTLSGSVRAHKESVRALVEHRLHEVAENAAAALGAKVRIRYQRNYPATVN
CEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
DPALADIASEVAASVLGAEKVVRDRLPSMAAEDFSFFSRERPGCYVWMGNDDADHIMSLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHC
HPKYDFNDRLIGHGMAYWTRLVSRVLPVAPHL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNSQNFNGLEALTRLRQDIHRHPELAFEERRTAGIVAAYLHSLGIEVHTEVGRTGVVGVI
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
PGKTNRSQRSIGLRADMDALAMPDHKPVPHRSTCEGVMHGCGHDGHTAMLLGAAAELART
CCCCCCCHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RAFDGTVVLIFQPAEEGAGGAKAMLDDGLLERFPVESFWGLHNWPGVPLGQAVIHATACM
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHH
AAVDYFDIDVLGKGCHGGMPQEGIDAVLAAAHIVTALQSIPARNVHPLDSAVVGVAKIHG
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GQAYHVGPEVVTLSGSVRAHKESVRALVEHRLHEVAENAAAALGAKVRIRYQRNYPATVN
CEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
DPALADIASEVAASVLGAEKVVRDRLPSMAAEDFSFFSRERPGCYVWMGNDDADHIMSLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHC
HPKYDFNDRLIGHGMAYWTRLVSRVLPVAPHL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]