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The map label for this gene is nrdR

Identifier: 121611163

GI number: 121611163

Start: 4685840

End: 4686289

Strand: Direct

Name: nrdR

Synonym: Veis_4247

Alternate gene names: 121611163

Gene position: 4685840-4686289 (Clockwise)

Preceding gene: 121611162

Following gene: 121611165

Centisome position: 84.18

GC content: 62.0

Gene sequence:

>450_bases
ATGAAATGCCCCTTTTGCAGCCACCTCGAAACCCAGGTCATCGAAACCCGGGTCTTCGAGGATGCCGCATCCATCCGCCG
CCGGCGCCAATGCGCCGCCTGCAGCAAGCGCTTTACCACTTACGAGCGCTCGGACGTGAGCTTTCCGGCCGTCGTGAAAA
AAGACGGCCGCCGCGTCGAATACGGGCACGACAAGTTGCTCGCCTCGTTCAAACTGGCGCTGCGCAAGCGCCCGGTCAGC
ACCGGACGGATCGACAGCGCCATCGAGCGCATCGAGGAAAAGCTGCTCAACCTCGGGCTGCGCGAAGTGCCCTCCAGCCG
CATTGGCGAGTTGGTGATGCGCGAGCTCAAGAAGCTCGACAAGGTAGCCTACATCCGCTTTGCCAGCGTGTACCGCAGTT
TCGAGGGCATCGACGACTTTCGCGCCCTGGTCGATGAGGTGCGCAAATGA

Upstream 100 bases:

>100_bases
GCGGTGCGCGCCAAGGTCGACGCGCTGACGGCCCGCTTTCCGGTCTACGGCTGATGGCGCTCTGCGTCCGGCCGCCCGAT
GAAGCCGCCATGAAGCCGCC

Downstream 100 bases:

>100_bases
TGCGGCGGCGGCTTTCAGTGCGGCGCGTCCGGGCCGTCGGCGCCGCCTGAGCCTTTGACGGCGGCGGTGGCGGCGTGCAA
TGCGGCCTTGTCCCCCGCAG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKCPFCSHLETQVIETRVFEDAASIRRRRQCAACSKRFTTYERSDVSFPAVVKKDGRRVEYGHDKLLASFKLALRKRPVS
TGRIDSAIERIEEKLLNLGLREVPSSRIGELVMRELKKLDKVAYIRFASVYRSFEGIDDFRALVDEVRK

Sequences:

>Translated_149_residues
MKCPFCSHLETQVIETRVFEDAASIRRRRQCAACSKRFTTYERSDVSFPAVVKKDGRRVEYGHDKLLASFKLALRKRPVS
TGRIDSAIERIEEKLLNLGLREVPSSRIGELVMRELKKLDKVAYIRFASVYRSFEGIDDFRALVDEVRK
>Mature_149_residues
MKCPFCSHLETQVIETRVFEDAASIRRRRQCAACSKRFTTYERSDVSFPAVVKKDGRRVEYGHDKLLASFKLALRKRPVS
TGRIDSAIERIEEKLLNLGLREVPSSRIGELVMRELKKLDKVAYIRFASVYRSFEGIDDFRALVDEVRK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=52.1428571428571, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_VEREI (A1WQP5)

Other databases:

- EMBL:   CP000542
- RefSeq:   YP_998970.1
- STRING:   A1WQP5
- GeneID:   4694389
- GenomeReviews:   CP000542_GR
- KEGG:   vei:Veis_4247
- NMPDR:   fig|391735.5.peg.3892
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1WQP5
- ProtClustDB:   PRK00464
- BioCyc:   VEIS391735:VEIS_4247-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17272; Mature: 17272

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCSHLETQVIETRVFEDAASIRRRRQCAACSKRFTTYERSDVSFPAVVKKDGRRVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
YGHDKLLASFKLALRKRPVSTGRIDSAIERIEEKLLNLGLREVPSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEGIDDFRALVDEVRK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCSHLETQVIETRVFEDAASIRRRRQCAACSKRFTTYERSDVSFPAVVKKDGRRVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
YGHDKLLASFKLALRKRPVSTGRIDSAIERIEEKLLNLGLREVPSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEGIDDFRALVDEVRK
HHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA